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Chemistry

D-Index
58
Citations
12429
World Ranking
10587
National Ranking
89

Overview

Thomas Lars Andresen is affiliated with the Technical University of Denmark in Denmark. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Immunology, Biomedical Engineering, Biomaterials, and Oncology as subfields of study.

The scientist's work addresses several main topics, including:

  • RNA Interference and Gene Delivery
  • Immunotherapy and Immune Responses
  • Nanoparticle-Based Drug Delivery
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Monoclonal and Polyclonal Antibodies Research
  • Nanoplatforms for cancer theranostics

Frequent co-authors found in Andresen's publications include Anders E. Hansen, Paul J. Kempen, Jonas R. Henriksen, Andreas Kjær, and Gael Clergeaud, demonstrating collaborative work across multiple studies.

The scientist's publication record includes several papers in established journals, illustrating areas of interest and contribution. Some recent papers are:

  • The Manufacture of Unbreakable Bionics via Multifunctional and Self-Healing Silk-Graphene Hydrogels (2021, Advanced Materials)
  • Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles (2021, Nature Communications)
  • Soft Electronic Materials with Combinatorial Properties Generated via Mussel-Inspired Chemistry and Halloysite Nanotube Reinforcement (2021, ACS Nano)
  • Tumor repolarization by an advanced liposomal drug delivery system provides a potent new approach for chemo-immunotherapy (2020, Science Advances)
  • Cell surface-tethered IL-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy (2022, Science Advances)

Andresen frequently publishes in several scientific venues, with the highest number of contributions appearing in the Journal of Controlled Release and bioRxiv (Cold Spring Harbor Laboratory). Other notable publication venues include Regular and Young Investigator Award Abstracts, ACS Applied Materials & Interfaces, and International Journal of Pharmaceutics.

Best Publications

  • The Possible “Proton Sponge ” Effect of Polyethylenimine (PEI) Does Not Include Change in Lysosomal pH

    Rikke V Benjaminsen;Maria A Mattebjerg;Jonas R Henriksen;S Moein Moghimi

  • Advanced strategies in liposomal cancer therapy: problems and prospects of active and tumor specific drug release.

    Thomas Lars Andresen;Simon Skøde Jensen;Kent Jørgensen

  • Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

    Seyed Moghimi;A. C. Hunter;T. L. Andresen

  • In vivo toxicity of cationic micelles and liposomes.

    Kristina Bram Knudsen;Kristina Bram Knudsen;Helle Northeved;Pramod Kumar Ek;Anders Permin

  • Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering.

    Islam Hamad;Othman Al-Hanbali;A. Christy Hunter;Kenneth J. Rutt

  • Material properties in complement activation.

    S. Moein Moghimi;Alina Joukainen Andersen;Davoud Ahmadvand;Peter P. Wibroe

  • What is the blood concentration of extracellular vesicles?: Implications for the use of extracellular vesicles as blood-borne biomarkers of cancer

    Kasper Bendix Johnsen;Johann Mar Gudbergsson;Thomas Lars Andresen;Jens Bæk Simonsen

  • Methylation of the phosphate oxygen moiety of phospholipid-methoxy(polyethylene glycol) conjugate prevents PEGylated liposome-mediated complement activation and anaphylatoxin production

    S. Moein Moghimi;Islam Hamad;Thomas L. Andresen;Kent Jørgensen

  • Positron Emission Tomography Based Elucidation of the Enhanced Permeability and Retention Effect in Dogs with Cancer Using Copper-64 Liposomes.

    Anders E Hansen;Anncatrine L Petersen;Jonas R Henriksen;Betina Boerresen

  • Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma.

    Kasper Bendix Johnsen;Kasper Bendix Johnsen;Annette Burkhart;Fredrik Melander;Paul Joseph Kempen

  • Polycation cytotoxicity: a delicate matter for nucleic acid therapy-focus on polyethylenimine

    Ladan Parhamifar;Anna K. Larsen;A. Christy Hunter;Thomas Lars Andresen

  • Enzyme-triggered nanomedicine: Drug release strategies in cancer therapy (Invited Review)

    Thomas Lars Andresen;David H. Thompson;Thomas Kaasgaard

  • Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs.

    Thomas L. Andresen;Jesper Davidsen;Mikael Begtrup;Ole G. Mouritsen

  • Evaluating nanoparticle sensor design for intracellular pH measurements.

    Rikke Vicki Benjaminsen;Honghao Sun;Jonas Rosager Henriksen;Nynne Meyn Christensen

  • Complement activation cascade triggered by PEG-PL engineered nanomedicines and carbon nanotubes: The challenges ahead.

    S.M. Moghimi;Alina Joukainen Andersen;S.H. Hashemi;B. Lettiero

  • Liposome imaging agents in personalized medicine.

    Anncatrine Luisa Petersen;Anders Elias Hansen;Alberto Gabizon;Thomas Lars Andresen

  • Secreted phospholipase A2 as a new enzymatic trigger mechanism for localised liposomal drug release and absorption in diseased tissue

    Jesper Davidsen;Kent Jørgensen;Thomas L. Andresen;Ole G. Mouritsen

  • Revisit complexation between DNA and polyethylenimine--effect of length of free polycationic chains on gene transfection.

    Yanan Yue;Fan Jin;Rui Deng;Jinge Cai

  • Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo.

    Kasper Bendix Johnsen;Martin Bak;Fredrik Melander;Maj Schneider Thomsen

  • Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles.

    Kasper Bendix Johnsen;Martin Bak;Paul Joseph Kempen;Fredrik Melander

  • A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies

    Hsih-Yin Tan;Hsih-Yin Tan;Sofie Trier;Ulrik L Rahbek;Martin Dufva

  • Elucidating the interplay between DNA-condensing and free polycations in gene transfection through a mechanistic study of linear and branched PEI

    Zhuojun Dai;Torben Gjetting;Maria Ahlm Mattebjerg;Chi Wu

  • Single-walled carbon nanotube surface control of complement recognition and activation.

    Alina Joukainen Andersen;Joshua T. Robinson;Hongjie Dai;A. Christy Hunter

  • Understanding Detergent Effects on Lipid Membranes: A Model Study of Lysolipids

    Jonas Rosager Henriksen;Thomas Lars Andresen;Lise Nørkjær Feldborg;L. Duelund

  • Design, synthesis, structural and functional characterization of novel melanocortin agonists based on the cyclotide kalata B1

    Rasmus Eliasen;Norelle L. Daly;Norelle L. Daly;Birgitte S. Wulff;Thomas L. Andresen

  • Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats

    Kristina Bram Knudsen;Kristina Bram Knudsen;Helle Northeved;Torben Gjetting;Anders Permin

  • Secretory phospholipase A2 as a tumor-specific trigger for targeted delivery of a novel class of liposomal prodrug anticancer etherlipids.

    Simon S Jensen;Thomas L Andresen;Jesper Davidsen;Pernille Høyrup

Frequent Co-Authors

Andreas Kjaer
Andreas Kjaer University of Copenhagen
Torben Moos
Torben Moos Aalborg University
Kristoffer Almdal
Kristoffer Almdal Technical University of Denmark
Alireza Dolatshahi-Pirouz
Alireza Dolatshahi-Pirouz Technical University of Denmark
Robert Madsen
Robert Madsen Technical University of Denmark
Jenny Emnéus
Jenny Emnéus Technical University of Denmark
Niels Bent Larsen
Niels Bent Larsen Technical University of Denmark
Günther H.J. Peters
Günther H.J. Peters Technical University of Denmark
Mehdi Mehrali
Mehdi Mehrali Technical University of Denmark
Bruce D. Walker
Bruce D. Walker Harvard University

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