What is he best known for?
The fields of study he is best known for:
Leon H.F. Mullenders mainly focuses on Molecular biology, DNA repair, Xeroderma pigmentosum, Nucleotide excision repair and DNA.
The study incorporates disciplines such as Transcription factor II B, General transcription factor, RNA polymerase II, Computational biology and Transcription factor II D in addition to Molecular biology.
His DNA damage research extends to DNA repair, which is thematically connected.
In his study, which falls under the umbrella issue of Xeroderma pigmentosum, DNA polymerase eta, Proliferating cell nuclear antigen, Cancer research and Carcinogenesis is strongly linked to Mutation.
Leon H.F. Mullenders focuses mostly in the field of Nucleotide excision repair, narrowing it down to topics relating to Carcinogen and, in certain cases, Medical physics and Intensive care medicine.
Pyrimidine dimer and DNA glycosylase are the core of his DNA study.
His most cited work include:
- The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. (478 citations)
- UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer (401 citations)
- Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes. (288 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Molecular biology, DNA repair, Nucleotide excision repair, DNA and DNA damage.
His Molecular biology research includes themes of Mutation, Transcription, Mutagenesis, Gene and Pyrimidine dimer.
His DNA repair study incorporates themes from Oligonucleotide and Cell biology.
His research in Nucleotide excision repair intersects with topics in Chromatin, Cancer research, Xeroderma pigmentosum and Carcinogen.
The Xeroderma pigmentosum study which covers Carcinogenesis that intersects with Apoptosis.
His study in the fields of Nuclear matrix under the domain of DNA overlaps with other disciplines such as Nucleoid.
He most often published in these fields:
- Molecular biology (55.12%)
- DNA repair (51.97%)
- Nucleotide excision repair (45.67%)
What were the highlights of his more recent work (between 2003-2020)?
- Cell biology (21.26%)
- Nucleotide excision repair (45.67%)
- DNA repair (51.97%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cell biology, Nucleotide excision repair, DNA repair, DNA damage and Molecular biology.
Leon H.F. Mullenders is interested in Cockayne syndrome, which is a branch of Nucleotide excision repair.
In his research, Gene mutation is intimately related to Epidermis, which falls under the overarching field of DNA repair.
His DNA damage study is related to the wider topic of DNA.
His DNA research includes elements of Mutagenesis and Interphase.
The Molecular biology study combines topics in areas such as Global genome nucleotide-excision repair, Polymerase, Apoptosis, Chromatin and Comet assay.
Between 2003 and 2020, his most popular works were:
- The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells (180 citations)
- Assessing cancer risks of low-dose radiation (150 citations)
- Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity (109 citations)
In his most recent research, the most cited papers focused on:
Leon H.F. Mullenders mostly deals with DNA damage, Cell biology, Molecular biology, Nucleotide excision repair and DNA.
His studies deal with areas such as HMG-box, DDB1, DNA ligase and DNA repair as well as DNA damage.
His DNA repair study is concerned with the field of Gene as a whole.
His Molecular biology research integrates issues from Signal transduction, Premature chromosome condensation and Mutagenesis.
His Nucleotide excision repair research incorporates themes from Replication protein A, Cancer research, Xeroderma pigmentosum, Carcinogenesis and Ubiquitin ligase.
His work on Pyrimidine dimer and Comet assay is typically connected to Nucleoid as part of general DNA study, connecting several disciplines of science.
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