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Adayapalam T. Natarajan

Adayapalam T. Natarajan

D-Index & Metrics

Molecular Biology

D-Index
88
Citations
24831
World Ranking
787
National Ranking
22

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His main research concerns Molecular biology, Genetics, DNA repair, DNA and Micronucleus test. His Molecular biology research is multidisciplinary, relying on both Chinese hamster ovary cell, Chromosomal translocation, Chromosome, Sister chromatids and Chinese hamster. His Genetics study incorporates themes from Toxicity and Genotoxicity.

His work focuses on many connections between DNA repair and other disciplines, such as DNA damage, that overlap with his field of interest in Genotype. Within one scientific family, he focuses on topics pertaining to Cytotoxic T cell under DNA, and may sometimes address concerns connected to Point mutation and Nitrosourea. His Micronucleus test study combines topics from a wide range of disciplines, such as Sister chromatid exchange, Immunology and Carcinogen.

His most cited work include:

  • Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells (722 citations)
  • IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans (655 citations)
  • Considerations for population monitoring using cytogenetic techniques (503 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Molecular biology, Genetics, DNA, DNA repair and Chromosome. He has included themes like Chinese hamster ovary cell, Chromosomal translocation, Sister chromatids, Fluorescence in situ hybridization and Chinese hamster in his Molecular biology study. The Genetics study combines topics in areas such as Cell biology and Micronucleus test.

His Micronucleus test research is multidisciplinary, incorporating perspectives in In vitro, Immunology and Carcinogen. His biological study spans a wide range of topics, including Mutagenesis and Nucleoid. He has researched Chromosome in several fields, including Telomere and Mitosis.

He most often published in these fields:

  • Molecular biology (60.24%)
  • Genetics (31.33%)
  • DNA (25.30%)

What were the highlights of his more recent work (between 1998-2016)?

  • Molecular biology (60.24%)
  • Genetics (31.33%)
  • Chromosome (19.88%)

In recent papers he was focusing on the following fields of study:

Adayapalam T. Natarajan mostly deals with Molecular biology, Genetics, Chromosome, DNA and DNA repair. Adayapalam T. Natarajan combines subjects such as Base excision repair, DNA damage, Homologous recombination, Sister chromatids and Fluorescence in situ hybridization with his study of Molecular biology. His Genetics research integrates issues from Evolutionary biology and Urine.

The concepts of his Chromosome study are interwoven with issues in Hamster, Chromosomal translocation, Lymphocyte, Telomere and Chinese hamster. His work in DNA addresses subjects such as Human genome, which are connected to disciplines such as Histone and Restriction enzyme. His research integrates issues of Chromatid and Cell biology in his study of DNA repair.

Between 1998 and 2016, his most popular works were:

  • Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells (722 citations)
  • IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans (655 citations)
  • Genotoxic effects of occupational exposure to lead and cadmium. (182 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

His primary scientific interests are in Genetics, Molecular biology, DNA, DNA damage and Sister chromatid exchange. His study in Genetics is interdisciplinary in nature, drawing from both Urine, Physiology and Cell biology. His Molecular biology research includes themes of Telomere, Centromere, Mutant and Chromatid.

As a part of the same scientific family, Adayapalam T. Natarajan mostly works in the field of DNA, focusing on Chromosome and, on occasion, Hybridization probe. His DNA damage research is multidisciplinary, incorporating elements of Andrology, Epoxide hydrolase, Micronucleus and DNA fragmentation. The various areas that Adayapalam T. Natarajan examines in his Sister chromatid exchange study include Carcinogen, Buccal swab, Micronucleus test, Genotoxicity and Comet assay.

Best Publications

  • Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

    M. Fenech;M. Kirsch-Volders;A. T. Natarajan;J. Surralles

  • IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans

    Richard J Albertini;Diana Anderson;George R Douglas;Lars Hagmar

  • Considerations for population monitoring using cytogenetic techniques

    A.V. Carrano;A.T. Natarajan

  • The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

    J. Venema;L. H. F. Mullenders;A. T. Natarajan;A. A. Van Zeeland

  • Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens.

    Siegfried Knasmüller;Wolfram Parzefall;Ratna Sanyal;Sonja Ecker

  • Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.

    J. Venema;A. Van Hoffen;V. Karcagi;A. T. Natarajan

  • Molecular mechanisms involved in the production of chromosomal aberrations. III: Restriction endonucleases

    A. T. Natarajan;G. Obe;G. Obe

  • A proposed system for scoring structural aberrations detected by chromosome painting.

    J. D. Tucker;W. F. Morgan;A. A. Awa;M. Bauchinger

  • Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells.

    van Hoffen A;Natarajan At;Mayne Lv;van Zeeland Aa

  • Molecular mechanisms involved in the production of cromosomal aberrations II. Utilization of neurospora endonuclease for the study of aberration production by X-rays in G1 and G2 stages of the cell cycle

    A.T. Natarajan;Günter Obe;A.A. van Zeeland;F. Palitti

  • The relation between reaction kinetics and mutagenic action of mono-functional alkylating agents in higher eukaryotic systems. I. Recessive lethal mutations and translocations in Drosophila.

    E. Vogel;A.T. Natarajan

  • A unique metabolism of inorganic arsenic in native Andean women

    Marie Vahter;Gabriela Concha;Barbro Nermell;Robert Nilsson

  • The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA

    Jaap Venema;Anneke van Hoffen;A.T. Natarajan;Albert A. van Zeeland

  • Genotoxic effects of occupational exposure to lead and cadmium.

    J Palus;K Rydzynski;E Dziubaltowska;K Wyszynska

  • Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens

    A.T. Natarajan;F. Darroudi

  • Chromosomal aberrations in human lymphocytes induced in vitro by very low doses of X-rays.

    D. C. Lloyd;A. A. Edwards;A. Leonard;G. L. Deknudt

  • Interaction of arsenic(III) with nucleotide excision repair in UV-irradiated human fibroblasts.

    A. Hartwig;U. D. Gröblinghoff;D. Beyersmann;A. T. Natarajan

  • Cytogenetic effects of mutagens/carcinogens after activation in a microsomal system in vitro I. Induction of chromosome aberrations and sister chromatid exchanges by diethylnitrosamine (DEN) and dimethylnitrosamine (DMN) in CHO cells in the presence of rat-liver microsomes.

    A.T. Natarajan;A.D. Tates;P.P.W. van Buul;M. Meijers

  • Use Of Metabolically Competent Human Hepatoma Cells of The Detection Of Mutagens And Antimutagens

    Siegfried Knasmuller;Wolfram Parzefall;Ratna Sanyal;Sonja Ecker

  • Deficient repair ofthetranscribed strand ofactive genes inCockayne's syndrome cells

    A. T. Natarajan;LynneV . Mayne;Albert A. vanZeeland

Frequent Co-Authors

Firouz Darroudi
Firouz Darroudi Leiden University Medical Center
Leon H.F. Mullenders
Leon H.F. Mullenders Leiden University
Günter Obe
Günter Obe University of Duisburg-Essen
Jordi Surrallés
Jordi Surrallés Autonomous University of Barcelona
Paul H.M. Lohman
Paul H.M. Lohman Leiden University Medical Center
Harry Vrieling
Harry Vrieling Leiden University Medical Center
M. Prakash Hande
M. Prakash Hande National University of Singapore
Nicolaas G. J. Jaspers
Nicolaas G. J. Jaspers Erasmus University Rotterdam
Micheline Kirsch-Volders
Micheline Kirsch-Volders Vrije Universiteit Brussel
Alan R. Lehmann
Alan R. Lehmann University of Sussex

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