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Immunology

D-Index
69
Citations
20801
World Ranking
2484
National Ranking
1190

Overview

Quan Zhen Li is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily focuses on the fields of immunology and microbiology, with a particular emphasis on immunology and rheumatology as subfields. The scientist has contributed to the understanding of T-cell and B-cell immunology, immune response and inflammation, immune cell function and interaction, as well as systemic lupus erythematosus research.

Li has published work in several notable venues, including:

  • The Journal of Immunology
  • Autoimmunity

Frequent coworkers in their research include Mridu Acharya, Fiona Raso, Sara Sagadiev, Emily Gilbertson, and Lauren Kadavy.

Among their recent papers are:

  • "B Cell αv Integrins Regulate TLR-Driven Autoimmunity," published in 2020 in The Journal of Immunology
  • "Subchronic intranasal lipopolysaccharide exposure induces pulmonary autoimmunity and glomerulonephritis in NZBWF1 mice," published in 2024 in Autoimmunity

The topics covered by these publications reflect their broader research interests, which include:

  • T-cell and B-cell immunology
  • Immune response and inflammation
  • Immune cell function and interaction
  • Systemic lupus erythematosus research

Quan Zhen Li's body of work contributes to ongoing investigations into immune system function and autoimmune diseases by exploring molecular and cellular mechanisms underlying immune responses and systemic autoimmunity.

Best Publications

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • A Tlr7 translocation accelerates systemic autoimmunity in murine lupus.

    Srividya Subramanian;Katalin Tus;Quan Zhen Li;Andrew Wang

  • Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

    Daxing Gao;Tuo Li;Xiao Dong Li;Xiang Chen

  • Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

    Jennifer Martinez;Larissa D. Cunha;Sunmin Park;Mao Yang

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.

    Swapan K. Nath;Shizhong Han;Xana Kim-Howard;Jennifer A. Kelly

  • Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease

    Aaron Burberry;Aaron Burberry;Naoki Suzuki;Naoki Suzuki;Jin Yuan Wang;Jin Yuan Wang;Rob Moccia;Rob Moccia

  • Combined Deficiency of Proapoptotic Regulators Bim and Fas Results in the Early Onset of Systemic Autoimmunity

    Jack Hutcheson;Jack Hutcheson;John C. Scatizzi;John C. Scatizzi;Akbar M. Siddiqui;G. Kenneth Haines

  • Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays

    Quan Li Zhen;Chun Xie;Tianfu Wu;Meggan Mackay

  • Autoimmunity is a hallmark of post-COVID syndrome

    Unknown

  • Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.

    Amr H Sawalha;Amr H Sawalha;Amr H Sawalha;Kenneth M Kaufman;Kenneth M Kaufman;Kenneth M Kaufman;Jennifer A Kelly;Adam J Adler

  • Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes

    Q. Z. Li;J. Zhou;A. E. Wandstrat;F. Carr-Johnson

  • Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice

    Marie Laure Santiago-Raber;Isabelle Dunand-Sauthier;Tianfu Wu;Quan Zhen Li

  • SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

    Amy M. Becker;Kathryn H. Dao;Bobby Kwanghoon Han;Roger Kornu

  • Risk factors for ANA positivity in healthy persons

    Quan Zhen Li;David R. Karp;Jiexia Quan;Valerie K. Branch

  • Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy.

    Shannon K. O'Neill;Andrew Getahun;Stephen B. Gauld;Kevin T. Merrell

  • Metabolic Disturbances Associated with Systemic Lupus Erythematosus

    Tianfu Wu;Chun Xie;Jie Han;Yujin Ye

  • Yaa autoimmune phenotypes are conferred by overexpression of TLR7

    Anna Marie Fairhurst;Sun Hee Hwang;Andrew Wang;Xiang Hong Tian

  • Evidence for intranasal antinuclear autoantibodies in patients with chronic rhinosinusitis with nasal polyps

    Bruce K. Tan;Quan Zhen Li;Lydia Suh;Atsushi Kato

  • Immune dysregulation in cancer patients developing immune-related adverse events.

    Shaheen Khan;Saad A. Khan;Xin Luo;Farjana J. Fattah

  • Opposing Impact of B Cell–Intrinsic TLR7 and TLR9 Signals on Autoantibody Repertoire and Systemic Inflammation

    Shaun W. Jackson;Nicole E. Scharping;Nikita S. Kolhatkar;Nikita S. Kolhatkar;Socheath Khim

  • A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases

    Jian Zhao;Jian Zhao;Jianyang Ma;Yun Deng;Yun Deng;Jennifer A. Kelly

Frequent Co-Authors

Edward K. Wakeland
Edward K. Wakeland The University of Texas Southwestern Medical Center
Chandra Mohan
Chandra Mohan University of Houston
John B. Harley
John B. Harley United States Department of Veterans Affairs
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Nancy J. Olsen
Nancy J. Olsen Penn State Milton S. Hershey Medical Center
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Swapan K. Nath
Swapan K. Nath Oklahoma Medical Research Foundation
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada

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