World's Best Scientists 2026 revealed!
Alexei Savchenko

Alexei Savchenko

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
14938
World Ranking
6781
National Ranking
239

Overview

Alexei Savchenko is affiliated with the University of Calgary in Canada and has a research focus largely situated within the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their body of work includes significant contributions to subfields such as Molecular Biology, Infectious Diseases, Endocrinology, Genetics, and Molecular Medicine.

The research topics addressed by Savchenko cover a diverse range of biomedical and microbiological areas. Key topics include:

  • Antibiotic Resistance in Bacteria
  • RNA and protein synthesis mechanisms
  • Bacterial Genetics and Biotechnology
  • Vibrio bacteria research studies
  • Legionella and Acanthamoeba research
  • Antifungal resistance and susceptibility
  • SARS-CoV-2 and COVID-19 Research

Savchenko's recent academic publications reflect this thematic breadth with studies published in venues ranging from high-impact journals to specialized scientific periodicals. Selected recent papers include:

  • "Molecular mechanisms of vancomycin resistance," 2020, Protein Science
  • "Envelope stress responses defend against type six secretion system attacks independently of immunity proteins," 2020, Nature Microbiology
  • "A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase," 2021, Nature Communications
  • "Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics," 2023, Nature Communications
  • "Structural characterization of nonstructural protein 1 from SARS-CoV-2," 2020, iScience

Frequent collaborators in Savchenko's work include:

  • P.J. Stogios
  • Cameron Semper
  • T. Skarina
  • Dominika Borek
  • Alexander F. Yakunin

The scientist's publications are commonly found in journals and platforms such as bioRxiv (Cold Spring Harbor Laboratory), Protein Science, Nature Communications, mBio, and the FEBS Journal. This distribution indicates a consistent engagement with both preliminary and peer-reviewed publications within molecular biosciences and microbiology.

Best Publications

  • Protein production and purification.

    S Gräslund

  • Epicardial FSTL1 reconstitution regenerates the adult mammalian heart

    Ke Wei;Ke Wei;Vahid Serpooshan;Cecilia Hurtado;Cecilia Hurtado;Marta Diez-Cuñado;Marta Diez-Cuñado;Marta Diez-Cuñado

  • Structural proteomics of an archaeon.

    Dinesh Christendat;Adelinda Yee;Akil Dharamsi;Yuval Kluger

  • Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.

    Ekaterina Kuznetsova;Michael Proudfoot;Claudio F. Gonzalez;Greg Brown

  • A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

    Mohan Babu;Natalia Beloglazova;Robert Flick;Chris Graham

  • In situ proteolysis for protein crystallization and structure determination

    Aiping Dong;Xiaohui Xu;Aled M. Edwards;Changsoo Chang

  • Structure-function analysis identifies highly sensitive strigolactone receptors in Striga.

    Shigeo Toh;Duncan Holbrook-Smith;Peter J. Stogios;Olena Onopriyenko

  • A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.

    Natalia Beloglazova;Natalia Beloglazova;Greg Brown;Greg Brown;Matthew D. Zimmerman;Matthew D. Zimmerman;Michael Proudfoot;Michael Proudfoot

  • Molecular mechanisms of vancomycin resistance.

    Peter J Stogios;Alexei Savchenko;Alexei Savchenko

  • Enzyme genomics: Application of general enzymatic screens to discover new enzymes⋆

    Ekaterina Kuznetsova;Ekaterina Kuznetsova;Michael Proudfoot;Stephen A. Sanders;Jeffrey Reinking

  • PoxA, YjeK, and Elongation Factor P Coordinately Modulate Virulence and Drug Resistance in Salmonella enterica

    William Wiley Navarre;S. Betty Zou;Hervé Roy;Jinglin Lucy Xie

  • Thermozymes: biotechnology and structure-function relationships.

    J. G. Zeikus;Claire Vieille;Alexei Savchenko

  • Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference

    Natalia Beloglazova;Pierre Petit;Robert Flick;Greg Brown

  • Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.

    Alexander U Singer;John R Rohde;Robert Lam;Tatiana Skarina

  • Molecular Basis of Formaldehyde Detoxification CHARACTERIZATION OF TWO S-FORMYLGLUTATHIONE HYDROLASES FROM ESCHERICHIA COLI, FrmB AND YeiG

    Claudio F. Gonzalez;Michael Proudfoot;Greg Brown;Yurij Korniyenko

  • NMR and X-ray Crystallography, Complementary Tools in Structural Proteomics of Small Proteins

    Adelinda A Yee;Alexei Savchenko;Alexandr Ignachenko;Jonathan Lukin

  • A comprehensive analysis of structural and sequence conservation in the TetR family transcriptional regulators.

    Zhou Yu;Sean E. Reichheld;Alexei Savchenko;John Parkinson

  • The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor

    Sergey Korolev;Yoshihiko Ikeguchi;Tatiana Skarina;Steven Beasley

  • Aspartate Dehydrogenase, a Novel Enzyme Identified from Structural and Functional Studies of TM1643

    Zhiru Yang;Alexei Savchenko;Alexander Yakunin;Rongguang Zhang

  • In situ proteolysis for protein crystallization and structure determination

    A. Dong;X. Xu;A. Bochkarev;A. Savchenko

Frequent Co-Authors

Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Alexander F. Yakunin
Alexander F. Yakunin Bangor University
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Wladek Minor
Wladek Minor University of Virginia
Peter N. Golyshin
Peter N. Golyshin Bangor University
Youngchang Kim
Youngchang Kim Argonne National Laboratory
Wayne F. Anderson
Wayne F. Anderson Northwestern University
Gerard D. Wright
Gerard D. Wright McMaster University
Michail M. Yakimov
Michail M. Yakimov National Research Council (CNR)

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