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Genetics
Netherlands
2026
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Molecular Biology
Netherlands
2026

D-Index & Metrics

Genetics

D-Index
143
Citations
79829
World Ranking
171
National Ranking
6

Molecular Biology

D-Index
143
Citations
79829
World Ranking
108
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Genetics in Netherlands Leader Award
  • 2026 - Research.com Molecular Biology in Netherlands Leader Award
  • 2025 - Research.com Genetics in Netherlands Leader Award
  • 2025 - Research.com Molecular Biology in Netherlands Leader Award
  • 2024 - Research.com Genetics in Netherlands Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Netherlands Leader Award
  • 2023 - Research.com Genetics in Netherlands Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Netherlands Leader Award
  • 2000 - Royal Netherlands Academy of Arts and Sciences
  • 1998 - Spinoza Prize, Dutch Research Council
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jan H.J. Hoeijmakers is affiliated with Erasmus University Rotterdam in the Netherlands. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, physiology, aging, genetics, and pediatrics, perinatology, and child health.

The scientist's primary research topics include DNA repair mechanisms, genetics, aging, and longevity in model organisms, RNA research and splicing, mitochondrial function and pathology, diet and metabolism studies, dietary effects on health, and RNA modifications and cancer.

Frequent co-authors collaborating with Jan H.J. Hoeijmakers include Wilbert P. Vermeij, Sander Barnhoorn, Renata M. C. Brandt, Jan Vijg, and Ákos Gyenis.

Publications by Jan H.J. Hoeijmakers have appeared predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature, Aging Cell, Nature Aging, and Nature Genetics.

Notable recent papers include:

  • The central role of DNA damage in the ageing process, 2021, Nature
  • Genome-wide RNA polymerase stalling shapes the transcriptome during aging, 2023, Nature Genetics
  • ARDD 2020: from aging mechanisms to interventions, 2020, Aging
  • Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy, 2021, Human Molecular Genetics
  • Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses, 2024, Nature Aging

Jan H.J. Hoeijmakers has received several recognitions throughout their career, including membership in the Royal Netherlands Academy of Arts and Sciences in 2000, the Spinoza Prize awarded by the Dutch Research Council in 1998, and membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Genome maintenance mechanisms for preventing cancer

    Jan H. J. Hoeijmakers

  • DNA Damage, Aging, and Cancer

    Jan H. J. Hoeijmakers

  • An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

    Marco Demaria;Naoko Ohtani;Sameh A Youssef;Francis Rodier

  • Chromosomal stability and the DNA double-stranded break connection.

    Dik C. van Gent;Jan H. J. Hoeijmakers;Roland Kanaar

  • Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms.

    Gijsbertus T.J. Van Der Horst;Manja Muijtjens;Kumiko Kobayashi;Riya Takano

  • Molecular mechanism of nucleotide excision repair

    W. L. De Laat;N. G. J. Jaspers;J. H. J. Hoeijmakers

  • Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

    Marjolein P. Baar;Renata M.C. Brandt;Diana A. Putavet;Julian D.D. Klein

  • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

    Derrick J Rossi;David Bryder;David Bryder;Jun Seita;Andre Nussenzweig

  • Understanding nucleotide excision repair and its roles in cancer and ageing

    Jurgen A. Marteijn;Hannes Lans;Wim Vermeulen;Jan H. J. Hoeijmakers

  • Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

    Kaoru Sugasawa;Jessica M.Y Ng;Chikahide Masutani;Shigenori Iwai

  • DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor

    Laurent Schaeffer;Richard Roy;Sandrine Humbert;Vincent Moncollin

  • Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo

    Marcel Volker;Martijn J Moné;Parimal Karmakar;Anneke van Hoffen

  • Nucleotide excision repair and human syndromes

    Jan de Boer;Jan H.J. Hoeijmakers

  • ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes.

    Christine Troelstra;Alain van Gool;Jan de Wit;Wim Vermeulen

  • Cellular senescence drives age-dependent hepatic steatosis.

    Mikolaj Ogrodnik;Satomi Miwa;Tamar Tchkonia;Dina Tiniakos;Dina Tiniakos

  • Aging and Genome Maintenance: Lessons from the Mouse?

    Paul Hasty;Judith Campisi;Judith Campisi;Jan Hoeijmakers;Harry van Steeg

  • Molecular mechanisms of DNA double-strand break repair

    Roland Kanaar;Jan H.J Hoeijmakers;Dik C van Gent

  • A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

    Laura J. Niedernhofer;George A. Garinis;Anja Raams;Astrid S. Lalai

  • p53 modulation of TFIIH-associated nucleotide excision repair activity.

    Xin Wei Wang;H. Yeh;L. Schaeffer;Richard Roy

  • Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

    Anneke M. Sijbers;Wouter L. De Laat;Rafael R. Ariza;Maureen Biggerstaff

Frequent Co-Authors

Wim Vermeulen
Wim Vermeulen Erasmus University Rotterdam
Dirk Bootsma
Dirk Bootsma Erasmus University Rotterdam
Gijsbertus T. J. van der Horst
Gijsbertus T. J. van der Horst Erasmus University Rotterdam
Nicolaas G. J. Jaspers
Nicolaas G. J. Jaspers Erasmus University Rotterdam
Roland Kanaar
Roland Kanaar Erasmus University Rotterdam
Harry van Steeg
Harry van Steeg Centre for Health Protection
Laura J. Niedernhofer
Laura J. Niedernhofer University of Minnesota
Jan Vijg
Jan Vijg Albert Einstein College of Medicine
Jan de Boer
Jan de Boer Antoni van Leeuwenhoek Hospital
Kaoru Sugasawa
Kaoru Sugasawa Kobe University

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