World's Best Scientists 2026 revealed!
Alexander F. Yakunin

Alexander F. Yakunin

D-Index & Metrics

Chemistry

D-Index
55
Citations
8438
World Ranking
12391
National Ranking
702

Biology and Biochemistry

D-Index
59
Citations
18047
World Ranking
12310
National Ranking
947

Overview

Alexander F. Yakunin is affiliated with Bangor University in the United Kingdom and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology, Biotechnology, Biomedical Engineering, Genetics, and Plant Science.

The scientist's recent publications cover a range of topics within biochemical research and microbial enzymology. Notable papers include:

  • CRISPR-induced DNA reorganization for multiplexed nucleic acid detection, 2023, Nature Communications
  • Lignin-oxidizing activity of bacterial laccases characterized using soluble substrates and polymeric lignin, 2020, Journal of Biotechnology
  • Defluorination Capability of l-2-Haloacid Dehalogenases in the HAD-Like Hydrolase Superfamily Correlates with Active Site Compactness, 2021, ChemBioChem
  • Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases, 2023, FEBS Journal
  • Metabolite Damage and Damage Control in a Minimal Genome, 2022, mBio

Frequent coauthors in Yakunin's research include Anna N. Khusnutdinova, Radhakrishnan Mahadevan, Patrick Diep, Alexei Savchenko, and P.J. Stogios.

Research is disseminated in several academic venues with multiple publications found in bioRxiv (Cold Spring Harbor Laboratory), FEBS Journal, ACS Catalysis, ACS Chemical Biology, and Analytical Biochemistry.

The scientist's work addresses various main topics, such as:

  • Microbial Metabolic Engineering and Bioproduction
  • Biochemical and biochemical processes
  • RNA and protein synthesis mechanisms
  • Bacterial Genetics and Biotechnology
  • Trace Elements in Health
  • Viral Infectious Diseases and Gene Expression in Insects
  • Biofuel production and bioconversion

Best Publications

  • Evolution and classification of the CRISPR-Cas systems

    Kira S. Makarova;Daniel H. Haft;Rodolphe Barrangou;Stan J. J. Brouns

  • An updated evolutionary classification of CRISPR–Cas systems

    Kira S. Makarova;Yuri I. Wolf;Omer S. Alkhnbashi;Fabrizio Costa

  • Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.

    Kira S. Makarova;Yuri I. Wolf;Jaime Iranzo;Sergey A. Shmakov

  • Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.

    Ekaterina Kuznetsova;Michael Proudfoot;Claudio F. Gonzalez;Greg Brown

  • A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

    Mohan Babu;Natalia Beloglazova;Robert Flick;Chris Graham

  • Heavy Metal Removal by Bioaccumulation Using Genetically Engineered Microorganisms.

    Patrick Diep;Radhakrishnan Mahadevan;Alexander F. Yakunin

  • In situ proteolysis for protein crystallization and structure determination

    Aiping Dong;Xiaohui Xu;Aled M. Edwards;Changsoo Chang

  • A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.

    Natalia Beloglazova;Natalia Beloglazova;Greg Brown;Greg Brown;Matthew D. Zimmerman;Matthew D. Zimmerman;Michael Proudfoot;Michael Proudfoot

  • Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

    Natalia Beloglazova;Robert Flick;Anatoli Tchigvintsev;Greg Brown

  • Enzyme genomics: Application of general enzymatic screens to discover new enzymes⋆

    Ekaterina Kuznetsova;Ekaterina Kuznetsova;Michael Proudfoot;Stephen A. Sanders;Jeffrey Reinking

  • Biochemical and structural insights into enzymatic depolymerization of polylactic acid and other polyesters by microbial carboxylesterases

    Mahbod Hajighasemi;Boguslaw P. Nocek;Anatoli Tchigvintsev;Greg Brown

  • Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference

    Natalia Beloglazova;Pierre Petit;Robert Flick;Greg Brown

  • SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

    Constanze Schneider;Thomas Oellerich;Hanna-Mari Baldauf;Hanna-Mari Baldauf;Sarah-Marie Schwarz

  • Molecular Basis of Formaldehyde Detoxification CHARACTERIZATION OF TWO S-FORMYLGLUTATHIONE HYDROLASES FROM ESCHERICHIA COLI, FrmB AND YeiG

    Claudio F. Gonzalez;Michael Proudfoot;Greg Brown;Yurij Korniyenko

  • Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria

    Boguslaw Nocek;Samvel Kochinyan;Michael Proudfoot;Greg Brown

  • Riboneogenesis in yeast.

    Michelle F. Clasquin;Eugene Melamud;Alexander Singer;Jessica R. Gooding

  • Aspartate Dehydrogenase, a Novel Enzyme Identified from Structural and Functional Studies of TM1643

    Zhiru Yang;Alexei Savchenko;Alexander Yakunin;Rongguang Zhang

  • Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases

    Anatoli Tchigvintsev;Xiaohui Xu;Alexander Singer;Changsoo Chang

  • Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica

    Michael Kube;Tatyana N. Chernikova;Yamal Al-Ramahi;Ana Beloqui

  • Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli.

    Ruslan Sanishvili;Alexander F. Yakunin;Roman A. Laskowski;Tatiana Skarina

  • The COMBREX Project: Design, Methodology, and Initial Results

    Brian P. Anton;Yi-Chien Chang;Peter Brown;Han-Pil Choi

Frequent Co-Authors

Alexei Savchenko
Alexei Savchenko University of Calgary
Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Radhakrishnan Mahadevan
Radhakrishnan Mahadevan University of Toronto
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Michail M. Yakimov
Michail M. Yakimov National Research Council (CNR)
Peter N. Golyshin
Peter N. Golyshin Bangor University
Manuel Ferrer
Manuel Ferrer Spanish National Research Council
Elizabeth A. Edwards
Elizabeth A. Edwards University of Toronto
Eugene V. Koonin
Eugene V. Koonin National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Chemistry, exploring related online degrees can open diverse career pathways. Understanding the cost and commitment involved is crucial, as programs vary in price depending on the level of study and institution. For example, if you’re curious about program expenses, this guide on how much is criminal justice degree offers insights that can be useful when comparing tuition fees across disciplines.

Many students start with foundation programs like an online associates in criminal justice, which can be parallel to foundational science degrees before transferring to advanced chemistry courses. This pathway allows flexibility and skill-building before specializing further.

Beyond the lab, chemical knowledge pairs well with fields like legal compliance or pharmaceutical industries. The article about types of paralegals highlights how legal expertise complements scientific roles, especially in patent law and regulatory affairs.

Alternatively, combining science with business can lead to roles such as pharmaceutical sales, a sector with promising growth and earning potential. Learn more about how much do pharmaceutical sales reps make and the career steps involved to see if this path aligns with your goals.

Best Scientists Citing Alexander F. Yakunin

Trending Scientists

Recently Published Articles