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Molecular Biology

D-Index
61
Citations
14001
World Ranking
1905
National Ranking
50

Overview

Harry van Steeg is affiliated with the Centre for Health Protection in China and has contributed to several fields including biochemistry, genetics, molecular biology, and medicine. Their research spans multiple subfields such as molecular biology, physiology, aging, endocrine and autonomic systems, and public health, environmental and occupational health.

Their work addresses main topics including DNA repair mechanisms, genetics, aging and longevity in model organisms, circadian rhythm and melatonin, diet and metabolism studies, mitochondrial function and pathology, and organ donation and transplantation along with transplantation techniques and outcomes.

Van Steeg has authored papers published in a variety of scientific journals. Key publications include:

  • Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice, 2021, Aging Cell
  • Protein and calorie restriction may improve outcomes in living kidney donors and kidney transplant recipients, 2020, Aging
  • The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside, 2022, Frontiers in Aging
  • High protein intake causes gene-length-dependent transcriptional decline, shortens lifespan and accelerates ageing in progeroid DNA repair-deficient mice, 2025, npj Metabolic Health and Disease
  • Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside, 2022, Frontiers in Aging

Their frequent co-authors include Jan H.J. Hoeijmakers, Martijn E.T. Dollé, María B. Birkisdóttir, Renata M. C. Brandt, and Sander Barnhoorn.

Van Steeg's research has been featured in multiple publication venues with several contributions to Frontiers in Aging, Aging Cell, Aging, npj Metabolic Health and Disease, and Archives of Toxicology.

Best Publications

  • An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

    Marco Demaria;Naoko Ohtani;Sameh A Youssef;Francis Rodier

  • Aging and Genome Maintenance: Lessons from the Mouse?

    Paul Hasty;Judith Campisi;Judith Campisi;Jan Hoeijmakers;Harry van Steeg

  • Premature aging in mice deficient in DNA repair and transcription

    Jan de Boer;Jaan Olle Olle Andressoo;Jan de Wit;Jan Huijmans

  • Defective Transcription-Coupled Repair in Cockayne Syndrome B Mice Is Associated with Skin Cancer Predisposition

    Gijsbertus T.J van der Horst;Harry van Steeg;Rob J.W Berg;Alain J van Gool

  • Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair

    Agatha Schwarz;Sonja Ständer;Mark Berneburg;Markus Böhm

  • Homologous and non-homologous recombination differentially affect DNA damage repair in mice

    Jeroen Essers;Harry van Steeg;Jan de Wit;Sigrid M.A. Swagemakers

  • Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

    W. P. Vermeij;M. E T Dollé;E. Reiling;D. Jaarsma

  • Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach.

    Lya G. Hernández;Harry van Steeg;Mirjam Luijten;Jan van Benthem

  • Xeroderma pigmentosum and the role of UV-induced DNA damage in skin cancer.

    Harry van Steeg;Kenneth H Kraemer

  • Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome

    Ingrid van der Pluijm;George A Garinis;Renata M. C Brandt;Theo G. M. F Gorgels;Theo G. M. F Gorgels

  • Oxidative DNA damage and nucleotide excision repair.

    Joost P.M. Melis;Harry van Steeg;Mirjam Luijten

  • Prevention of UV radiation-induced immunosuppression by IL-12 is dependent on DNA repair.

    Agatha Schwarz;Akira Maeda;Kerstin Kernebeck;Harry van Steeg

  • Powerful Skin Cancer Protection by a CPD-Photolyase Transgene

    Judith Jans;Wouter Schul;Wouter Schul;Yurda-Gul Sert;Yvonne Rijksen

  • The Relationship Between Shift Work and Metabolic Risk Factors: A Systematic Review of Longitudinal Studies.

    Karin I. Proper;Daniëlla van de Langenberg;Wendy Rodenburg;Roel C.H. Vermeulen

  • Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms

    Björn Schumacher;Ingrid van der Pluijm;Michael J. Moorhouse;Theodore Kosteas

  • A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy

    Jan de Boer;Jan de Wit;Harry van Steeg;Rob J.W. Berg

  • Differential Contributions of Mammalian Rad54 Paralogs to Recombination, DNA Damage Repair, and Meiosis

    Joanna Wesoly;Sheba Agarwal;Stefan Sigurdsson;Wendy Bussen

  • Disruption of Mouse SNM1 Causes Increased Sensitivity to the DNA Interstrand Cross-Linking Agent Mitomycin C

    Mies L. G. Dronkert;Jan de Wit;Miranda Boeve;M. Luisa Vasconcelos

  • Chronically Alternating Light Cycles Increase Breast Cancer Risk in Mice

    Kirsten C.G. Van Dycke;Kirsten C.G. Van Dycke;Wendy Rodenburg;Conny T.M. van Oostrom;Linda W.M. van Kerkhof

  • Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

    George A Garinis;Lieneke M Uittenboogaard;Heike Stachelscheid;Maria Fousteri

Frequent Co-Authors

Jan H.J. Hoeijmakers
Jan H.J. Hoeijmakers Erasmus University Rotterdam
Gijsbertus T. J. van der Horst
Gijsbertus T. J. van der Horst Erasmus University Rotterdam
Jan Vijg
Jan Vijg Albert Einstein College of Medicine
Laura J. Niedernhofer
Laura J. Niedernhofer University of Minnesota
Errol C. Friedberg
Errol C. Friedberg The University of Texas Southwestern Medical Center
Jan de Boer
Jan de Boer Antoni van Leeuwenhoek Hospital
Leon H.F. Mullenders
Leon H.F. Mullenders Leiden University
Jeroen Essers
Jeroen Essers Erasmus University Rotterdam
Thomas Schwarz
Thomas Schwarz Boston Children's Hospital

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