World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
65
Citations
50232
World Ranking
7525
National Ranking
2201

Biology and Biochemistry

D-Index
66
Citations
50558
World Ranking
8424
National Ranking
3794

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Wladek Minor is affiliated with the University of Virginia in the United States and has made significant contributions to the field of Biochemistry, Genetics, and Molecular Biology. Their research primarily focuses on molecular biology, materials chemistry, computational theory and mathematics, infectious diseases, and oncology.

The main topics of their work include:

  • Enzyme Structure and Function
  • Protein Structure and Dynamics
  • Computational Drug Discovery Methods
  • Protein Interaction Studies and Fluorescence Analysis
  • Drug Transport and Resistance Mechanisms
  • SARS-CoV-2 and COVID-19 Research
  • Genetics, Bioinformatics, and Biomedical Research

Wladek Minor has published extensively, with frequent contributions to several scientific journals. Key publication venues include:

  • Acta Crystallographica Section A Foundations and Advances
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • IUCrJ
  • Protein Science
  • FEBS Journal

The scientist's recent papers cover various aspects of structural biology, drug discovery, and enzymology. Notable works include:

  • CMM-An enhanced platform for interactive validation of metal binding sites (2022, Protein Science)
  • Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma (2020, Journal of Medicinal Chemistry)
  • Ligand-centered assessment of SARS-CoV-2 drug target models in the Protein Data Bank (2020, FEBS Journal)
  • The current role and evolution of X-ray crystallography in drug discovery and development (2023, Expert Opinion on Drug Discovery)
  • Regioselectivity of hyoscyamine 6β-hydroxylase-catalysed hydroxylation as revealed by high-resolution structural information and QM/MM calculations (2020, Dalton Transactions)

Frequent collaborators in the scientist's work include:

  • David R. Cooper
  • I.G. Shabalin
  • Dariusz Brzeziński
  • Michał Gucwa
  • Zbigniew Dauter

Wladek Minor's contributions to the scientific community have been recognized by the American Association for the Advancement of Science, which named them a Fellow in 2018.

Best Publications

  • Processing of X-ray diffraction data collected in oscillation mode

    Zbyszek Otwinowski;Wladek Minor

  • HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes.

    Wladek Minor;Marcin Cymborowski;Zbyszek Otwinowski;Maksymilian Chruszcz

  • Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.

    Karolina A. Majorek;Przemyslaw J. Porebski;Arjun Dayal;Matthew D. Zimmerman

  • Multiparametric scaling of diffraction intensities

    Zbyszek Otwinowski;Dominika Borek;Wladyslaw Majewski;Wladek Minor

  • Double chromodomains cooperate to recognize the methylated histone H3 tail

    John F. Flanagan;Li-Zhi Mi;Maksymilian Chruszcz;Marcin Cymborowski

  • Crystal structure of soybean lipoxygenase L-1 at 1.4 Å resolution

    Wladek Minor;Janusz Steczko;Janusz Steczko;Boguslaw Stec;Zbyszek Otwinowski

  • Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures.

    Alexander Wlodawer;Wladek Minor;Zbigniew Dauter;Mariusz Jaskolski;Mariusz Jaskolski

  • Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion

    Hok-Kin Choi;Liang Tong;Wladek Minor;Philippe Dumas;Philippe Dumas

  • Data Mining of Metal Ion Environments Present in Protein Structures

    Heping Zheng;Maksymilian Chruszcz;Piotr Lasota;Lukasz Lebioda

  • CheckMyMetal: a macromolecular metal-binding validation tool.

    Heping Zheng;David R. Cooper;Przemyslaw J. Porebski;Ivan G. Shabalin

  • Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server

    Heping Zheng;Mahendra D Chordia;David R Cooper;Maksymilian Chruszcz;Maksymilian Chruszcz

  • Phosphorylation regulates SIRT1 function.

    Tsutomu Sasaki;Bernhard Maier;Katarzyna D. Koclega;Maksymilian Chruszcz

  • In situ proteolysis for protein crystallization and structure determination

    Aiping Dong;Xiaohui Xu;Aled M. Edwards;Changsoo Chang

  • A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.

    Natalia Beloglazova;Natalia Beloglazova;Greg Brown;Greg Brown;Matthew D. Zimmerman;Matthew D. Zimmerman;Michael Proudfoot;Michael Proudfoot

  • Crystal structure of RhoA–GDP and its functional implications

    Yunyi Wei;Yan Zhang;Urszula Derewenda;Xiaopu Liu

  • Asymmetric Synthesis of 2,3-Dihydro-2-arylquinazolin-4-ones: Methodology and Application to a Potent Fluorescent Tubulin Inhibitor with Anticancer Activity

    Gary M. Chinigo;Mikell Paige;Scott Grindrod;Ernest Hamel

  • Crystallographic Determination of the Active Site Iron and Its Ligands in Soybean Lipoxygenase L-1

    Wladek Minor;Janusz Steczko;Jeffrey T. Bolin;Zbyszek Otwinowski

  • The Enzyme Function Initiative

    John A. Gerlt;Karen N. Allen;Steven C. Almo;Richard N. Armstrong

  • The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity

    Yizhou Liu;Matthew D. Cheney;Justin J. Gaudet;Maksymilian Chruszcz

  • Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.

    Diana R. Tomchick;Phuc Phan;Marcin Cymborowski;Wladek Minor

Frequent Co-Authors

Alexei Savchenko
Alexei Savchenko University of Calgary
Mariusz Jaskolski
Mariusz Jaskolski Adam Mickiewicz University in Poznań
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Martin D. Chapman
Martin D. Chapman University of Virginia
Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
Helen M. Berman
Helen M. Berman Rutgers, The State University of New Jersey
Alexander Wlodawer
Alexander Wlodawer National Institutes of Health
John D. Westbrook
John D. Westbrook Rutgers, The State University of New Jersey
Torsten Schwede
Torsten Schwede University of Basel

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