Lars Eckmann mostly deals with Microbiology, Immunology, Proinflammatory cytokine, Inflammation and Innate immune system. Lars Eckmann combines subjects such as Epithelium, Chemotaxis, Antibody and Bacteria with his study of Microbiology. His research is interdisciplinary, bridging the disciplines of Carcinogenesis and Immunology.
His Proinflammatory cytokine research includes themes of Tumor necrosis factor alpha, Interleukin 8, Cytokine, Chemokine and Molecular biology. As a part of the same scientific family, Lars Eckmann mostly works in the field of Cytokine, focusing on Cancer research and, on occasion, Interleukin 6 and STAT3. His research investigates the connection with Innate immune system and areas like Cell biology which intersect with concerns in Secretion.
His primary areas of investigation include Microbiology, Immunology, Cell biology, Epithelium and Inflammation. Lars Eckmann works mostly in the field of Microbiology, limiting it down to topics relating to Intestinal mucosa and, in certain cases, Cancer research. His study in Innate immune system, Immune system, Proinflammatory cytokine, Cytokine and Immunity are all subfields of Immunology.
Lars Eckmann has included themes like Tumor necrosis factor alpha, Molecular biology and Chemokine in his Proinflammatory cytokine study. Lars Eckmann interconnects Interleukin 22 and Cellular differentiation in the investigation of issues within Cell biology. Lars Eckmann has researched Epithelium in several fields, including Cathelicidin and Bacteria.
Lars Eckmann spends much of his time researching Immunology, Microbiology, Cell biology, Internal medicine and Trichomonas vaginalis. His Immunology study frequently draws connections to adjacent fields such as Liver disease. His Microbiology study integrates concerns from other disciplines, such as Nitroimidazole derivatives, Cell type specific, Intestinal mucosa and Bacterial clearance.
His study in Cell biology is interdisciplinary in nature, drawing from both Mast cell, Cellular differentiation, Intestinal epithelium and Microfold cell. His studies deal with areas such as Tumor necrosis factor alpha, Small intestine, Colitis, Lipopolysaccharide and Salmonella enterica as well as Cytokine. His biological study spans a wide range of topics, including Proinflammatory cytokine and Molecular biology.
Lars Eckmann mainly investigates Immunology, Microbiology, Inflammation, Innate immune system and Immune system. His Immunology research incorporates themes from Liver disease, Portal circulation, Host and Secretion. His study on Metronidazole, Entamoeba histolytica and Trichomonas vaginalis is often connected to Antiparasitic agent as part of broader study in Microbiology.
Lars Eckmann merges Inflammation with Steatohepatitis in his research. His research integrates issues of Fibrosis, Oxidative stress, Genetic model and Hepatic stellate cell in his study of Innate immune system. His biological study deals with issues like Antigen, which deal with fields such as Cell culture, Intestinal epithelium, Stem cell and Intestinal mucosa.
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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.
Florian R. Greten;Lars Eckmann;Tim F. Greten;Jin Mo Park.
IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
Sergei Grivennikov;Eliad Karin;Janos Terzic;Janos Terzic;Daniel Mucida.
Cancer Cell (2009)
A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.
Hyun Chae Jung;L. Eckmann;Suk-Kyun Yang;Asit Panja.
Journal of Clinical Investigation (1995)
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.
Sergei I. Grivennikov;Kepeng Wang;Daniel Mucida;C. Andrew Stewart.
Nod2 Mutation in Crohn's Disease Potentiates NF-κB Activity and IL-1ß Processing
Shin Maeda;Li-Chung Hsu;Hongjun Liu;Laurie A. Bankston.
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface.
Shipra Vaishnava;Cassie L. Behrendt;Anisa S. Ismail;Lars Eckmann.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry
L Eckmann;M F Kagnoff;J Fierer.
Infection and Immunity (1993)
Expression and Regulation of the Human β-Defensins hBD-1 and hBD-2 in Intestinal Epithelium
Deborah A. O’Neil;Edith Martin Porter;Dirk Elewaut;G. Mark Anderson.
Journal of Immunology (1999)
EPITHELIAL CELLS AS SENSORS FOR MICROBIAL INFECTION
M F Kagnoff;L Eckmann.
Journal of Clinical Investigation (1997)
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.
Florian R. Greten;Florian R. Greten;Melek C. Arkan;Melek C. Arkan;Julia Bollrath;Li-Chung Hsu.
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