Lawrence A. Donehower focuses on Cancer research, Carcinogenesis, Genetics, Tumor suppressor gene and Gene. The various areas that Lawrence A. Donehower examines in his Cancer research study include Mutation, Microsatellite instability, Mdm2, Signal transduction and Gene targeting. His Carcinogenesis research is multidisciplinary, incorporating elements of Transgene, Immunology, Germline, Molecular biology and Allele.
His Gene research is multidisciplinary, incorporating perspectives in Liver cancer and Mutation. The DNA methylation study combines topics in areas such as microRNA, Epigenetics and Genomics. He has included themes like Genetic heterogeneity and MicroRNA sequencing in his Cancer study.
Lawrence A. Donehower mainly focuses on Cancer research, Carcinogenesis, Molecular biology, Gene and Genetics. His Cancer research study combines topics in areas such as Tumor suppressor gene, Cancer, Allele and Transgene. Lawrence A. Donehower has researched Carcinogenesis in several fields, including Lymphoma, Immunology, Ratón, Knockout mouse and Null allele.
His Molecular biology study integrates concerns from other disciplines, such as DNA, DNA damage, DNA repair, Carcinogen and Wild type. Lawrence A. Donehower studies Gene, focusing on DNA methylation in particular. In his study, which falls under the umbrella issue of Mutant, Stem cell is strongly linked to Mutation.
His primary areas of study are Cancer research, Gene, Osteosarcoma, Cancer and microRNA. His study in Cancer research is interdisciplinary in nature, drawing from both DNA damage, Oncogene, Microsatellite instability, KRAS and Sarcoma. His Gene study deals with the bigger picture of Genetics.
His work on Breast cancer as part of general Cancer study is frequently linked to Context, bridging the gap between disciplines. Lawrence A. Donehower has researched Breast cancer in several fields, including Genetic heterogeneity and MicroRNA sequencing. His microRNA research includes elements of Disease, DNA methylation and Bioinformatics.
Lawrence A. Donehower mostly deals with Cancer research, Gene, Genetics, microRNA and DNA methylation. His Cancer research study incorporates themes from Mutation, Oncogene, Microsatellite instability and Transcription factor. Lawrence A. Donehower studied Gene and Liver cancer that intersect with DNA sequencing, DNA Mutational Analysis, PI3K/AKT/mTOR pathway and CpG site.
His research integrates issues of Mitochondrial DNA, Point mutation and Somatic cell in his study of DNA methylation. His studies examine the connections between Loss of heterozygosity and genetics, as well as such issues in Tumor suppressor gene, with regards to Chromosome instability. His studies in Exome integrate themes in fields like Breast cancer and Triple-negative breast cancer.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Comprehensive molecular portraits of human breast tumours
Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt.
Nature (2012)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir.
Nature (2008)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh.
Nature (2012)
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Lawrence A. Donehower;Michele Harvey;Betty L. Slagle;Mark J. McArthur.
Nature (1992)
The cancer genome atlas pan-cancer analysis project
John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw.
Nature Genetics (2013)
Comprehensive molecular characterization of urothelial bladder carcinoma
John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang.
Nature (2014)
Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint
Qinghua Liu;Saritha Guntuku;Xian Shu Cui;Shuhei Matsuoka.
Genes & Development (2000)
p53 mutant mice that display early ageing-associated phenotypes
Stuart D. Tyner;Sundaresan Venkatachalam;Jene Choi;Stephen Jones.
Nature (2002)
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
Stephen N. Jones;Amy E. Roe;Lawrence A. Donehower;Allan Bradley.
Nature (1995)
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf.
Cell (2018)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
Kymab (United Kingdom)
Baylor College of Medicine
Baylor College of Medicine
Baylor College of Medicine
Indiana University
The University of Texas MD Anderson Cancer Center
Nationwide Children's Hospital
Baylor College of Medicine
Broad Institute
Memorial Sloan Kettering Cancer Center
Stanford University
Universiti Tenaga Nasional
Northumbria University
Medical University of Graz
Fuzhou University
Linköping University
United States Department of Agriculture
University of Hawaii at Manoa
RIKEN
University of Ulm
Australian National University
Johns Hopkins University
National Institutes of Health
National Institutes of Health
City, University of London