World's Best Scientists 2026 revealed!
Mark Bartlam

Mark Bartlam

D-Index & Metrics

Chemistry

D-Index
48
Citations
13634
World Ranking
15048
National Ranking
2333

Overview

Mark Bartlam is affiliated with Nankai University in China, focusing their research primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Environmental Science. Their work spans multiple subfields including Molecular Biology, Pollution, Ecology, Materials Chemistry, and Genetics.

The scientist's research interests cover a diverse range of topics. These include:

  • Enzyme Structure and Function
  • Microbial Community Ecology and Physiology
  • Bacterial Genetics and Biotechnology
  • Genomics and Phylogenetic Studies
  • Biochemical and Molecular Research
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antibiotic Resistance in Bacteria

Mark Bartlam has contributed to several recent publications that reflect these areas of study. Notable papers include:

  • Polystyrene nanoparticles induce biofilm formation in Pseudomonas aeruginosa, 2024, Journal of Hazardous Materials
  • Integrated metagenomic and metatranscriptomic analysis reveals actively expressed antibiotic resistomes in the plastisphere, 2022, Journal of Hazardous Materials
  • Transcriptome Profiling of Stenotrophomonas sp. Strain WZN-1 Reveals Mechanisms of 2,2',4,4'-Tetrabromodiphenyl Ether (BDE-47) Biotransformation, 2022, Environmental Science & Technology
  • Characteristics, Biodiversity, and Cultivation Strategy of Low Nucleic Acid Content Bacteria, 2022, Frontiers in Microbiology
  • Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements, 2021, Protein Science

These papers cover topics such as antibiotic resistomes in environmental plastics, mechanisms of pollutant biotransformation by bacteria, bacterial biodiversity, biofilm formation induced by nanoparticles, and structural biology using advanced spectroscopy techniques.

Frequent collaborators of Mark Bartlam include:

  • Yingying Wang
  • Qionglin Zhang
  • Ruihua Liu
  • Yujing Chen

Their research outputs have been published in a variety of academic venues. Among the most frequent are:

  • Biochemical and Biophysical Research Communications
  • Journal of Hazardous Materials
  • The Science of The Total Environment
  • Environmental Science & Technology
  • Frontiers in Microbiology

Mark Bartlam's scientific work integrates molecular biology approaches with environmental science applications, exploring microbial genetics and biochemical pathways with an emphasis on enzyme functionality, bacterial community dynamics, and the environmental impact of antibiotics and pollutants.

Best Publications

  • Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

    Margaret Sunde;Louise C Serpell;Mark Bartlam;Paul E Fraser

  • The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

    Haitao Yang;Maojun Yang;Yi Ding;Yiwei Liu

  • Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II

    Fei Sun;Xia Huo;Yujia Zhai;Aojin Wang

  • Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

    Haitao Yang;Weiqing Xie;Xiaoyu Xue;Xiaoyu Xue;Kailin Yang;Kailin Yang

  • Selective enrichment of bacterial pathogens by microplastic biofilm.

    Xiaojian Wu;Jie Pan;Meng Li;Yao Li

  • Crystal structure of an avian influenza polymerase PA N reveals an endonuclease active site

    Puwei Yuan;Mark Bartlam;Zhiyong Lou;Shoudeng Chen

  • Insights into SARS-CoV transcription and replication from the structure of the nsp7–nsp8 hexadecamer

    Yujia Zhai;Fei Sun;Xuemei Li;Xuemei Li;Hai Pang

  • Structural insights into diversity and n-alkane biodegradation mechanisms of alkane hydroxylases.

    Yurui Ji;Guannan Mao;Yingying Wang;Mark Bartlam

  • Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction.

    Xiaoyu Xue;Haitao Yang;Haitao Yang;Wei Shen;Qi Zhao

  • Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase

    Liu Li;Xueqian Liu;Wen Yang;Feng Xu

  • New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.

    Bo Wang;Li-Ping Yang;Xiao-Zhuang Zhang;Shui-Qing Huang

  • 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.

    Beili Wu;Pengyun Li;Yiwei Liu;Zhiyong Lou

  • An Insight into the Mechanism of Human Cysteine Dioxygenase KEY ROLES OF THE THIOETHER-BONDED TYROSINE-CYSTEINE COFACTOR

    Sheng Ye;Xiao'ai Wu;Xiao'ai Wu;Lei Wei;Lei Wei;Danming Tang;Danming Tang

  • Crystal structure of methyl parathion hydrolase from Pseudomonas sp WBC-3

    Yan-Jie Dong;Mark Bartlam;Mark Bartlam;Lei Sun;Lei Sun;Ya-Feng Zhou

  • Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1.

    XX Zhang;SM Roe;YW Hou;M Bartlam

  • Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1)

    Xianjin Ou;Chaoneng Ji;Xueqing Han;Xiaodong Zhao

  • Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor.

    Hai Pang;Mark Bartlam;Qinghong Zeng;Hideyuki Miyatake

  • Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.

    Hui Wang;Hui Wang;Masahiro Morita;Xiuna Yang;Toru Suzuki

  • New Antiviral Target Revealed by the Hexameric Structure of Mouse Hepatitis Virus Nonstructural Protein nsp15

    Xiaoling Xu;Yujia Zhai;Yujia Zhai;Fei Sun;Fei Sun;Zhiyong Lou;Zhiyong Lou

  • Crystal Structure of an Acylpeptide Hydrolase/Esterase from Aeropyrum pernix K1

    Mark Bartlam;Ganggang Wang;Haitao Yang;Renjun Gao

Frequent Co-Authors

Zihe Rao
Zihe Rao Tsinghua University
Zhiyong Lou
Zhiyong Lou Tsinghua University
Wen Yang
Wen Yang Beijing Institute of Technology
Luet-Lok Wong
Luet-Lok Wong University of Oxford
George F. Gao
George F. Gao Chinese Center For Disease Control and Prevention
Feng Xu
Feng Xu Xi'an Jiaotong University
Tadashi Yamamoto
Tadashi Yamamoto Okinawa Institute of Science and Technology
Rongguang Zhang
Rongguang Zhang Chinese Academy of Sciences
Rolf Hilgenfeld
Rolf Hilgenfeld University of Lübeck
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory

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