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Nicholas J. Dyson

Nicholas J. Dyson

D-Index & Metrics

Molecular Biology

D-Index
95
Citations
41097
World Ranking
627
National Ranking
342

Overview

Nicholas J. Dyson is affiliated with Harvard University in the United States. Their research spans several areas within biochemistry, genetics, and molecular biology, with a significant focus on medicine-related studies. This work includes a specialization in molecular biology and oncology, with emphasis on cancer research and pulmonary and respiratory medicine.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, the primary subfields of research are:

  • Molecular Biology
  • Oncology
  • Cancer Research
  • Pulmonary and Respiratory Medicine
  • Genetics

The major topics covered in Dyson's work are diverse within cancer biology and genetics, incorporating aspects such as:

  • Epigenetics and DNA Methylation
  • Cancer-related Molecular Pathways
  • Genomics and Chromatin Dynamics
  • Lung Cancer Research Studies
  • Cancer therapeutics and mechanisms
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer

The scientist has published multiple papers in various scientific journals and platforms. Some of the notable recent publications include:

  • Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer, 2021, Nature Communications
  • Therapy-induced APOBEC3A drives evolution of persistent cancer cells, 2023, Nature
  • Clinical Outcomes With Abemaciclib After Prior CDK4/6 Inhibitor Progression in Breast Cancer: A Multicenter Experience, 2021, Journal of the National Comprehensive Cancer Network
  • Acquired Cross-Resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC Paralogs, 2024, Cancer Discovery
  • Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer, 2022, Science Advances

Dyson frequently collaborates with other researchers in their field. The most common co-authors associated with their work include:

  • Michael S. Lawrence
  • Ioannis Sanidas
  • Marcello Stanzione
  • Benjamin J. Drapkin
  • Anna F. Farago

Dyson's articles often appear in notable academic venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • UNC Libraries
  • Communications Biology
  • Nature Communications

Best Publications

  • The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

    Nicholas Dyson;Peter M. Howley;Karl Münger;Ed Harlow

  • The regulation of E2F by pRB-family proteins

    Nicholas Dyson

  • Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

    K Münger;B A Werness;N Dyson;W C Phelps

  • Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1

    Lili Yamasaki;Tyler Jacks;Roderick Bronson;Evelyne Goillot

  • The E2F transcriptional network: old acquaintances with new faces.

    Desssislava K Dimova;Nicholas J Dyson

  • MyoD is required for myogenic stem cell function in adult skeletal muscle.

    L A Megeney;B Kablar;K Garrett;J E Anderson

  • A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

    Kristian Helin;Jacqueline A. Lees;Marc Vidal;Nicholas Dyson

  • Insulin-like Growth Factor Receptor I Mediates Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Primary Human Glioblastoma Cells through Continued Activation of Phosphoinositide 3-Kinase Signaling

    Arnab Chakravarti;Jay S Loeffler;Nicholas J Dyson

  • Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.

    Rushika M. Perera;Svetlana Stoykova;Brandon N. Nicolay;Kenneth N. Ross

  • Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.

    Liang Zhu;S. Van Den Heuvel;K. Helin;Ali Fattaey

  • pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

    R K Hurford;D Cobrinik;M H Lee;N Dyson

  • Shared role of the pRB-related p130 and p107 proteins in limb development.

    David Cobrinik;Myung-Ho Lee;Gregory Hannon;George Mulligan

  • The retinoblastoma protein binds to a family of E2F transcription factors.

    J A Lees;M Saito;M Vidal;M Valentine

  • A revised picture of the E2F transcriptional network and RB function.

    Olivier Stevaux;Nicholas J Dyson

  • Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

    Maxim V. Frolov;Nicholas J. Dyson

  • Conserved functions of the pRB and E2F families

    Sander van den Heuvel;Nicholas J. Dyson

  • A novel retinoblastoma therapy from genomic and epigenetic analyses

    Jinghui Zhang;Claudia A. Benavente;Justina McEvoy;Jacqueline Flores-Otero

  • Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins.

    N Dyson;P Guida;K Münger;E Harlow

  • Quantitatively Determined Survivin Expression Levels Are of Prognostic Value in Human Gliomas

    Arnab Chakravarti;Elizabeth Noll;Peter McL. Black;Daniel F. Finkelstein

  • Retinoblastoma protein partners.

    Erick J. Morris;Nicholas J. Dyson

Frequent Co-Authors

Ed Harlow
Ed Harlow Harvard University
Wilhelm Haas
Wilhelm Haas Harvard University
Daniel A. Haber
Daniel A. Haber Harvard University
Nabeel Bardeesy
Nabeel Bardeesy Harvard University
Mari Mino-Kenudson
Mari Mino-Kenudson Harvard University
Alice T. Shaw
Alice T. Shaw Harvard University
Shyamala Maheswaran
Shyamala Maheswaran Harvard University
Sridhar Ramaswamy
Sridhar Ramaswamy Harvard University
Marc Vidal
Marc Vidal Harvard University

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