His primary scientific interests are in Immunology, Autoimmune disease, Lupus erythematosus, Autoimmunity and Autoantibody. His Immunology study frequently draws connections between adjacent fields such as Systemic lupus erythematosus. His Autoimmune disease research includes elements of TLR7, DNA, Second messenger system and Anti-SSA/Ro autoantibodies.
His Lupus erythematosus study combines topics from a wide range of disciplines, such as Human leukocyte antigen and Genotype, Single-nucleotide polymorphism, Allele, Haplotype. His studies in Autoimmunity integrate themes in fields like Mutation, Cancer research, Antigen and Chromosomal translocation. His Autoantibody research incorporates themes from Congenic, Enzyme activator, Interferon, Pathology and Lupus nephritis.
The scientist’s investigation covers issues in Immunology, Autoantibody, Autoimmunity, Autoimmune disease and Systemic lupus erythematosus. His Immunology study frequently draws parallels with other fields, such as Lupus nephritis. His Lupus nephritis study also includes fields such as
His Autoantibody research is multidisciplinary, incorporating elements of Immunoglobulin G, Internal medicine, Arthritis and Haplotype. His research in Autoimmune disease intersects with topics in Human leukocyte antigen and Anti-SSA/Ro autoantibodies. His Lupus erythematosus research includes themes of Single-nucleotide polymorphism and Rheumatology.
Quan Zhen Li spends much of his time researching Immunology, Autoimmunity, Autoantibody, Internal medicine and Computational biology. As part of his studies on Immunology, he often connects relevant subjects like Transforming growth factor. The study incorporates disciplines such as Systemic lupus erythematosus, Autoimmune disease, Downregulation and upregulation and B cell in addition to Autoimmunity.
His Autoimmune disease study integrates concerns from other disciplines, such as SNP array, Single-nucleotide polymorphism, Allele, Haplotype and Candidate gene. The Autoantibody study combines topics in areas such as Stromal cell, Conditional gene knockout, Adverse effect, Arachidonic acid and Toxicity. The various areas that Quan Zhen Li examines in his Computational biology study include Variant allele, Liquid biopsy and DNA sequencing.
His primary areas of study are Immunology, Autoimmunity, Autoantibody, Systemic lupus erythematosus and Autoimmune disease. His Antibody, Immunity, Immunosuppression and Serology investigations are all subjects of Immunology research. His work deals with themes such as B cell, Cell biology, Epigenetics, Retinoic acid and Mitophagy, which intersect with Autoimmunity.
His study in Autoantibody is interdisciplinary in nature, drawing from both Immune system, Immunotherapy, Classical complement pathway and Antigen. His studies deal with areas such as Omega 3 fatty acid intake, Docosahexaenoic acid and Interferon as well as Systemic lupus erythematosus. The various areas that he examines in his Autoimmune disease study include Lymphocyte, Complement system, Mitochondrion and Mitochondrial DNA.
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The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
Leming Shi;Laura H. Reid;Wendell D. Jones;Richard Shippy.
Nature Biotechnology (2006)
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob.
Nature Genetics (2008)
The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne.
Nature Biotechnology (2010)
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium
Zhenqiang Su;Paweł P. Łabaj;Sheng Li;Jean Thierry-Mieg.
Nature Biotechnology (2014)
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus.
Srividya Subramanian;Katalin Tus;Quan Zhen Li;Andrew Wang.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
Daxing Gao;Tuo Li;Xiao Dong Li;Xiang Chen.
Proceedings of the National Academy of Sciences of the United States of America (2015)
The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies
Leming Shi;Wendell D. Jones;Roderick V. Jensen;Stephen C. Harris.
BMC Bioinformatics (2008)
Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells
Jennifer Martinez;Larissa D. Cunha;Sunmin Park;Mao Yang.
A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.
Swapan K. Nath;Shizhong Han;Xana Kim-Howard;Jennifer A. Kelly.
Nature Genetics (2008)
Combined Deficiency of Proapoptotic Regulators Bim and Fas Results in the Early Onset of Systemic Autoimmunity
Jack Hutcheson;Jack Hutcheson;John C. Scatizzi;John C. Scatizzi;Akbar M. Siddiqui;G. Kenneth Haines.
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