Gijsbertus T. J. van der Horst

What is he best known for?

The fields of study he is best known for:

• Gene
• DNA
• Enzyme

His primary areas of investigation include Cell biology, DNA repair, DNA damage, Genetics and Period Circadian Proteins. His studies in Cell biology integrate themes in fields like Cryptochrome, Circadian rhythm, Interkinesis, Regulation of gene expression and Meiotic cohesin complex. His Cryptochrome study integrates concerns from other disciplines, such as ARNTL Transcription Factors and Photolyase.

His primary area of study in DNA repair is in the field of Nucleotide excision repair. His biological study spans a wide range of topics, including Cancer research, Progeria and Ageing. His Period Circadian Proteins study combines topics in areas such as Transcription factor and CLOCK Proteins.

His most cited work include:

• Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. (1093 citations)
• A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis (538 citations)
• The Cryptochromes: Blue Light Photoreceptors in Plants and Animals (502 citations)

What are the main themes of his work throughout his whole career to date?

Gijsbertus T. J. van der Horst focuses on Nucleotide excision repair, Cell biology, Genetics, DNA repair and Circadian rhythm. His Nucleotide excision repair research includes themes of Carcinogenesis, Molecular biology and Xeroderma pigmentosum. His Xeroderma pigmentosum research includes elements of Mutation and Cancer research.

His Cell biology research is multidisciplinary, incorporating perspectives in Gene expression, Cellular differentiation, Period Circadian Proteins, Regulation of gene expression and CLOCK Proteins. He usually deals with DNA repair and limits it to topics linked to DNA damage and Gene, Cancer, Ageing and Immunosuppression. Gijsbertus T. J. van der Horst's looking at Circadian rhythm as part of his Endocrinology and Internal medicine and Circadian rhythm study.

He most often published in these fields:

• Nucleotide excision repair (33.33%)
• Cell biology (32.26%)
• Genetics (31.18%)

What were the highlights of his more recent work (between 2009-2020)?

• Circadian rhythm (29.03%)
• Circadian clock (22.58%)
• Internal medicine (23.66%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Circadian rhythm, Circadian clock, Internal medicine, Endocrinology and DNA damage. His research integrates issues of Melatonin, CRISPR, Carcinogenesis and Cell biology in his study of Circadian rhythm. His Cryptochrome study in the realm of Circadian clock interacts with subjects such as Variation.

His study in the field of Bone remodeling, Period and CLOCK is also linked to topics like Premature aging. His work carried out in the field of DNA damage brings together such families of science as Messenger RNA, Transfection, DNA repair and Photobiology. His Nucleotide excision repair and Cockayne syndrome study in the realm of DNA repair connects with subjects such as Sensorineural hearing loss.

Between 2009 and 2020, his most popular works were:

• The Cryptochromes: Blue Light Photoreceptors in Plants and Animals (502 citations)
• Accelerated Age-Related Cognitive Decline and Neurodegeneration, Caused by Deficient DNA Repair (82 citations)
• The Clock Genes Period 2 and Cryptochrome 2 Differentially Balance Bone Formation (72 citations)

In his most recent research, the most cited papers focused on:

• Gene
• DNA
• Enzyme

Gijsbertus T. J. van der Horst mainly investigates DNA damage, Circadian clock, Cell biology, Circadian rhythm and Cryptochrome. Nucleotide excision repair is the focus of his DNA damage research. His research investigates the connection between Cell biology and topics such as Cell cycle that intersect with issues in CLOCK.

Gijsbertus T. J. van der Horst has researched Circadian rhythm in several fields, including Regulator, Endogeny, Energy homeostasis and Genotoxic Stress. His study looks at the relationship between Cryptochrome and topics such as Evolutionary biology, which overlap with DNA repair. In the subject of general DNA repair, his work in Photolyase is often linked to Magnetoreception, thereby combining diverse domains of study.