World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
98
Citations
51139
World Ranking
8761
National Ranking
4518

Overview

Tamar Tchkonia is affiliated with Cedars-Sinai Medical Center in the United States. Their research primarily focuses on fields related to Medicine and Biochemistry, Genetics, and Molecular Biology, with significant contributions in subfields such as Physiology, Molecular Biology, Immunology, Aging, and Epidemiology.

The scientist's work extensively covers topics including Telomeres, Telomerase, and Senescence; Genetics, Aging, and Longevity in Model Organisms; Neutrophil, Myeloperoxidase and Oxidative Mechanisms; Single-cell and Spatial Transcriptomics; Circadian Rhythm and Melatonin; Adipokines, Inflammation, and Metabolic Diseases; and Skin Protection and Aging.

Recent notable papers co-authored by Tamar Tchkonia include:

  • Senolytic drugs: from discovery to translation (2020), published in Journal of Internal Medicine
  • Cellular senescence and senolytics: the path to the clinic (2022), published in Nature Medicine
  • A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues (2022), published in Nature Communications
  • The role of cellular senescence in ageing and endocrine disease (2020), published in Nature Reviews Endocrinology
  • Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice (2021), published in Aging Cell

Frequent co-authors working with Tamar Tchkonia are:

  • James L. Kirkland
  • Sundeep Khosla
  • Paul D. Robbins
  • Tamar Pirtskhalava
  • Yi Zhu

The scientist has published numerous articles in prominent venues, with frequent publications in:

  • Aging Cell
  • bioRxiv (Cold Spring Harbor Laboratory)
  • EBioMedicine
  • Aging
  • GeroScience

Best Publications

  • Clearance of p16 Ink4a -positive senescent cells delays ageing-associated disorders

    Darren J. Baker;Tobias Wijshake;Tamar Tchkonia;Nathan K. LeBrasseur

  • The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

    Yi-Yi Zhu;Tamara Tchkonia;Tamar Pirtskhalava;Adam C Gower

  • Senolytics improve physical function and increase lifespan in old age

    Ming Xu;Ming Xu;Tamar Pirtskhalava;Joshua N. Farr;Bettina M. Weigand;Bettina M. Weigand

  • Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.

    Tamara Tchkonia;Yi Zhu;Jan van Deursen;Judith Campisi

  • Cellular senescence mediates fibrotic pulmonary disease

    Marissa J. Schafer;Thomas A. White;Koji Iijima;Andrew J. Haak

  • Fat tissue, aging, and cellular senescence

    Tamara Tchkonia;Dean E. Morbeck;Thomas Von Zglinicki;Jan Van Deursen

  • Cellular Senescence: A Translational Perspective.

    James L. Kirkland;Tamara Tchkonia

  • Targeting cellular senescence prevents age-related bone loss in mice

    Joshua N Farr;Ming Xu;Megan M Weivoda;David G Monroe

  • Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.

    Yi Zhu;Tamara Tchkonia;Heike Fuhrmann-Stroissnigg;Haiming M. Dai

  • Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.

    La Tonya J. Hickson;Larissa G.P. Langhi Prata;Shane A. Bobart;Tamara K. Evans

  • Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.

    Jamie N. Justice;Anoop M. Nambiar;Tamar Tchkonia;Nathan K. LeBrasseur

  • Cellular senescence drives age-dependent hepatic steatosis.

    Mikolaj Ogrodnik;Satomi Miwa;Tamar Tchkonia;Dina Tiniakos;Dina Tiniakos

  • Senolytic drugs: from discovery to translation.

    James L. Kirkland;Tamar Tchkonia

  • Fisetin is a senotherapeutic that extends health and lifespan

    Matthew J. Yousefzadeh;Yi Zhu;Sara J. McGowan;Luise Angelini

  • Mechanisms and Metabolic Implications of Regional Differences among Fat Depots

    Tamara Tchkonia;Thomas Thomou;Yi Zhu;Iordanes Karagiannides

  • JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

    Ming Xu;Tamara Tchkonia;Husheng Ding;Mikolaj Ogrodnik;Mikolaj Ogrodnik

  • Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

    Carolyn M. Roos;Bin Zhang;Allyson K. Palmer;Mikolaj B. Ogrodnik;Mikolaj B. Ogrodnik

  • Identification of HSP90 inhibitors as a novel class of senolytics

    Heike Fuhrmann-Stroissnigg;Yuan Yuan Ling;Jing Zhao;Sara J. McGowan

  • New agents that target senescent cells: the flavone, fisetin, and the BCL-X L inhibitors, A1331852 and A1155463.

    Yi Zhu;Ewald J. Doornebal;Tamar Pirtskhalava;Nino Giorgadze

  • Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat

    Tim J. Schulz;Tian Lian Huang;Thien T. Tran;Hongbin Zhang

Frequent Co-Authors

Marco Demaria
Marco Demaria University Medical Center Groningen
João F. Passos
João F. Passos Mayo Clinic
Jennifer H. Elisseeff
Jennifer H. Elisseeff Johns Hopkins University
Thomas A. White
Thomas A. White Mayo Clinic
Thomas von Zglinicki
Thomas von Zglinicki Newcastle University
Stephen B. Kritchevsky
Stephen B. Kritchevsky Wake Forest University
Eduardo N. Chini
Eduardo N. Chini Mayo Clinic

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in healthcare careers beyond traditional medical school, there are a variety of flexible online degree options to explore. Online nursing programs are a popular choice, offering future healthcare professionals the chance to study while balancing work or family commitments.

With healthcare costs rising, affordability is a top concern. Many reputable schools offer affordable online nursing programs designed to make education more accessible. If you’re aiming for advanced practice roles, consider nurse practitioner programs that combine rigorous training with the flexibility of online learning.

For registered nurses wishing to advance their credentials, the cheapest rn to bsn program options can help you earn your bachelor’s degree without a large financial burden. Those interested in research or academic careers can pursue phd nursing education online, unlocking new leadership roles and the chance to influence healthcare policy.

Whether you’re just starting in healthcare or seeking advanced qualifications, these online pathways can open doors to rewarding and impactful careers.

Best Scientists Citing Tamar Tchkonia

Trending Scientists