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Chemistry

D-Index
82
Citations
52236
World Ranking
3026
National Ranking
1008

Overview

Valery V. Fokin is affiliated with the University of Southern California in the United States and has a research focus primarily concentrated in the fields of Materials Science and Chemistry. Their scholarly activities integrate subfields such as Materials Chemistry, Organic Chemistry, Biomedical Engineering, Electrochemistry, and Electrical and Electronic Engineering.

Their work extensively covers topics including Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Click Chemistry and Applications, Cyclopropane Reaction Mechanisms, Electrochemical Analysis and Applications, Sulfur-Based Synthesis Techniques, and Innovative Microfluidic and Catalytic Techniques Innovation.

Fokin has contributed significantly to scientific literature, with a selection of recent publications that highlight their research interests. These include:

  • On-Water Selectivity Switch in Microdroplets in the 1,2,3-Triazole Synthesis from Bromoethenesulfonyl Fluoride, 2021, Journal of the American Chemical Society
  • Sulfuryl Fluoride Mediated Synthesis of Amides and Amidines from Ketoximes via Beckmann Rearrangement, 2020, Chemistry - A European Journal
  • Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis, 2020, PLoS neglected tropical diseases
  • Virtual Screening of a Chemically Diverse "Superscaffold" Library Enables Ligand Discovery for a Key GPCR Target, 2024, ACS Chemical Biology
  • Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis, 2021, Journal of Medicinal Chemistry

The University of Southern California serves as their primary institutional base, supporting research that frequently appears in venues such as The Cambridge Structural Database, Journal of the American Chemical Society, Angewandte Chemie International Edition, Chemistry - A European Journal, and PLoS neglected tropical diseases.

Frequent collaborators in their research include Antonina L. Nazarova, Billal Zayat, Sri Narayan, Dmitry B. Eremin, and Shubhangi Aggarwal, reflecting a network of research partnerships with ongoing contributions in overlapping thematic areas.

Best Publications

  • A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes.

    Vsevolod V. Rostovtsev;Luke G. Green;Valery V. Fokin;K. Barry Sharpless

  • Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides

    Jason E. Hein;Valery V. Fokin

  • Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates.

    Fahmi Himo;Timothy Lovell;Robert Hilgraf;Vsevolod V Rostovtsev

  • Bioconjugation by Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition

    Qian Wang;Timothy R Chan;Robert Hilgraf;Valery V Fokin

  • Polytriazoles as copper(I)-stabilizing ligands in catalysis.

    Timothy R Chan;Robert Hilgraf;K Barry Sharpless;Valery V Fokin

  • “On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension

    Sridhar Narayan;John Muldoon;M. G. Finn;Valery V. Fokin

  • Organic Synthesis “On Water”

    Arani Chanda;Valery V. Fokin

  • Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

    Peng Wu;Alina K. Feldman;Anne K. Nugent;Craig J. Hawker

  • Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism.

    Brant C. Boren;Sridhar Narayan;Lars K. Rasmussen;Li Zhang

  • Direct evidence of a dinuclear copper intermediate in Cu(I)-catalyzed azide-alkyne cycloadditions.

    B. T. Worrell;J. A. Malik;V. V. Fokin

  • Mechanism of the Ligand-Free CuI-Catalyzed Azide–Alkyne Cycloaddition Reaction†

    Valentin O. Rodionov;Valery V. Fokin;M. G. Finn

  • A Microwave-Assisted Click Chemistry Synthesis of 1,4-Disubstituted 1,2,3-Triazoles via a Copper(I)-Catalyzed Three-Component Reaction

    Prasad Appukkuttan;Wim Dehaen;Valery V Fokin;Erik Van der Eycken

  • Inhibitors of HIV‐1 Protease by Using In Situ Click Chemistry

    Matthew Whiting;John Muldoon;Ying-Chuan Lin;Steven M. Silverman

  • Catalytic azide-alkyne cycloaddition: Reactivity and applications

    Peng Wu;Valery V. Fokin

  • A Potent and Highly Selective Inhibitor of Human α-1,3-Fucosyltransferase via Click Chemistry

    Lac V Lee;Michael L Mitchell;Shih-Jung Huang;Valery V Fokin

  • Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report.

    Valentin O Rodionov;Stanislav I Presolski;David Díaz Díaz;Valery V Fokin

  • Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles.

    Tony Horneff;Stepan Chuprakov;Natalia Chernyak;Vladimir Gevorgyan

  • Click chemistry in materials synthesis. 1. Adhesive polymers from copper‐catalyzed azide‐alkyne cycloaddition

    David D. Díaz;Sreenivas Punna;Philipp Holzer;Andrew K. McPherson

  • Structurally diverse dendritic libraries : A highly efficient functionalization approach using Click chemistry

    Michael Malkoch;Michael Malkoch;Kristin Schleicher;Eric Drockenmuller;Eric Drockenmuller;Craig J. Hawker;Craig J. Hawker

  • Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching.

    Warren G Lewis;Fernando G Magallon;Valery V Fokin;M G Finn

Frequent Co-Authors

K. Barry Sharpless
K. Barry Sharpless Scripps Research Institute
M. G. Finn
M. G. Finn Georgia Institute of Technology
Palmer Taylor
Palmer Taylor University of California, San Diego
Peng Wu
Peng Wu Scripps Research Institute
Fahmi Himo
Fahmi Himo Stockholm University
Craig J. Hawker
Craig J. Hawker University of California, Santa Barbara
Nicos A. Petasis
Nicos A. Petasis University of Southern California
Guochen Jia
Guochen Jia Hong Kong University of Science and Technology
Lars Eckmann
Lars Eckmann University of California, San Diego
Charles N. Serhan
Charles N. Serhan Brigham and Women's Hospital

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