D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 84 Citations 65,011 204 World Ranking 9775 National Ranking 5171
Molecular Biology D-index 82 Citations 64,727 203 World Ranking 559 National Ranking 314

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Lawrence A. Donehower focuses on Cancer research, Carcinogenesis, Genetics, Tumor suppressor gene and Gene. The various areas that Lawrence A. Donehower examines in his Cancer research study include Mutation, Microsatellite instability, Mdm2, Signal transduction and Gene targeting. His Carcinogenesis research is multidisciplinary, incorporating elements of Transgene, Immunology, Germline, Molecular biology and Allele.

His Gene research is multidisciplinary, incorporating perspectives in Liver cancer and Mutation. The DNA methylation study combines topics in areas such as microRNA, Epigenetics and Genomics. He has included themes like Genetic heterogeneity and MicroRNA sequencing in his Cancer study.

His most cited work include:

  • Comprehensive molecular portraits of human breast tumours (7253 citations)
  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways (5484 citations)
  • Comprehensive molecular characterization of human colon and rectal cancer (5012 citations)

What are the main themes of his work throughout his whole career to date?

Lawrence A. Donehower mainly focuses on Cancer research, Carcinogenesis, Molecular biology, Gene and Genetics. His Cancer research study combines topics in areas such as Tumor suppressor gene, Cancer, Allele and Transgene. Lawrence A. Donehower has researched Carcinogenesis in several fields, including Lymphoma, Immunology, Ratón, Knockout mouse and Null allele.

His Molecular biology study integrates concerns from other disciplines, such as DNA, DNA damage, DNA repair, Carcinogen and Wild type. Lawrence A. Donehower studies Gene, focusing on DNA methylation in particular. In his study, which falls under the umbrella issue of Mutant, Stem cell is strongly linked to Mutation.

He most often published in these fields:

  • Cancer research (46.01%)
  • Carcinogenesis (24.88%)
  • Molecular biology (23.47%)

What were the highlights of his more recent work (between 2011-2021)?

  • Cancer research (46.01%)
  • Gene (20.66%)
  • Osteosarcoma (8.92%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cancer research, Gene, Osteosarcoma, Cancer and microRNA. His study in Cancer research is interdisciplinary in nature, drawing from both DNA damage, Oncogene, Microsatellite instability, KRAS and Sarcoma. His Gene study deals with the bigger picture of Genetics.

His work on Breast cancer as part of general Cancer study is frequently linked to Context, bridging the gap between disciplines. Lawrence A. Donehower has researched Breast cancer in several fields, including Genetic heterogeneity and MicroRNA sequencing. His microRNA research includes elements of Disease, DNA methylation and Bioinformatics.

Between 2011 and 2021, his most popular works were:

  • Comprehensive molecular portraits of human breast tumours (7253 citations)
  • Comprehensive molecular characterization of human colon and rectal cancer (5012 citations)
  • The cancer genome atlas pan-cancer analysis project (3506 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Lawrence A. Donehower mostly deals with Cancer research, Gene, Genetics, microRNA and DNA methylation. His Cancer research study incorporates themes from Mutation, Oncogene, Microsatellite instability and Transcription factor. Lawrence A. Donehower studied Gene and Liver cancer that intersect with DNA sequencing, DNA Mutational Analysis, PI3K/AKT/mTOR pathway and CpG site.

His research integrates issues of Mitochondrial DNA, Point mutation and Somatic cell in his study of DNA methylation. His studies examine the connections between Loss of heterozygosity and genetics, as well as such issues in Tumor suppressor gene, with regards to Chromosome instability. His studies in Exome integrate themes in fields like Breast cancer and Triple-negative breast cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt.
Nature (2012)

8574 Citations

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir.
Nature (2008)

6113 Citations

Comprehensive molecular characterization of human colon and rectal cancer

Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh.
Nature (2012)

6063 Citations

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower;Michele Harvey;Betty L. Slagle;Mark J. McArthur.
Nature (1992)

5967 Citations

The cancer genome atlas pan-cancer analysis project

John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw.
Nature Genetics (2013)

4865 Citations

Comprehensive molecular characterization of urothelial bladder carcinoma

John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang.
Nature (2014)

3213 Citations

Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint

Qinghua Liu;Saritha Guntuku;Xian Shu Cui;Shuhei Matsuoka.
Genes & Development (2000)

2036 Citations

p53 mutant mice that display early ageing-associated phenotypes

Stuart D. Tyner;Sundaresan Venkatachalam;Jene Choi;Stephen Jones.
Nature (2002)

1674 Citations

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Stephen N. Jones;Amy E. Roe;Lawrence A. Donehower;Allan Bradley.
Nature (1995)

1593 Citations

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf.
Cell (2018)

1341 Citations

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