His primary areas of study are Biochemistry, Genetics, Protein structure, Enzyme and Structural genomics. His is involved in several facets of Biochemistry study, as is seen by his studies on Escherichia coli, Nuclease, Phosphatase, Active site and Thermotoga maritima. When carried out as part of a general Genetics research project, his work on CRISPR, Genome and Genome size is frequently linked to work in CRISPR Loci and Context, therefore connecting diverse disciplines of study.
His study on Protein structure also encompasses disciplines like
His scientific interests lie mostly in Biochemistry, Enzyme, Stereochemistry, Protein structure and Structural genomics. His study in Biochemistry concentrates on Escherichia coli, Active site, Hydrolase, Peptide sequence and Binding site. His research in Enzyme intersects with topics in Aminoglycoside, Gene and Cell biology.
Within one scientific family, Alexei Savchenko focuses on topics pertaining to Crystal structure under Stereochemistry, and may sometimes address concerns connected to Thermotoga maritima. His Protein structure study combines topics from a wide range of disciplines, such as TetR, Dimer, Sequence analysis and Conserved sequence. His Structural genomics research integrates issues from Genetics and Computational biology.
Alexei Savchenko mainly focuses on Enzyme, Biochemistry, Cell biology, Effector and Antibiotic resistance. The Enzyme study combines topics in areas such as Tobramycin, Stereochemistry, Carboxylic acid and Adipic acid. His work in Active site, Prenylation, Cofactor, Hydrolase and Esterase are all subfields of Biochemistry research.
In general Cell biology study, his work on Signal transduction often relates to the realm of Immunity, thereby connecting several areas of interest. His Effector research is multidisciplinary, relying on both Ubiquitin, Secretion, Legionella pneumophila, Escherichia coli and Phosphorylation. Alexei Savchenko is researching Antibiotic resistance as part of the investigation of Antibiotics and Genetics.
Alexei Savchenko mostly deals with Cell biology, Enzyme, Effector, Biochemistry and Antibiotics. His work on Signal transduction as part of general Cell biology research is frequently linked to CD22, bridging the gap between disciplines. His study in Enzyme is interdisciplinary in nature, drawing from both Legionella, Ubiquitin, Protein family and Metagenomics.
Alexei Savchenko has researched Effector in several fields, including Secretion, Legionella pneumophila, NEDD8, Pathogenic bacteria and Gene. His Biochemistry research incorporates elements of Polyester and Stereochemistry. His studies deal with areas such as Methyltransferase, Structure–activity relationship and Enterobacteriaceae as well as Antibiotics.
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Protein production and purification.
S Gräslund.
Nature Methods (2008)
Structural proteomics of an archaeon.
Dinesh Christendat;Adelinda Yee;Akil Dharamsi;Yuval Kluger.
Nature Structural & Molecular Biology (2000)
A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair
Mohan Babu;Natalia Beloglazova;Robert Flick;Chris Graham.
Molecular Microbiology (2011)
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.
Ekaterina Kuznetsova;Michael Proudfoot;Claudio F. Gonzalez;Greg Brown.
Journal of Biological Chemistry (2006)
In situ proteolysis for protein crystallization and structure determination
Aiping Dong;Xiaohui Xu;Aled M. Edwards;Changsoo Chang.
Nature Methods (2007)
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.
Natalia Beloglazova;Natalia Beloglazova;Greg Brown;Greg Brown;Matthew D. Zimmerman;Matthew D. Zimmerman;Michael Proudfoot;Michael Proudfoot.
Journal of Biological Chemistry (2008)
Cloning, sequencing, and expression of the gene encoding amylopullulanase from Pyrococcus furiosus and biochemical characterization of the recombinant enzyme.
G Dong;C Vieille;A Savchenko;J G Zeikus.
Applied and Environmental Microbiology (1997)
Enzyme genomics: Application of general enzymatic screens to discover new enzymes⋆
Ekaterina Kuznetsova;Ekaterina Kuznetsova;Michael Proudfoot;Stephen A. Sanders;Jeffrey Reinking.
Fems Microbiology Reviews (2005)
PoxA, YjeK, and Elongation Factor P Coordinately Modulate Virulence and Drug Resistance in Salmonella enterica
William Wiley Navarre;S. Betty Zou;Hervé Roy;Jinglin Lucy Xie.
Molecular Cell (2010)
Thermozymes: biotechnology and structure-function relationships.
J. G. Zeikus;Claire Vieille;Alexei Savchenko.
Extremophiles (1998)
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