World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
51
Citations
10515
World Ranking
2499
National Ranking
60

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Mutation

DNA, Molecular biology, DNA repair, Genetics and Saccharomyces cerevisiae are his primary areas of study. His DNA research is included under the broader classification of Biochemistry. His Molecular biology research incorporates elements of Nijmegen breakage syndrome, Pyrimidine dimer, Point mutation, Wild type and Chromosome.

As a member of one scientific family, Paul H.M. Lohman mostly works in the field of DNA repair, focusing on DNA damage and, on occasion, Cell culture. His research in Genetics tackles topics such as Cell biology which are related to areas like Double Strand Break Repair, Cell growth, Yeast and Metabolism. Paul H.M. Lohman has researched Saccharomyces cerevisiae in several fields, including Mutant and Methyl methanesulfonate.

His most cited work include:

  • Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation (834 citations)
  • Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation. (280 citations)
  • cis-Diamminedichloroplatinum(II)-induced DNA Adducts in Peripheral Leukocytes from Seven Cancer Patients: Quantitative Immunochemical Detection of the Adduct Induction and Removal after a Single Dose of cis-Diamminedichloroplatinum(II) (243 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Molecular biology, DNA, DNA repair, Genetics and Mutant. Paul H.M. Lohman combines subjects such as Pyrimidine dimer, Nucleotide excision repair, DNA damage and Mutation, Gene with his study of Molecular biology. DNA is a subfield of Biochemistry that Paul H.M. Lohman investigates.

His DNA repair study combines topics from a wide range of disciplines, such as Cell culture, Nucleic acid sequence, Base pair, Schizosaccharomyces and Alkyltransferase. His biological study spans a wide range of topics, including Exon, Chinese hamster ovary cell, Loss of heterozygosity and Chinese hamster. His Nucleotide research integrates issues from Stereochemistry and Fast protein liquid chromatography.

He most often published in these fields:

  • Molecular biology (61.49%)
  • DNA (45.95%)
  • DNA repair (28.38%)

What were the highlights of his more recent work (between 1996-2005)?

  • Molecular biology (61.49%)
  • Mutant (20.27%)
  • Genetics (27.70%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Molecular biology, Mutant, Genetics, Mutation and Gene. His Molecular biology research incorporates themes from Homologous recombination, Mitotic crossover, Chromosome, Loss of heterozygosity and DNA repair. His research in DNA repair intersects with topics in Potency, Schizosaccharomyces and DNA damage.

The Mutant study combines topics in areas such as DNA-PKcs and Chinese hamster ovary cell. His Mutation research is under the purview of Biochemistry. Paul H.M. Lohman studies Nucleic acid sequence, a branch of DNA.

Between 1996 and 2005, his most popular works were:

  • Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation. (280 citations)
  • Genomic integrity and the repair of double-strand DNA breaks. (230 citations)
  • Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine (201 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

The scientist’s investigation covers issues in Molecular biology, Homologous recombination, Genetics, DNA damage and DNA repair. His work carried out in the field of Molecular biology brings together such families of science as Mutation, Gene and Nibrin, Chromosome instability. His work in Genome, Mitotic crossover and Mutant is related to Genetics.

His research integrates issues of Genetically modified mouse, DNA, Point mutation and Somatic cell in his study of Genome. A large part of his DNA studies is devoted to Nijmegen breakage syndrome. His research investigates the connection between DNA repair and topics such as Saccharomyces cerevisiae that intersect with problems in Cell cycle and Chromosome breakage.

Best Publications

  • Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.

    A. R. Lehmann;S. Kirk-Bell;C. F. Arlett;M. C. Paterson

  • Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo

    J. A. Gossen;W. J.F. De Leeuw;C. H.T. Tan;E. C. Zwarthoff

  • Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation.

    Tonnie Rijkers;Jody Van Den Ouweland;Bruno Morolli;Anton G. Rolink

  • cis-Diamminedichloroplatinum(II)-induced DNA Adducts in Peripheral Leukocytes from Seven Cancer Patients: Quantitative Immunochemical Detection of the Adduct Induction and Removal after a Single Dose of cis-Diamminedichloroplatinum(II)

    Fichtinger-Schepman Am;van Oosterom At;Lohman Ph;Berends F

  • Genomic integrity and the repair of double-strand DNA breaks.

    Albert Pastink;Jan C.J. Eeken;Paul H.M. Lohman

  • Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine

    Martijn E. T. Dollé;Wendy K. Snyder;Jan A. Gossen;Paul H. M. Lohman

  • DNA double-strand break repair by homologous recombination.

    Michael van den Bosch;Paul H M Lohman;Albert Pastink

  • Cloning the RAD51 homologue of Schizosaccharomyces pombe

    D. F. R. Muris;K. Vreeken;A. M. Carr;B. C. Broughton

  • DNA strand specificity for UV-induced mutations in mammalian cells.

    H Vrieling;M L Van Rooijen;N A Groen;M Z Zdzienicka

  • Detection and quantification of adducts formed upon interaction of diamminedichloroplatinum (II) with DNA, by anion-exchange chromatography after enzymatic degradation

    Anne Marie J. Fichtinger-Schepman;Paul H.M. Lohman;Jan Reedijk

  • DNA DAMAGE METABOLISM AND AGING

    E. Mullaart;P.H.M. Lohman;F. Berends;J. Vijg

  • Detection of cyclobutane thymine dimers in DNA of human cells with monoclonal antibodies raised against a thymine dimer-containing tetranucleotide.

    Len Roza;Kees J. M. van der Wulp;Sandra J. MacFarlane;Paul H. M.Lohman

  • Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts.

    Maria Kraakman-van der Zwet;Wilhelmina J.I Overkamp;Anna A Friedl;Binie Klein

  • Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination

    Daan F.R. Muris;Olga Bezzubova;Jean-Marie Buerstedde;Kees Vreeken

  • Formation and repair of DNA interstrand cross-links in relation to cytotoxicity and unscheduled DNA synthesis induced in control and mutant human cells treated with cis-diamminedichloroplatinum(II).

    Plooy Ac;van Dijk M;Berends F;Lohman Ph

  • Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity

    Daan F R Muris;Kees Vreeken;Antony M Carr;Johanne M Murray

  • The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage.

    Petra P. H. Van Sloun;Jacob G. Jansen;Geert Weeda;Leon H. F. Mullenders

  • The quantitative detection of various Pt-DNA-adducts in Chinese hamster ovary cells treated with cisplatin: application of immunochemical techniques

    Adrie C.M. Plooy;Anne Marie J. Fichtinger-Schepman;Henk H. Schutte;Margriet van Dijk

  • Use of computerized data listings and activity profiles of genetic and related effects in the review of 195 compounds.

    M. D. Waters;H. F. Stack;A. L. Brady;P. H. M. Lohman

  • Homologous recombination in the fission yeast Schizosaccharomyces pombe: different requirements for the rhp51+, rhp54+ and rad22+ genes.

    D. F. R. Muris;Kees Vreeken;Henning Schmidt;Kai Ostermann

Frequent Co-Authors

Harry Vrieling
Harry Vrieling Leiden University Medical Center
Leon H.F. Mullenders
Leon H.F. Mullenders Leiden University
Jan Vijg
Jan Vijg Albert Einstein College of Medicine
Adayapalam T. Natarajan
Adayapalam T. Natarajan Leiden University
Nicolaas G. J. Jaspers
Nicolaas G. J. Jaspers Erasmus University Rotterdam
Jan Reedijk
Jan Reedijk Leiden University
Mitsuo Oshimura
Mitsuo Oshimura Tottori University
Stephen P. Jackson
Stephen P. Jackson University of Cambridge
Firouz Darroudi
Firouz Darroudi Leiden University Medical Center
Jan H.J. Hoeijmakers
Jan H.J. Hoeijmakers Erasmus University Rotterdam

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Molecular Biology opens doors to a wide variety of interdisciplinary career paths. Many students explore fields that blend biology with human services, psychology, or counseling, as these areas often intersect in healthcare, research, and academic settings.

For those interested in understanding behavior alongside biological processes, child psychology masters programs offer in-depth knowledge in developmental psychology. If your career goals include providing mental health support, consider some of the cheapest masters in counseling online—an efficient way to gain credentials in counseling, often required in clinical settings.

Those eyeing a direct clinical route can look into the best online clinical psychology programs, which prepare graduates for roles in research or therapy, often at the intersection of biology and psychology. Additionally, earning a degree from online human services degree programs can accelerate entry into supportive roles within hospitals, research labs, or community organizations.

These flexible, accredited options make it easier to combine your passion for biology with careers in health, counseling, and public service.

Best Scientists Citing Paul H.M. Lohman