Bart O. Williams

Overview

Best Publications

• Tumor spectrum analysis in p53-mutant mice.

  Tyler Jacks;Lee Remington;Bart O. Williams;Earlene M. Schmitt

  2493
  Citations

• TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

  Ken Inoki;Hongjiao Ouyang;Tianqing Zhu;Charlotta Lindvall

  1558
  Citations

• Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

  Maria Domenica Castellone;Hidemi Teramoto;Bart O. Williams;Kirk M. Druey

  1096
  Citations

• p53 -dependent apoptosis produced by Rb -deficiency in the developing mouse lens

  Sharon D. Morgenbesser;Bart O. Williams;Tyler Jacks;Ronald A. DePinho

  798
  Citations

• A subset of p53-deficient embryos exhibit exencephaly.

  Valerie P. Sah;Laura D. Attardi;George J. Mulligan;Bart O. Williams

  731
  Citations

• Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization

  Julien Sage;George J. Mulligan;Laura D. Attardi;Abigail Miller

  730
  Citations

• Essential Role of β-Catenin in Postnatal Bone Acquisition

  Sheri L. Holmen;Cassandra R. Zylstra;Aditi Mukherjee;Robert E. Sigler

  703
  Citations

• Cooperative tumorigenic effects of germline mutations in Rb and p53.

  Bart O. Williams;Lee Remington;Daniel M. Albert;Shizuo Mukai

  489
  Citations

• p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.

  Robbert J. C. Slebos;Mann H. Lee;Beverly S. Plunkett;Theodore D. Kessis

  482
  Citations

• Lrp5 functions in bone to regulate bone mass

  Yajun Cui;Paul J Niziolek;Paul J Niziolek;Bryan T MacDonald;Cassandra R Zylstra

  470
  Citations

• Targeted disruption of p107: functional overlap between p107 and Rb.

  M H Lee;B O Williams;G Mulligan;S Mukai

  458
  Citations

• Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.

  Sheri L Holmen;Troy A Giambernardi;Cassandra R Zylstra;Bree D Buckner-Berghuis

  414
  Citations

• Regulation of Wnt Signaling by Sox Proteins: XSox17α/β and XSox3 Physically Interact with β-catenin

  Aaron M Zorn;Grant D Barish;Bart O Williams;Paul Lavender;Paul Lavender

  414
  Citations

• mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging

  Rogerio M. Castilho;Cristiane H. Squarize;Lewis A. Chodosh;Bart O. Williams

  413
  Citations

• Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts.

  R E Herrera;V P Sah;B O Williams;T P Mäkelä

  396
  Citations

• Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/−) mice

  Lili Yamasaki;Roderick Bronson;Bart O. Williams;Nicholas J. Dyson

  376
  Citations

• Mouse Model of Human Ovarian Endometrioid Adenocarcinoma Based on Somatic Defects in the Wnt/β-Catenin and PI3K/Pten Signaling Pathways

  Rong Wu;Neali Hendrix-Lucas;Rork Kuick;Yali Zhai

  372
  Citations

• Extensive contribution of Rb‐deficient cells to adult chimeric mice with limited histopathological consequences.

  Bart O. Williams;Earlene M. Schmitt;Lee Remington;Roderick T. Bronson

  342
  Citations

• Mouse Model of Colonic Adenoma-Carcinoma Progression Based on Somatic Apc Inactivation

  Takao Hinoi;Aytekin Akyol;Brian K. Theisen;David O. Ferguson

  336
  Citations

• Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts

  Zahra Kabiri;Gediminas Greicius;Babita Madan;Steffen Biechele

  331
  Citations