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Biology and Biochemistry

D-Index
54
Citations
9390
World Ranking
15733
National Ranking
382

Overview

Firouz Darroudi is affiliated with Leiden University Medical Center in the Netherlands. Their research spans multiple fields, primarily focusing on medicine as well as agricultural and biological sciences.

The scientist's work involves several interconnected topics, including:

  • Telomeres, Telomerase, and Senescence
  • Radiation Therapy and Dosimetry
  • Plant Genetic and Mutation Studies
  • Carcinogens and Genotoxicity Assessment
  • Genetically Modified Organisms Research
  • Effects and Risks of Endocrine Disrupting Chemicals

Darroudi has contributed to research in various subfields such as plant science, physiology, pulmonary and respiratory medicine, cancer research, and health, toxicology, and mutagenesis.

Their recent publications include:

  • The Role of Telomerase in Radiation-Induced Genomic Instability, 2020, Radiation Research
  • Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead, 2020, UNC Libraries

Frequent co-authors in their publications include Otilia Nuta, Kai Rothkamm, William H. Goodson, Leroy Lowe, and David O. Carpenter.

Darroudi's work has appeared mainly in the venues Radiation Research and UNC Libraries, reflecting their interdisciplinary focus in both radiation biology and environmental health sciences.

Best Publications

  • How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.

    David Kirkland;Stefan Pfuhler;David Tweats;Marilyn Aardema

  • Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge.

    S Knasmüller;V Mersch-Sundermann;S Kevekordes;F Darroudi

  • Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens.

    Siegfried Knasmüller;Wolfram Parzefall;Ratna Sanyal;Sonja Ecker

  • Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents.

    Volker Mersch-Sundermann;Siegfried Knasmüller;Xin Jiang Wu;Firouz Darroudi

  • Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: The challenge ahead

    William H Goodson;Leroy Lowe;David O Carpenter;Michael Gilbertson

  • Review of retrospective dosimetry techniques for external ionising radiation exposures

    E. A. Ainsbury;E. Bakhanova;J. F. Barquinero;M. Brai;M. Brai

  • Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens

    A.T. Natarajan;F. Darroudi

  • Chromosomal aberrations in human lymphocytes induced in vitro by very low doses of X-rays.

    D. C. Lloyd;A. A. Edwards;A. Leonard;G. L. Deknudt

  • Frequencies of X-ray-induced chromosome translocations in human peripheral lymphocytes as detected by in situ hybridization using chromosome-specific DNA libraries.

    A.T. Natarajan;R.C. Vyas;F. Darroudi;S. Vermeulen

  • Causes of genome instability: the effect of low dose chemical exposures in modern society

    Sabine A S Langie;Gudrun Koppen;Daniel Desaulniers;Fahd Al-Mulla

  • Khat (Catha edulis) consumption causes genotoxic effects in humans.

    Fekadu Kassie;Firouz Darroudi;Michael Kundi;Rolf Schulte-Hermann

  • International study of factors affecting human chromosome translocations

    Alice J. Sigurdson;Mina Ha;Mina Ha;Michael Hauptmann;Michael Hauptmann;Parveen Bhatti

  • Review of translocations detected by FISH for retrospective biological dosimetry applications

    A. A. Edwards;C. Lindholm;F. Darroudi;G. Stephan

  • Chromosomal aberrations in peripheral blood lymphocytes from native Andean women and children from Northwestern Argentina exposed to arsenic in drinking water

    Fernando N. Dulout;Claudia A. Grillo;Analía I. Seoane;Carlos R. Maderna

  • Inhibition of the genotoxic effects of heterocyclic amines in human derived hepatoma cells by dietary bioantimutagens

    Ratna Sanyal;Firouz Darroudi;Wolfram Parzefall;Minako Nagao

  • Cytological characterization of Chinese hamster ovary X-ray-sensitive mutant cells xrs 5 and xrs 6: I. Induction of chromosomal aberrations by X-irradiation and its modulation with 3-aminobenzamide and caffeine

    F. Darroudi;A.T. Natarajan

  • Discrimination between complete and incomplete chromosome exchanges in X-irradiated human lymphocytes using FISH with pan-centromeric and chromosome specific DNA probes in combination with telomeric PNA probe.

    J. Fomina;F. Darroudi;J. J. W. A. Boei;A. T. Natarajan

  • 137Cesium-induced chromosome aberrations analyzed by fluorescence in situ hybridization: eight years follow up of the Goiânia radiation accident victims

    A.T. Natarajan;S.J. Santos;F. Darroudi;V. Hadjidikova

  • The nature and repair of DNA lesions that lead to chromosomal aberrations induced by ionizing radiations

    A.T. Natarajan;F. Darroudi;L.H.F. Mullenders;M. Meijers

  • Use Of Metabolically Competent Human Hepatoma Cells of The Detection Of Mutagens And Antimutagens

    Siegfried Knasmuller;Wolfram Parzefall;Ratna Sanyal;Sonja Ecker

Frequent Co-Authors

Adayapalam T. Natarajan
Adayapalam T. Natarajan Leiden University
Laure Sabatier
Laure Sabatier University of Paris-Saclay
Leon H.F. Mullenders
Leon H.F. Mullenders Leiden University
Siegfried Knasmüller
Siegfried Knasmüller Medical University of Vienna
Hansruedi Glatt
Hansruedi Glatt Federal Institute for Risk Assessment
Sankar Mitra
Sankar Mitra Houston Methodist
Nicolaas G. J. Jaspers
Nicolaas G. J. Jaspers Erasmus University Rotterdam
Paul H.M. Lohman
Paul H.M. Lohman Leiden University Medical Center
Hans Joenje
Hans Joenje VU University Medical Center

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