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Xuming Deng

Xuming Deng

D-Index & Metrics

Microbiology

D-Index
59
Citations
11655
World Ranking
3290
National Ranking
78

Overview

Xuming Deng is affiliated with Jilin University in China and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research focuses on molecular biology, food science, molecular medicine, epidemiology, and pharmacology, with a significant emphasis on topics including antibiotic resistance in bacteria, Salmonella and Campylobacter epidemiology, and Vibrio bacteria research studies.

The scientist's recent publications reflect a wide range of experimental and applied research in molecular and cellular biology. Notable recent papers include:

  • "Enhanced Keap1-Nrf2/Trx-1 axis by daphnetin protects against oxidative stress-driven hepatotoxicity via inhibiting ASK1/JNK and Txnip/NLRP3 inflammasome activation" (2020, Phytomedicine)
  • "Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2" (2022, Phytomedicine)
  • "A novel inhibitor of monooxygenase reversed the activity of tetracyclines against tet(X3)/tet(X4)-positive bacteria" (2022, EBioMedicine)
  • "A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection" (2020, Frontiers in Cellular and Infection Microbiology)
  • "Sodium sulfite triggered hepatic apoptosis, necroptosis, and pyroptosis by inducing mitochondrial damage in mice and AML-12 cells" (2024, Journal of Hazardous Materials)

Deng has collaborated frequently with a group of coauthors, including Jianfeng Wang, Jiazhang Qiu, Yonglin Zhou, Qianghua Lv, and Tianqi Fang. Their collaborative work has contributed to the scientist's extensive publication record, which includes a substantial number of papers in key journals such as Phytomedicine, Molecules, Microbiology Spectrum, Journal of Dairy Science, and Journal of Agricultural and Food Chemistry.

Their work often addresses the mechanisms underlying bacterial resistance to antibiotics, the pharmacokinetics and efficacy of antibiotics, as well as the interaction between gut microbiota and human health. Other areas of interest include essential oils and their antimicrobial activity, and research on Clostridium difficile and Clostridium perfringens.

This scientist's contributions encompass epidemiological research as well as molecular and cellular studies, providing insights relevant to infectious disease control and the development of novel therapeutic approaches. Their interdisciplinary approach spans biochemistry and molecular biology to applied topics in food science and medicine.

Best Publications

  • A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin

    Yang Wang;Yuan Lv;Jiachang Cai;Stefan Schwarz

  • Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis.

    Hongming Lv;Qinmei Liu;Zhongmei Wen;Haihua Feng

  • Anti-inflammatory effects of linalool in RAW 264.7 macrophages and lipopolysaccharide-induced lung injury model

    Meixia Huo;Xiurui Cui;Jiangdong Xue;Gefu Chi

  • Kaempferol regulates MAPKs and NF-κB signaling pathways to attenuate LPS-induced acute lung injury in mice.

    Xiaojun Chen;Xiaofeng Yang;Tianjiao Liu;Mingfeng Guan

  • Ivermectin inhibits LPS-induced production of inflammatory cytokines and improves LPS-induced survival in mice.

    X. Zhang;Y. Song;X. Ci;N. An

  • Subinhibitory Concentrations of Thymol Reduce Enterotoxins A and B and α-Hemolysin Production in Staphylococcus aureus Isolates

    Jiazhang Qiu;Dacheng Wang;Hua Xiang;Haihua Feng

  • Baicalin Protects Mice From Staphylococcus aureus Pneumonia Via Inhibition of the Cytolytic Activity of α-Hemolysin

    Jiazhang Qiu;Xiaodi Niu;Jing Dong;Dacheng Wang

  • Eugenol reduces the expression of virulence-related exoproteins in Staphylococcus aureus.

    Jiazhang Qiu;Haihua Feng;Jing Lu;Hua Xiang

  • Schisantherin A Exhibits Anti-inflammatory Properties by Down-Regulating NF-κB and MAPK Signaling Pathways in Lipopolysaccharide-Treated RAW 264.7 Cells

    Xinxin Ci;Rong Ren;Kan Xu;Hongyu Li

  • Licochalcone A Inhibits Lipopolysaccharide-Induced Inflammatory Response in Vitro and in Vivo

    Xiao Chu;Xinxin Ci;Miaomiao Wei;Xiaofeng Yang

  • Anti-inflammatory effects of ivermectin in mouse model of allergic asthma

    Shuhan Yan;Xinxin Ci;Na Chen;Chi Chen

  • Effects of a Natural Prolyl Oligopeptidase Inhibitor, Rosmarinic Acid, on Lipopolysaccharide-Induced Acute Lung Injury in Mice

    Xiao Chu;Xinxin Ci;Jiakang He;Lanxiang Jiang

  • Daphnetin-mediated Nrf2 antioxidant signaling pathways ameliorate tert-butyl hydroperoxide (t-BHP)-induced mitochondrial dysfunction and cell death.

    Hongming Lv;Qinmei Liu;Junfeng Zhou;Guangyun Tan

  • Subinhibitory concentrations of perilla oil affect the expression of secreted virulence factor genes in Staphylococcus aureus.

    Jiazhang Qiu;Xiaoran Zhang;Mingjing Luo;Hongen Li

  • Protective effect of florfenicol on acute lung injury induced by lipopolysaccharide in mice.

    Xuemei Zhang;Keji Song;Huanzhang Xiong;Hongyu Li

  • Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-κB signaling pathway.

    Lanan Wassy Soromou;Na Chen;Lanxiang Jiang;Meixia Huo

  • In vitro and in vivo protection provided by pinocembrin against lipopolysaccharide-induced inflammatory responses.

    Lanan Wassy Soromou;Xiao Chu;Lanxiang Jiang;Miaomiao Wei

  • Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A.

    Hongming Lv;Huahong Yang;Zhongfeng Wang;Haihua Feng

  • Regulation of inflammatory cytokines in lipopolysaccharide-stimulated RAW 264.7 murine macrophage by 7-O-methyl-naringenin.

    Lanan Wassy Soromou;Zhichao Zhang;Rongtao Li;Na Chen

  • Spontaneous Atherosclerosis in Aged Lipoprotein Lipase–Deficient Mice With Severe Hypertriglyceridemia on a Normal Chow Diet

    Xiaohong Zhang;Rong Qi;Xunde Xian;Fei Yang

  • Antifungal activity of thymol against clinical isolates of fluconazole-sensitive and -resistant Candida albicans.

    Na Guo;Jingbo Liu;Xiuping Wu;Xingming Bi

Frequent Co-Authors

Qi Jin
Qi Jin Peking Union Medical College Hospital
Yang Wang
Yang Wang China Agricultural University
Zhao-Qing Luo
Zhao-Qing Luo Purdue University West Lafayette
Genhong Cheng
Genhong Cheng University of California, Los Angeles
Jian Yang
Jian Yang University of Birmingham
Michael R. Hayden
Michael R. Hayden University of British Columbia
Xuegong Zhang
Xuegong Zhang Tsinghua University
Jianglin Fan
Jianglin Fan University of Yamanashi
Boon Chin Heng
Boon Chin Heng Peking University
Guanghua Li
Guanghua Li Jilin University

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