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Genetics

D-Index
91
Citations
29994
World Ranking
1038
National Ranking
506

Medicine

D-Index
91
Citations
29917
World Ranking
11771
National Ranking
6037

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jan Vijg is affiliated with the Albert Einstein College of Medicine in the United States and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research predominantly focuses on Molecular Biology, Genetics, Cancer Research, Aging, and Physiology.

The scientist's work covers a range of topics including Cancer Genomics and Diagnostics, Genetics, Aging, and Longevity in Model Organisms, Single-cell and spatial transcriptomics, CRISPR and Genetic Engineering, Epigenetics and DNA Methylation, DNA Repair Mechanisms, and Genomics and Rare Diseases.

Jan Vijg has contributed extensively to research publications, with frequent appearances in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Aging
  • Nature
  • Science Advances
  • Frontiers in Aging

Their recent notable papers include:

  • The central role of DNA damage in the ageing process, 2021, Nature
  • Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging, 2020, Cell
  • Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking, 2022, Nature Genetics
  • Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver, 2020, Science Advances
  • From DNA damage to mutations: All roads lead to aging, 2021, Ageing Research Reviews

Jan Vijg has collaborated frequently with several co-authors, including:

  • Shixiang Sun
  • Alexander Y. Maslov
  • Xiao Dong
  • Moonsook Lee
  • Vera Gorbunova

The scientist was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2014.

Best Publications

  • An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

    Marco Demaria;Naoko Ohtani;Sameh A Youssef;Francis Rodier

  • Aging and Genome Maintenance: Lessons from the Mouse?

    Paul Hasty;Judith Campisi;Judith Campisi;Jan Hoeijmakers;Harry van Steeg

  • A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

    Laura J. Niedernhofer;George A. Garinis;Anja Raams;Astrid S. Lalai

  • Increased cell-to-cell variation in gene expression in ageing mouse heart

    Rumana Bahar;Claudia H. Hartmann;Karl A. Rodriguez;Ashley D. Denny

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • The central role of DNA damage in the ageing process

    Björn Schumacher;Joris Pothof;Jan Vijg;Jan Vijg;Jan H. J. Hoeijmakers

  • Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo

    J. A. Gossen;W. J.F. De Leeuw;C. H.T. Tan;E. C. Zwarthoff

  • Puzzles, promises and a cure for ageing.

    Jan Vijg;Judith Campisi;Judith Campisi

  • Evidence for a limit to human lifespan

    Xiao Dong;Brandon Milholland;Jan Vijg

  • DNA damage and ageing: new-age ideas for an age-old problem

    George A. Garinis;Gijsbertus T.J. van der Horst;Jan Vijg;Jan H.J. Hoeijmakers

  • Epigenetic factors in aging and longevity.

    Silvia Gravina;Jan Vijg

  • The overexpression of major antioxidant enzymes does not extend the lifespan of mice

    Viviana I. Pérez;Holly Van Remmen;Alex Bokov;Charles J. Epstein

  • Genome instability and aging.

    Jan Vijg;Yousin Suh

  • Deep biomarkers of human aging: Application of deep neural networks to biomarker development

    Evgeny Putin;Polina Mamoshina;Alexander Aliper;Mikhail Korzinkin

  • Rapid accumulation of genome rearrangements in liver but not in brain of old mice

    Martijn E.T. Dollé;Heidi Giese;Craig L. Hopkins;Hans Jörg Martus

  • Somatic mutations and aging: a re-evaluation

    Jan Vijg

  • Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

    W. P. Vermeij;M. E T Dollé;E. Reiling;D. Jaarsma

  • Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine

    Martijn E. T. Dollé;Wendy K. Snyder;Jan A. Gossen;Paul H. M. Lohman

  • Mechanisms of cancer resistance in long-lived mammals.

    Andrei Seluanov;Vadim N. Gladyshev;Jan Vijg;Vera Gorbunova

  • Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture.

    Rita A. Busuttil;Miguel Rubio;Martijn E. T. Dollé;Judith Campisi;Judith Campisi

Frequent Co-Authors

Yousin Suh
Yousin Suh Columbia University
Judith Campisi
Judith Campisi Buck Institute for Research on Aging
Jan H.J. Hoeijmakers
Jan H.J. Hoeijmakers Erasmus University Rotterdam
Vera Gorbunova
Vera Gorbunova University of Rochester
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital
Charis Eng
Charis Eng Cleveland Clinic Lerner College of Medicine
Paul Hasty
Paul Hasty The University of Texas Health Science Center at San Antonio
Harry van Steeg
Harry van Steeg Centre for Health Protection
Andrei Seluanov
Andrei Seluanov University of Rochester
Arlan Richardson
Arlan Richardson University of Oklahoma Health Sciences Center

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