D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 10,408 252 World Ranking 8490 National Ranking 291

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

His primary areas of study are Biochemistry, Genetics, Protein structure, Enzyme and Structural genomics. His is involved in several facets of Biochemistry study, as is seen by his studies on Escherichia coli, Nuclease, Phosphatase, Active site and Thermotoga maritima. When carried out as part of a general Genetics research project, his work on CRISPR, Genome and Genome size is frequently linked to work in CRISPR Loci and Context, therefore connecting diverse disciplines of study.

His study on Protein structure also encompasses disciplines like

  • Functional genomics together with Proteolytic enzymes and Protein Structure Initiative,
  • DNA ligase, Ubiquitin-Protein Ligases, Effector, Ubiquitin ligase and Plasma protein binding most often made with reference to Conserved sequence. His work in Enzyme covers topics such as Sequence analysis which are related to areas like RRNA processing, RNA and Protein domain. His research integrates issues of Structural proteomics, Computational biology, Whole genome sequencing and Comparative genomics in his study of Structural genomics.

His most cited work include:

  • Protein production and purification. (655 citations)
  • Structural proteomics of an archaeon. (268 citations)
  • Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family. (231 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Biochemistry, Enzyme, Stereochemistry, Protein structure and Structural genomics. His study in Biochemistry concentrates on Escherichia coli, Active site, Hydrolase, Peptide sequence and Binding site. His research in Enzyme intersects with topics in Aminoglycoside, Gene and Cell biology.

Within one scientific family, Alexei Savchenko focuses on topics pertaining to Crystal structure under Stereochemistry, and may sometimes address concerns connected to Thermotoga maritima. His Protein structure study combines topics from a wide range of disciplines, such as TetR, Dimer, Sequence analysis and Conserved sequence. His Structural genomics research integrates issues from Genetics and Computational biology.

He most often published in these fields:

  • Biochemistry (60.78%)
  • Enzyme (26.50%)
  • Stereochemistry (21.55%)

What were the highlights of his more recent work (between 2016-2021)?

  • Enzyme (26.50%)
  • Biochemistry (60.78%)
  • Cell biology (11.66%)

In recent papers he was focusing on the following fields of study:

Alexei Savchenko mainly focuses on Enzyme, Biochemistry, Cell biology, Effector and Antibiotic resistance. The Enzyme study combines topics in areas such as Tobramycin, Stereochemistry, Carboxylic acid and Adipic acid. His work in Active site, Prenylation, Cofactor, Hydrolase and Esterase are all subfields of Biochemistry research.

In general Cell biology study, his work on Signal transduction often relates to the realm of Immunity, thereby connecting several areas of interest. His Effector research is multidisciplinary, relying on both Ubiquitin, Secretion, Legionella pneumophila, Escherichia coli and Phosphorylation. Alexei Savchenko is researching Antibiotic resistance as part of the investigation of Antibiotics and Genetics.

Between 2016 and 2021, his most popular works were:

  • Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes (53 citations)
  • Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes (53 citations)
  • Determinants and Prediction of Esterase Substrate Promiscuity Patterns (39 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Bacteria

Alexei Savchenko mostly deals with Cell biology, Enzyme, Effector, Biochemistry and Antibiotics. His work on Signal transduction as part of general Cell biology research is frequently linked to CD22, bridging the gap between disciplines. His study in Enzyme is interdisciplinary in nature, drawing from both Legionella, Ubiquitin, Protein family and Metagenomics.

Alexei Savchenko has researched Effector in several fields, including Secretion, Legionella pneumophila, NEDD8, Pathogenic bacteria and Gene. His Biochemistry research incorporates elements of Polyester and Stereochemistry. His studies deal with areas such as Methyltransferase, Structure–activity relationship and Enterobacteriaceae as well as Antibiotics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Protein production and purification.

S Gräslund.
Nature Methods (2008)

898 Citations

Structural proteomics of an archaeon.

Dinesh Christendat;Adelinda Yee;Akil Dharamsi;Yuval Kluger.
Nature Structural & Molecular Biology (2000)

416 Citations

A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

Mohan Babu;Natalia Beloglazova;Robert Flick;Chris Graham.
Molecular Microbiology (2011)

317 Citations

Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.

Ekaterina Kuznetsova;Michael Proudfoot;Claudio F. Gonzalez;Greg Brown.
Journal of Biological Chemistry (2006)

304 Citations

In situ proteolysis for protein crystallization and structure determination

Aiping Dong;Xiaohui Xu;Aled M. Edwards;Changsoo Chang.
Nature Methods (2007)

281 Citations

A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.

Natalia Beloglazova;Natalia Beloglazova;Greg Brown;Greg Brown;Matthew D. Zimmerman;Matthew D. Zimmerman;Michael Proudfoot;Michael Proudfoot.
Journal of Biological Chemistry (2008)

247 Citations

Cloning, sequencing, and expression of the gene encoding amylopullulanase from Pyrococcus furiosus and biochemical characterization of the recombinant enzyme.

G Dong;C Vieille;A Savchenko;J G Zeikus.
Applied and Environmental Microbiology (1997)

221 Citations

Enzyme genomics: Application of general enzymatic screens to discover new enzymes⋆

Ekaterina Kuznetsova;Ekaterina Kuznetsova;Michael Proudfoot;Stephen A. Sanders;Jeffrey Reinking.
Fems Microbiology Reviews (2005)

185 Citations

PoxA, YjeK, and Elongation Factor P Coordinately Modulate Virulence and Drug Resistance in Salmonella enterica

William Wiley Navarre;S. Betty Zou;Hervé Roy;Jinglin Lucy Xie.
Molecular Cell (2010)

179 Citations

Thermozymes: biotechnology and structure-function relationships.

J. G. Zeikus;Claire Vieille;Alexei Savchenko.
Extremophiles (1998)

173 Citations

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