What is he best known for?
The fields of study he is best known for:
Jan H.J. Hoeijmakers mainly focuses on DNA repair, Nucleotide excision repair, Molecular biology, Genetics and DNA damage.
His DNA repair research integrates issues from Cancer research and Helicase.
The Cancer research study combines topics in areas such as Senescence and Progeria.
His work deals with themes such as Replication protein A and Xeroderma pigmentosum, which intersect with Nucleotide excision repair.
The various areas that Jan H.J. Hoeijmakers examines in his Molecular biology study include Mutant, General transcription factor, DNA-binding protein, Cell biology and Histone.
His DNA damage study combines topics in areas such as Mutation, Proliferating cell nuclear antigen, Homologous recombination and Ageing.
His most cited work include:
- Genome maintenance mechanisms for preventing cancer (3232 citations)
- DNA Damage, Aging, and Cancer (1361 citations)
- Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. (1093 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include DNA repair, Nucleotide excision repair, Genetics, Molecular biology and DNA damage.
His biological study spans a wide range of topics, including Cancer research and Cell biology.
The concepts of his Cell biology study are interwoven with issues in Chromatin, Cell cycle and Replication protein A.
His Nucleotide excision repair research incorporates elements of Transcription and Helicase.
His study focuses on the intersection of Molecular biology and fields such as Pyrimidine dimer with connections in the field of Photolyase.
His DNA damage research includes elements of Internal medicine, Senescence and Endocrinology.
He most often published in these fields:
- DNA repair (55.45%)
- Nucleotide excision repair (43.83%)
- Genetics (36.80%)
What were the highlights of his more recent work (between 2013-2021)?
- DNA damage (31.48%)
- DNA repair (55.45%)
- Internal medicine (11.14%)
In recent papers he was focusing on the following fields of study:
Jan H.J. Hoeijmakers mainly investigates DNA damage, DNA repair, Internal medicine, Genetics and Cell biology.
His DNA damage research is included under the broader classification of DNA.
His DNA repair research is multidisciplinary, relying on both Molecular biology, Cancer research and Genome instability.
His Internal medicine study also includes fields such as
- Endocrinology which is related to area like Senescence, Ageing and Transcriptome,
- Oncology which is related to area like Cancer, Cancer treatment and Chemotherapy.
His Cell biology study integrates concerns from other disciplines, such as Cell, Transcription and Deficient mouse.
His Nucleotide excision repair study combines topics from a wide range of disciplines, such as Point mutation and Somatic cell.
Between 2013 and 2021, his most popular works were:
- An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA (732 citations)
- Understanding nucleotide excision repair and its roles in cancer and ageing (575 citations)
- Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging (527 citations)
In his most recent research, the most cited papers focused on:
Jan H.J. Hoeijmakers spends much of his time researching DNA damage, DNA repair, Cell biology, Genetics and Senescence.
Jan H.J. Hoeijmakers works in the field of DNA damage, namely Nucleotide excision repair.
His research integrates issues of Cytotoxic T cell, RNA polymerase II and DNA replication in his study of Nucleotide excision repair.
His research on DNA repair also deals with topics like
- Genome instability which is related to area like Gene,
- Molecular biology and related Cancer.
His Genetics study frequently links to adjacent areas such as Human studies.
His work deals with themes such as Genotoxic Stress, Endocrinology and Cancer research, which intersect with Senescence.
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