World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
24106
World Ranking
6532
National Ranking
499

Overview

Louise C. Serpell is affiliated with the University of Sussex in the United Kingdom. Their research spans multiple fields, primarily within biochemistry, genetics, and molecular biology, with a significant focus on medicine. The scientist's contributions are notably grounded in molecular biology, physiology, and cellular and molecular neuroscience, alongside work in biomaterials and materials chemistry.

The research topics covered by Louise C. Serpell include:

  • Alzheimer's disease research and treatments
  • Prion diseases and protein misfolding
  • Supramolecular self-assembly in materials
  • Neuroscience and neuropharmacology research
  • Protein structure and dynamics
  • Advanced neuroimaging techniques and applications
  • CRISPR and genetic engineering

Louise C. Serpell has authored multiple recent papers, some of which include:

  • Half a century of amyloids: past, present and future, 2020, Chemical Society Reviews
  • Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target, 2020, Frontiers in Neurology
  • Misfolded amyloid-β-42 impairs the endosomal-lysosomal pathway, 2020, Cellular and Molecular Life Sciences
  • Internalisation and toxicity of amyloid-β 1-42 are influenced by its conformation and assembly state rather than size, 2020, FEBS Letters
  • Quantification of amyloid fibril polymorphism by nano-morphometry reveals the individuality of filament assembly, 2020, Communications Chemistry

Frequent co-authors collaborating with Louise C. Serpell include:

  • Youssra K. Al-Hilaly
  • Mahmoud Bukar Maina
  • Karen E. Marshall
  • Claude M. Wischik
  • Wei-Feng Xue

The scientist has published regularly in several key venues, with multiple works appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Molecular Biology
  • Alzheimer's & Dementia
  • The Cambridge Structural Database
  • Research Square (Research Square)

Best Publications

  • Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

    Margaret Sunde;Louise C Serpell;Mark Bartlam;Paul E Fraser

  • Nucleated conformational conversion and the replication of conformational information by a prion determinant.

    Tricia R. Serio;Anil G. Cashikar;Anthony S. Kowal;George J. Sawicki

  • Distinct tau prion strains propagate in cells and mice and define different tauopathies.

    David W. Sanders;Sarah K. Kaufman;Sarah L. DeVos;Apurwa M. Sharma

  • Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation.

    L C Serpell;J Berriman;R Jakes;M Goedert

  • Molecular basis for amyloid fibril formation and stability

    O. Sumner Makin;Edward Atkins;Pawel Sikorski;Jan Johansson

  • Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

    Sebastian Maurer-Stroh;Maja Debulpaep;Maja Debulpaep;Nico Kuemmerer;Manuela Lopez de la Paz

  • Structures for amyloid fibrils.

    O. Sumner Makin;Louise C. Serpell

  • Amyloid fibrils: abnormal protein assembly.

    Roma N Rambaran;Louise C Serpell

  • Half a century of amyloids: past, present and future

    Pu Chun Ke;Pu Chun Ke;Ruhong Zhou;Ruhong Zhou;Louise C. Serpell;Roland Riek

  • Rational design and application of responsive α-helical peptide hydrogels

    Eleanor F. Banwell;Edgardo S. Abelardo;Edgardo S. Abelardo;Dave J. Adams;Martin A. Birchall

  • The Helix-Hairpin-Helix DNA-Binding Motif: A Structural Basis for Non-Sequence-Specific Recognition of DNA

    Aidan J. Doherty;Louise C. Serpell;Christopher P. Ponting

  • The protofilament substructure of amyloid fibrils.

    Louise C Serpell;Margaret Sunde;Merrill D Benson;Glenys A Tennent

  • Proteasomal degradation of tau protein.

    Della C. David;Robert Layfield;Louise Serpell;Yolanda Narain

  • Membrane and surface interactions of Alzheimer's Aβ peptide--insights into the mechanism of cytotoxicity.

    Thomas L. Williams;Louise C. Serpell

  • Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-β structure

    John Berriman;Louise C. Serpell;Keith A. Oberg;Anthony L. Fink

  • Protofilaments, filaments, ribbons, and fibrils from peptidomimetic self-assembly: Implications for amyloid fibril formation and materials science

    Hilal A. Lashuel;Steven R. LaBrenz;Linda Woo;Louise C. Serpell

  • Mutation E46K increases phospholipid binding and assembly into filaments of human α-synuclein

    Woong Choi;Shahin Zibaee;Ross Jakes;Louise C. Serpell

  • Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis.

    Emma T.A.S Jaikaran;Claire E Higham;Louise C Serpell;Jesús Zurdo

  • Structural Basis for Increased Toxicity of Pathological Aβ42:Aβ40 Ratios in Alzheimer Disease

    Kris Pauwels;Thomas L. Williams;Kyle L. Morris;Wim Jonckheere;Wim Jonckheere

  • Engineering nanoscale order into a designed protein fiber

    David Papapostolou;Andrew M. Smith;Edward D. T. Atkins;Seb J. Oliver

Frequent Co-Authors

Dave J. Adams
Dave J. Adams University of Glasgow
Paul E. Fraser
Paul E. Fraser University of Toronto
Margaret Sunde
Margaret Sunde University of Sydney
Alison Rodger
Alison Rodger Macquarie University
Kevin Staras
Kevin Staras University of Sussex
Mick F. Tuite
Mick F. Tuite University of Kent
Timothy R. Dafforn
Timothy R. Dafforn University of Birmingham
Michel Goedert
Michel Goedert MRC Laboratory of Molecular Biology
Thomas Scheibel
Thomas Scheibel University of Bayreuth

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring careers in Biology and Biochemistry opens the door to a variety of flexible online degree programs and healthcare pathways. For those interested in entry-level healthcare roles, online medical assistant programs that accept financial aid offer an accessible route with financial support options. Medical assistants can further enhance their qualifications by enrolling in a medical assistant to lpn bridge program online, paving the way for higher responsibility and increased earning potential.

If you aim to deepen your understanding of biological sciences, consider enrolling in a biology degree online. These accelerated programs help you fast-track your studies while maintaining flexibility for work or personal commitments. For those drawn to patient care, registered nurse online programs deliver a solid foundation leading to a rewarding nursing career. No matter your starting point, online education in biology, nursing, or allied health can streamline your professional journey and expand your opportunities in the medical and scientific fields.

Best Scientists Citing Louise C. Serpell

Trending Scientists