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Biology and Biochemistry

D-Index
54
Citations
10390
World Ranking
15644
National Ranking
6525

Overview

Yousin Suh is affiliated with Columbia University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on subfields such as Molecular Biology, Aging, Genetics, Physiology, and Cancer Research.

The main topics Yousin Suh has worked on include:

  • Genetics, Aging, and Longevity in Model Organisms
  • CRISPR and Genetic Engineering
  • Genetic Associations and Epidemiology
  • MicroRNA in disease regulation
  • Reproductive Biology and Fertility
  • Telomeres, Telomerase, and Senescence
  • Single-cell and spatial transcriptomics

Among Suh's recent publications are:

  • "SenNet recommendations for detecting senescent cells in different tissues," 2024, Nature Reviews Molecular Cell Biology
  • "Direct diagnostic testing of SARS-CoV-2 without the need for prior RNA extraction," 2021, Scientific Reports
  • "Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging," 2021, Aging Cell
  • "Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice," 2022, Aging Cell
  • "Genetics of extreme human longevity to guide drug discovery for healthy ageing," 2020, Nature Metabolism

Their frequent collaborators feature a core group of researchers including Nir Barzilai, Jan Vijg, Adam D. Hudgins, Yizhou Zhu, and Vera Gorbunova.

Yousin Suh's publications appear regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Aging Cell, Nature Aging, and Scientific Reports.

Best Publications

  • Functionally significant insulin-like growth factor I receptor mutations in centenarians

    Yousin Suh;Gil Atzmon;Mi Ook Cho;David Hwang

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • Genome instability and aging.

    Jan Vijg;Yousin Suh

  • Differences between germline and somatic mutation rates in humans and mice.

    Brandon Milholland;Xiao Dong;Lei Zhang;Xiaoxiao Hao

  • Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians

    Gil Atzmon;Miook Cho;Richard M. Cawthon;Temuri Budagov

  • Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation.

    Jaime L. Schneider;Yousin Suh;Ana Maria Cuervo

  • A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging.

    Mark A. McCormick;Joe R. Delaney;Mitsuhiro Tsuchiya;Scott Tsuchiyama

  • SNP discovery in associating genetic variation with human disease phenotypes.

    Yousin Suh;Jan Vijg;Jan Vijg

  • Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms

    Björn Schumacher;Ingrid van der Pluijm;Michael J. Moorhouse;Theodore Kosteas

  • Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: Implication to age-associated bone diseases and defects

    Mi Jung Kim;Chan Wha Kim;Yu Suk Choi;Min Hwan Kim

  • Resveratrol Rescues SIRT1-Dependent Adult Stem Cell Decline and Alleviates Progeroid Features in Laminopathy-Based Progeria

    Baohua Liu;Baohua Liu;Baohua Liu;Shrestha Ghosh;Xi Yang;Huiling Zheng;Huiling Zheng

  • Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

    Caroline Park;Yousin Suh;Ana Maria Cuervo

  • Targeted inactivation of MLL3 histone H3–Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

    Jeongkyung Lee;Pradip K. Saha;Qi-Heng Yang;Seunghee Lee

  • Genetics of longevity and aging.

    Jan Vijg;Yousin Suh

  • MRP2 haplotypes confer differential susceptibility to toxic liver injury

    Ji Ha Choi;Byung Min Ahn;Jihyun Yi;Ji Hyun Lee

  • LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control

    Jianxun Wang;Jianxun Wang;Francesca Telese;Yuliang Tan;Wenbo Li

  • A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases

    Ji Hyun Lee;Ji Ha Choi;Wan Namkung;John W. Hanrahan

  • In vivo genome editing in animals using AAV-CRISPR system: applications to translational research of human disease

    Cia Hin Lau;Yousin Suh

  • Aging alters the apoptotic response to genotoxic stress

    Yousin Suh;Kang Ae Lee;Woo Ho Kim;Bok Ghee Han

  • MicroRNA in Aging: From Discovery to Biology.

    Hwa Jin Jung;Yousin Suh

Frequent Co-Authors

Jan Vijg
Jan Vijg Albert Einstein College of Medicine
Brian K. Kennedy
Brian K. Kennedy National University of Singapore
Matt Kaeberlein
Matt Kaeberlein University of Washington
Nir Barzilai
Nir Barzilai Albert Einstein College of Medicine
Gil Atzmon
Gil Atzmon Albert Einstein College of Medicine
Laura J. Niedernhofer
Laura J. Niedernhofer University of Minnesota
Jan H.J. Hoeijmakers
Jan H.J. Hoeijmakers Erasmus University Rotterdam
Vera Gorbunova
Vera Gorbunova University of Rochester
David A. Sinclair
David A. Sinclair Harvard University
Paul D. Robbins
Paul D. Robbins University of Minnesota

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