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Molecular Biology

D-Index
56
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26350
World Ranking
2175
National Ranking
51

Overview

Marco Demaria is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily addresses topics within medicine, biochemistry, genetics, and molecular biology, with a specific focus on physiology, molecular biology, immunology, pulmonary and respiratory medicine, and oncology.

The scientist's work centers on several main topics: telomeres, telomerase, and senescence; neutrophil, myeloperoxidase, and oxidative mechanisms; immune cells in cancer; genetics, aging, and longevity in model organisms; single-cell and spatial transcriptomics; advanced biosensing and bioanalysis techniques; and epigenetics and DNA methylation.

Marco Demaria's recent published papers include:

  • "Senescence and cancer - role and therapeutic opportunities," 2022, Nature Reviews Clinical Oncology
  • "Senescent Cells in Cancer Therapy: Friends or Foes?", 2020, Trends in Cancer
  • "The senescence-associated secretory phenotype and its physiological and pathological implications," 2024, Nature Reviews Molecular Cell Biology
  • "A Senescence-Centric View of Aging: Implications for Longevity and Disease," 2020, Trends in Cell Biology
  • "Cellular Senescence and the Senescence-Associated Secretory Phenotype as Drivers of Skin Photoaging," 2020, Journal of Investigative Dermatology

Frequent co-authors collaborating with Marco Demaria include Boshi Wang, Marta Varela-Eirín, Judith Campisi, Vassilis G. Gorgoulis, and Jamil Nehme.

The scientist has published extensively in several scientific venues, notably:

  • Aging Cell
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Aging

Additionally, Marco Demaria has contributed to book publications. One known book is Senolytics in Disease, Ageing and Longevity, published in 2020 by Springer International Publishing.

Best Publications

  • Cellular Senescence: Defining a Path Forward

    Vassilis Gorgoulis;Peter D. Adams;Andrea Alimonti;Dorothy C. Bennett

  • Hallmarks of Cellular Senescence.

    Alejandra Hernandez-Segura;Jamil Nehme;Marco Demaria

  • An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

    Marco Demaria;Naoko Ohtani;Sameh A Youssef;Francis Rodier

  • Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.

    Jianhui Chang;Yingying Wang;Yingying Wang;Lijian Shao;Remi Martin Laberge

  • Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment.

    Ok Hee Jeon;Chaekyu Kim;Chaekyu Kim;Remi Martin Laberge;Marco Demaria;Marco Demaria

  • Cellular senescence promotes adverse effects of chemotherapy and cancer relapse

    Marco Demaria;Marco Demaria;Monique N. O'Leary;Jianhui Chang;Lijian Shao

  • MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

    Remi Martin Laberge;Yu Sun;Arturo V. Orjalo;Christopher K. Patil

  • Cellular Senescence: Aging, Cancer, and Injury

    Arianna Calcinotto;Jaskaren Kohli;Elena Zagato;Laura Pellegrini

  • Lamin B1 loss is a senescence-associated biomarker

    Adam Freund;Adam Freund;Adam Freund;Remi-Martin Laberge;Marco Demaria;Judith Campisi;Judith Campisi

  • The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

    Chanhee Kang;Qikai Xu;Timothy D Martin;Mamie Z Li

  • Unmasking Transcriptional Heterogeneity in Senescent Cells

    Alejandra Hernandez-Segura;Tristan V. de Jong;Simon Melov;Victor Guryev

  • Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

    Allyson K. Palmer;Ming Xu;Ming Xu;Yi Zhu;Tamar Pirtskhalava

  • Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson's Disease

    Shankar J. Chinta;Georgia Woods;Marco Demaria;Anand Rane

  • Senescent Cells in Cancer Therapy: Friends or Foes?

    Boshi Wang;Jaskaren Kohli;Marco Demaria

  • A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction

    Marco Demaria;Marco Demaria;Carlotta Giorgi;Magdalena Lebiedzinska;Giovanna Esposito

  • Cellular senescence and the aging brain.

    Shankar J Chinta;Georgia Woods;Anand Rane;Marco Demaria

  • Glucocorticoids Suppress Selected Components of the Senescence-Associated Secretory Phenotype

    Remi-Martin Laberge;Lili Zhou;Lili Zhou;Melissa R Sarantos;Francis Rodier

  • Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease?

    Shankar J Chinta;Christopher A Lieu;Marco DeMaria;Remi-Martin Laberge

  • Therapeutic interventions for aging: the case of cellular senescence.

    Abel Soto-Gamez;Marco Demaria

  • A Senescence-Centric View of Aging: Implications for Longevity and Disease

    M Borghesan;W M H Hoogaars;M Varela-Eirin;N Talma

Frequent Co-Authors

Judith Campisi
Judith Campisi Buck Institute for Research on Aging
Tamar Tchkonia
Tamar Tchkonia Cedars-Sinai Medical Center
Jennifer H. Elisseeff
Jennifer H. Elisseeff Johns Hopkins University
Valeria Poli
Valeria Poli University of Turin
Pankaj Kapahi
Pankaj Kapahi Buck Institute for Research on Aging
Vassilis G. Gorgoulis
Vassilis G. Gorgoulis National and Kapodistrian University of Athens
Julie K. Andersen
Julie K. Andersen Buck Institute for Research on Aging
Paolo Pinton
Paolo Pinton University of Ferrara

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