D-Index & Metrics Best Publications
William G. Thilly

William G. Thilly

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 58 Citations 11,740 210 World Ranking 1406 National Ranking 716

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His scientific interests lie mostly in Molecular biology, Genetics, Mutant, Mutation and Cell culture. His Molecular biology study combines topics in areas such as Lymphoblast, Biochemistry, DNA, Point mutation and DNA polymerase II. William G. Thilly has researched Lymphoblast in several fields, including Somatic cell, Gene mutation, Thymidine, Environmental chemistry and Ploidy.

His DNA research incorporates themes from DNA Mutational Analysis and Mitochondrial DNA. He studies Hypoxanthine-guanine phosphoribosyltransferase which is a part of Mutant. His Cell culture research is multidisciplinary, incorporating elements of Heterozygote advantage, Ethyl methanesulfonate, Locus and Cell biology.

His most cited work include:

  • A strategy to discover genes that carry multi-allelic or mono-allelic risk for common diseases: a cohort allelic sums test (CAST). (413 citations)
  • Fidelity of DNA polymerases in DNA amplification. (408 citations)
  • An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. (393 citations)

What are the main themes of his work throughout his whole career to date?

William G. Thilly mainly investigates Molecular biology, Genetics, Mutant, Biochemistry and Lymphoblast. His Molecular biology research is multidisciplinary, incorporating perspectives in Cell culture, Mutation, Point mutation, DNA and Exon. His Point mutation research is multidisciplinary, relying on both Capillary electrophoresis and DNA sequencing.

His study in Mutation, Gene, Polymerase chain reaction, Genome and Somatic cell are all subfields of Genetics. The study incorporates disciplines such as DNA Mutational Analysis, Gene mutation and Mitochondrial DNA in addition to Mutant. His Lymphoblast study combines topics in areas such as Mutagen, Salmonella, Ethyl methanesulfonate, Locus and Ploidy.

He most often published in these fields:

  • Molecular biology (40.83%)
  • Genetics (27.50%)
  • Mutant (22.50%)

What were the highlights of his more recent work (between 2002-2020)?

  • Stem cell (8.75%)
  • Genetics (27.50%)
  • Molecular biology (40.83%)

In recent papers he was focusing on the following fields of study:

William G. Thilly focuses on Stem cell, Genetics, Molecular biology, Point mutation and Cell biology. His study in Stem cell is interdisciplinary in nature, drawing from both Cancer research, Carcinogenesis, Juvenile, Pathology and Cell type. His Gene and Allele study in the realm of Genetics connects with subjects such as Purine analogue.

His research integrates issues of DNA Mutational Analysis, Somatic cell, Mutant, DNA and Cell nucleus in his study of Molecular biology. His Mutant research focuses on DNA sequencing and how it connects with KRAS. His Point mutation research incorporates elements of genomic DNA, Polymerase chain reaction and Mitochondrial DNA.

Between 2002 and 2020, his most popular works were:

  • A strategy to discover genes that carry multi-allelic or mono-allelic risk for common diseases: a cohort allelic sums test (CAST). (413 citations)
  • Have environmental mutagens caused oncomutations in people (96 citations)
  • Origins of human mitochondrial point mutations as DNA polymerase γ-mediated errors (95 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His scientific interests lie mostly in Genetics, Point mutation, Stem cell, Molecular biology and Carcinogenesis. Allele, Polymerase chain reaction, Single-nucleotide polymorphism, DNA and Genetic variability are the primary areas of interest in his Genetics study. His studies in DNA integrate themes in fields like Nucleic Acid Denaturation and GC-content.

The various areas that William G. Thilly examines in his Point mutation study include Cancer and Environmental Carcinogenesis. His Molecular biology research integrates issues from Mutant, Mitochondrial DNA and DNA polymerase. The Mutant study combines topics in areas such as Mutation and DNA sequencing.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Fidelity of DNA polymerases in DNA amplification.

Phouthone Keohavong;William G. Thilly.
Proceedings of the National Academy of Sciences of the United States of America (1989)

680 Citations

A strategy to discover genes that carry multi-allelic or mono-allelic risk for common diseases: a cohort allelic sums test (CAST).

Stephan Morgenthaler;William G. Thilly.
Mutation Research (2007)

663 Citations

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

Alexandra Kat;William G. Thilly;Woei Horng Fang;Matthew J. Longley.
Proceedings of the National Academy of Sciences of the United States of America (1993)

550 Citations

Mismatch amplification mutation assay (MAMA): application to the c-H-ras gene.

Rita S. Cha;Helmut Zarbl;Phouthone Keohavong;William G. Thilly.
Genome Research (1992)

525 Citations

Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates

Emma E. Furth;William G. Thilly;Bruce W. Penman;Howard L. Liber.
Analytical Biochemistry (1981)

372 Citations

High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection

Hilary A. Coller;Konstantin Khrapko;Natalya D. Bodyak;Ekaterina Nekhaeva.
Nature Genetics (2001)

349 Citations

Mutation assay at the thymidine kinase locus in diploid human lymphoblasts

Howard L. Liber;William G. Thilly.
Mutation Research (1982)

347 Citations

Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay.

Thomas R. Skopek;Howard L. Liber;Bruce W. Penman;William G. Thilly.
Biochemical and Biophysical Research Communications (1978)

291 Citations

Mutagenicity of soot and associated polycyclic aromatic hydrocarbons to Salmonella typhimurium.

Debra A. Kaden;Ronald A. Hites;William G. Thilly.
Cancer Research (1979)

265 Citations

Mitochondrial mutational spectra in human cells and tissues

Konstantin Khrapko;Hilary A. Coller;Paulo C. André;Xiao Cheng Li.
Proceedings of the National Academy of Sciences of the United States of America (1997)

231 Citations

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