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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
13099
World Ranking
16511
National Ranking
6837

Overview

James C. Willey is affiliated with the University of Toledo in the United States. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions to several subfields including Pulmonary and Respiratory Medicine, Molecular Biology, Cancer Research, Genetics, and Environmental Chemistry.

The scientist's work covers a range of main topics, including:

  • Cancer Genomics and Diagnostics
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • RNA modifications and cancer
  • Molecular Biology Techniques and Applications
  • Genetic factors in colorectal cancer
  • Aquatic Ecosystems and Phytoplankton Dynamics

James C. Willey has published numerous papers with frequent appearances in venues such as Cancer Research, Translation The University of Toledo Journal of Medical Sciences, Genome Biology, Annals of Emergency Medicine, and Nature Biotechnology.

Some of the recent papers include:

  • "Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology," 2021, Nature Biotechnology
  • "Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing," 2021, Nature Biotechnology
  • "Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer," 2022, Nature Genetics
  • "A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency," 2021, Genome Biology
  • "The importance of low-dose CT screening to identify emphysema in asymptomatic participants with and without a prior diagnosis of COPD," 2021, Clinical Imaging

The scientist has collaborated frequently with co-authors including Erin L. Crawford, Daniel J. Craig, Rebecca Kusko, Todd Richmond, and Natalia Novoradovskaya.

Best Publications

  • The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

    Leming Shi;Laura H. Reid;Wendell D. Jones;Richard Shippy

  • The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

    Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne

  • A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

    Zhenqiang Su;Paweł P. Łabaj;Sheng Li;Jean Thierry-Mieg

  • Evaluation of DNA microarray results with quantitative gene expression platforms.

    Roger D Canales;Yuling Luo;James C Willey;Bradley Austermiller

  • The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

    Leming Shi;Wendell D. Jones;Roderick V. Jensen;Stephen C. Harris

  • Bombesin and the C-terminal tetradecapeptide of gastrin-releasing peptide are growth factors for normal human bronchial epithelial cells

    J.C. Willey;J.F. Lechner;C.C. Harris

  • Differential DNA sequence deletions from chromosomes 3, 11, 13, and 17 in squamous-cell carcinoma, large-cell carcinoma, and adenocarcinoma of the human lung.

    A Weston;J C Willey;R Modali;H Sugimura

  • Transformation of human bronchial epithelial cells transfected by Harvey ras oncogene

    George H. Yoakum;John F. Lechner;Edward W. Gabrielson;Brent E. Korba

  • Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction

    James C. Willey

  • Variation in transcriptional regulation of cyclin dependent kinase inhibitor p21waf1/cip1 among human bronchogenic carcinomas

    Michael W Harr;Timothy G Graves;Erin L Crawford;Kristy A Warner

  • ABCC5, ERCC2, XPA and XRCC1 transcript abundance levels correlate with cisplatin chemoresistance in non-small cell lung cancer cell lines

    David A Weaver;Erin L Crawford;Kristy A Warner;Fadel Elkhairi

  • Using RNA sample titrations to assess microarray platform performance and normalization techniques

    Richard Shippy;Stephanie Fulmer-Smentek;Roderick V Jensen;Wendell D Jones

  • Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells

    N. Avissar;J. N. Finkelstein;S. Horowitz;J. C. Willey

  • Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology

    Ira W. Deveson;Binsheng Gong;Kevin Lai;Jennifer S. LoCoco

  • Immortalization of normal human bronchial epithelial cells by human papillomaviruses 16 or 18.

    James C. Willey;Alberec Broussoud;Ambereen Sleemi;William P. Bennett

  • Quantitative RT-PCR measurement of cytochromes p450 1A1, 1B1, and 2B7, microsomal epoxide hydrolase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers

    James C. Willey;Erin L. Coy;Mark W. Frampton;Alfonso Torres

  • Pathobiological Effects of Acrolein in Cultured Human Bronchial Epithelial Cells

    Roland C. Grafström;Jeannette M. Dypbukt;James C. Willey;Kristina Sundqvist

  • Stable low-level expression of p21WAF1/CIP1 in A549 human bronchogenic carcinoma cell line-derived clones down-regulates E2F1 mRNA and restores cell proliferation control.

    Timothy G Graves;Michael W Harr;Erin L Crawford;James C Willey

  • Xenobiotic metabolism enzyme gene expression in human bronchial epithelial and alveolar macrophage cells.

    James C. Willey;Erin Coy;Colleen Brolly;Mark J. Utell

  • Expression measurement of many genes simultaneously by quantitative RT-PCR using standardized mixtures of competitive templates.

    James C. Willey;Erin L. Crawford;Clara M. Jackson;David A. Weaver

Frequent Co-Authors

Curtis C. Harris
Curtis C. Harris National Institutes of Health
Leming Shi
Leming Shi Fudan University
Quan Zhen Li
Quan Zhen Li The University of Texas Southwestern Medical Center
Weida Tong
Weida Tong National Center for Toxicological Research
Mei Lu
Mei Lu Henry Ford Health System
Tom K. Hei
Tom K. Hei Columbia University
Huixiao Hong
Huixiao Hong United States Food and Drug Administration
Wenzhong Xiao
Wenzhong Xiao Harvard University
Pierre P. Massion
Pierre P. Massion Vanderbilt University Medical Center

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