World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
7469
World Ranking
18458
National Ranking
90

Overview

Yuh-Lien Chen is affiliated with National Taiwan University in Taiwan and conducts research primarily in the fields of biochemistry, genetics, molecular biology, and medicine. Their research output spans 28 publications in biochemistry, genetics, and molecular biology, alongside 25 contributions in medicine. Within these broad areas, Chen's subfields include molecular biology, health, toxicology and mutagenesis, pulmonary and respiratory medicine, cardiology and cardiovascular medicine, and epidemiology.

The main topics addressed in Chen's work cover a diverse range of biomedical and environmental health issues. These topics include air quality and health impacts, autophagy in disease and therapy, heme oxygenase-1 and carbon monoxide, extracellular vesicles in disease, climate change and health impacts, cardiovascular disease and adiposity, and mitochondrial function and pathology.

Chen has published a series of recent papers focusing on molecular mechanisms and cellular pathways related to disease and therapy. These include:

  • The crosstalk between copper-induced oxidative stress and cuproptosis: a novel potential anticancer paradigm (2024), published in Cell Communication and Signaling
  • Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway (2021), published in Theranostics
  • MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1 (2020), published in Frontiers in Cell and Developmental Biology
  • Particulate matters increase epithelial-mesenchymal transition and lung fibrosis through the ETS-1/NF-κB-dependent pathway in lung epithelial cells (2020), published in Particle and Fibre Toxicology
  • Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy (2020), published in Frontiers in Pharmacology

Frequent publication venues where Chen's work appears include:

  • Particle and Fibre Toxicology
  • Journal of Cancer
  • Biochemical Pharmacology
  • Cell Communication and Signaling
  • Theranostics

Chen collaborates extensively with several researchers, notably including I-Ta Lee, Thi Thuy Tien Vo, Tsai-Chun Lai, Chiang-Wen Lee, and Tzu-Lin Lee. These frequent coauthors reflect ongoing collaborative efforts across molecular biology and medical research disciplines.

Best Publications

  • CHONDROGENESIS OF HUMAN MESENCHYMAL STEM CELLS ENCAPSULATED IN ALGINATE BEADS

    Hsiao-Li Ma;Shih-Chieh Hung;Shan-Yang Lin;Yuh-Lien Chen

  • The cytotoxicity of corrosion products of nitinol stent wire on cultured smooth muscle cells

    Chun Che Shih;Shing Jong Lin;Yuh Lien Chen;Yea Yang Su

  • PM2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-κB-dependent pathway

    Chen Wei Liu;Tzu Lin Lee;Yu Chen Chen;Chan Jung Liang

  • Overexpression of HO-1 Protects against TNF-α-Mediated Airway Inflammation by Down-Regulation of TNFR1-Dependent Oxidative Stress

    I-Ta Lee;Shue Fen Luo;Chiang Wen Lee;Shyi Wu Wang

  • Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-alpha-treated human aortic endothelial cells.

    Yung Hsiang Chen;Shing Jong Lin;Hung Hai Ku;Ming Shi Shiao

  • Ginkgo biloba Extract Inhibits Tumor Necrosis Factor-α–Induced Reactive Oxygen Species Generation, Transcription Factor Activation, and Cell Adhesion Molecule Expression in Human Aortic Endothelial Cells

    Jaw Wen Chen;Yung Hsiang Chen;Feng Yan Lin;Yuh Lien Chen

  • Adipose-Derived Stem Cells Protect Skin Flaps against Ischemia/Reperfusion Injury via IL-6 Expression

    Chi Ming Pu;Chen Wei Liu;Chan Jung Liang;Yu Hsiu Yen

  • Superoxide Dismutase Inhibits the Expression of Vascular Cell Adhesion Molecule-1 and Intracellular Cell Adhesion Molecule-1 Induced by Tumor Necrosis Factor-α in Human Endothelial Cells Through the JNK/p38 Pathways

    Shing Jong Lin;Song Kun Shyue;Ya Yun Hung;Yung Hsiang Chen

  • Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-κB pathway and subsequently downregulating expression of matrix metalloproteinases

    Po Len Liu;Jong Rung Tsai;Albert Linton Charles;Jhi Jhu Hwang

  • Endothelial Progenitor Cell Dysfunction in Cardiovascular Diseases: Role of Reactive Oxygen Species and Inflammation

    Chih Pei Lin;Feng Yen Lin;Po Hsun Huang;Yuh Lien Chen

  • Magnolol attenuates VCAM-1 expression in vitro in TNF-α-treated human aortic endothelial cells and in vivo in the aorta of cholesterol-fed rabbits

    Yung Hsiang Chen;Shing Jong Lin;Shing Jong Lin;Jaw Wen Chen;Jaw Wen Chen;Hung Hai Ku

  • Curcumin accelerates cutaneous wound healing via multiple biological actions: The involvement of TNF-α, MMP-9, α-SMA, and collagen.

    Yu-Hsiu Yen;Yu-Hsiu Yen;Chi-Ming Pu;Chen-Wei Liu;Ya-Chun Chen

  • Anti-Inflammatory Effects of Different Drugs/Agents with Antioxidant Property on Endothelial Expression of Adhesion Molecules

    Yung Hsiang Chen;Shing Jong Lin;Yuh Lien Chen;Po Len Liu

  • High-mobility group box 1-mediated matrix metalloproteinase-9 expression in non-small cell lung cancer contributes to tumor cell invasiveness.

    Po Len Liu;Jong Rung Tsai;Jhi Jhu Hwang;Shah Hwa Chou

  • Wood smoke extract induces oxidative stress-mediated caspase-independent apoptosis in human lung endothelial cells: role of AIF and EndoG

    Po Len Liu;Yuh Lien Chen;Yung Hsiang Chen;Shing Jong Lin

  • Localization and characterization of a novel secreted protein SCUBE1 in human platelets

    Cheng Fen Tu;Yueh Hsing Su;Ya Ni Huang;Ming Tzu Tsai

  • Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

    Jing Zhou;Pei Ling Lee;Chien Sung Tsai;Chih I. Lee

  • Endotoxin Induces Toll-Like Receptor 4 Expression in Vascular Smooth Muscle Cells via NADPH Oxidase Activation and Mitogen-Activated Protein Kinase Signaling Pathways

    Feng Yen Lin;Yung Hsiang Chen;Jen Sung Tasi;Jaw Wen Chen

  • Salvianolic acid B attenuates MMP-2 and MMP-9 expression in vivo in apolipoprotein-E-deficient mouse aorta and in vitro in LPS-treated human aortic smooth muscle cells.

    Shing Jong Lin;I-Ta Lee;Yung Hsiang Chen;Feng Yen Lin

  • The Role of Human Antigen R, an RNA-binding Protein, in Mediating the Stabilization of Toll-Like Receptor 4 mRNA Induced by Endotoxin A Novel Mechanism Involved in Vascular Inflammation

    Feng Yen Lin;Yung Hsiang Chen;Yi Wen Lin;Jen Sung Tsai

Frequent Co-Authors

Shing Jong Lin
Shing Jong Lin Taipei Veterans General Hospital
Shu Chien
Shu Chien University of California, San Diego
Chuen-Mao Yang
Chuen-Mao Yang Chang Gung University
Lee-Ming Chuang
Lee-Ming Chuang National Taiwan University
Sung-Tsang Hsieh
Sung-Tsang Hsieh National Taiwan University
Shun Hua Chen
Shun Hua Chen National Cheng Kung University
Fuu Jen Tsai
Fuu Jen Tsai China Medical University
Ching-Shih Chen
Ching-Shih Chen The Ohio State University
Ruey-Bing Yang
Ruey-Bing Yang Academia Sinica
Shih-Chieh Hung
Shih-Chieh Hung China Medical University

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