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Overview

William D. Middleton is affiliated with Washington University in St. Louis in the United States. Their primary field of study is Medicine, with a focus on several subfields including Surgery, Immunology, Radiology, Nuclear Medicine and Imaging, Infectious Diseases, and Pulmonary and Respiratory Medicine.

The research topics covered by Middleton prominently include:

  • SARS-CoV-2 and COVID-19 Research
  • Immunotherapy and Immune Responses
  • Thyroid Cancer Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Radiology practices and education
  • Influenza Virus Research Studies

Middleton has contributed to multiple recent papers, emphasizing immunology and infectious diseases with an emphasis on SARS-CoV-2 mRNA vaccines and related immune responses. Key publications include:

  • "SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses" (2021, Nature)
  • "Germinal centre-driven maturation of B cell response to mRNA vaccination" (2022, Nature)
  • "SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans" (2021, Cell)
  • "SARS-CoV-2 Omicron boosting induces de novo B cell response in humans" (2023, Nature)
  • "Management of Incidentally Detected Gallbladder Polyps: Society of Radiologists in Ultrasound Consensus Conference Recommendations" (2022, Radiology)

Their frequent co-authors include:

  • Sharlene A. Teefey
  • Jackson S. Turner
  • Rachel M. Presti
  • Ali H. Ellebedy
  • Aaron J. Schmitz

William D. Middleton has published extensively in well-known venues, with repeated contributions to:

  • Journal of Ultrasound in Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Roentgenology
  • Ultrasound Quarterly
  • Abdominal Radiology

Best Publications

  • The Outcome and Repair Integrity of Completely Arthroscopically Repaired Large and Massive Rotator Cuff Tears

    Leesa M. Galatz;Craig M. Ball;Sharlene A. Teefey;William D. Middleton

  • Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement

    Mary C. Frates;Carol B. Benson;J. William Charboneau;Edmund S. Cibas

  • ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee

    Franklin N. Tessler;William D. Middleton;Edward G. Grant;Jenny K. Hoang

  • The demographic and morphological features of rotator cuff disease. A comparison of asymptomatic and symptomatic shoulders.

    Ken Yamaguchi;Konstantinos Ditsios;William D. Middleton;Charles F. Hildebolt

  • SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses.

    Jackson S. Turner;Jane A. O’Halloran;Elizaveta Kalaidina;Wooseob Kim

  • Natural history of asymptomatic rotator cuff tears: a longitudinal analysis of asymptomatic tears detected sonographically.

    Ken Yamaguchi;A.Marc Tetro;Oren Blam;Bradley A. Evanoff

  • Detection and quantification of rotator cuff tears. Comparison of ultrasonographic, magnetic resonance imaging, and arthroscopic findings in seventy-one consecutive cases.

    Sharlene A. Teefey;David A. Rubin;William D. Middleton;Charles F. Hildebolt

  • Ultrasonography of the rotator cuff. A comparison of ultrasonographic and arthroscopic findings in one hundred consecutive cases

    Sharlene Teefey;S. Hasan;William Middleton;Mihir Patel

  • Thyroid Ultrasound Reporting Lexicon: White Paper of the ACR Thyroid Imaging, Reporting and Data System (TIRADS) Committee

    Edward G. Grant;Franklin N. Tessler;Jenny K. Hoang;Jill E. Langer

  • Symptomatic Progression of Asymptomatic Rotator Cuff Tears: A Prospective Study of Clinical and Sonographic Variables

    Nathan A. Mall;H. Mike Kim;Jay D. Keener;Karen Steger-May

  • Factors Affecting Healing Rates After Arthroscopic Double-Row Rotator Cuff Repair

    Robert Z. Tashjian;Anthony M. Hollins;Hyun-Min Mike Kim;Sharlene A. Teefey

  • Fat-containing lesions of the liver: radiologic-pathologic correlation.

    Srinivasa R. Prasad;Hanlin Wang;Humberto Rosas;Christine O. Menias

  • Managing Incidental Thyroid Nodules Detected on Imaging: White Paper of the ACR Incidental Thyroid Findings Committee

    Jenny K. Hoang;Jill E. Langer;William D. Middleton;Carol C. Wu

  • Testicular microlithiasis: imaging appearances and pathologic correlation.

    Mark L. Backus;Laurence A. Mack;William D. Middleton;Bernard F. King

  • Ultrasonographic evaluation of the rotator cuff and biceps tendon.

    W. D. Middleton;W. R. Reinus;W. G. Totty;C. L. Melson

  • Location and initiation of degenerative rotator cuff tears: An analysis of three hundred and sixty shoulders

    H. Mike Kim;Nirvikar Dahiya;Sharlene A. Teefey;William D. Middleton

  • Detection of primary hepatic malignancy in liver transplant candidates: prospective comparison of CT, MR imaging, US, and PET.

    Sharlene A. Teefey;Charles C. Hildeboldt;Farrokh Dehdashti;Barry A. Siegel

  • Cigarette smoking increases the risk for rotator cuff tears.

    Keith M. Baumgarten;David Gerlach;Leesa M. Galatz;Sharlene A. Teefey

  • A Prospective Evaluation of Survivorship of Asymptomatic Degenerative Rotator Cuff Tears

    Jay D. Keener;Leesa M. Galatz;Sharlene A. Teefey;William D. Middleton

  • Color Doppler ultrasound of the normal testis.

    W D Middleton;D A Thorne;G L Melson

Frequent Co-Authors

James S. Hyde
James S. Hyde Medical College of Wisconsin
Elspeth M. McDougall
Elspeth M. McDougall University of British Columbia
Ali H. Ellebedy
Ali H. Ellebedy Washington University in St. Louis
Nathaniel J. Soper
Nathaniel J. Soper Northwestern University
Steven M. Strasberg
Steven M. Strasberg Washington University in St. Louis
Barry A. Siegel
Barry A. Siegel Washington University in St. Louis
Gerald L. Andriole
Gerald L. Andriole Washington University in St. Louis
Marion G. Peters
Marion G. Peters University of California, San Francisco
Pei-Yong Shi
Pei-Yong Shi GlaxoSmithKline (United Kingdom)
Fatima Amanat
Fatima Amanat Icahn School of Medicine at Mount Sinai

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