D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 72 Citations 26,839 115 World Ranking 949 National Ranking 518
Medicine D-index 82 Citations 29,586 152 World Ranking 8659 National Ranking 4695

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

Lars Eckmann mostly deals with Microbiology, Immunology, Proinflammatory cytokine, Inflammation and Innate immune system. Lars Eckmann combines subjects such as Epithelium, Chemotaxis, Antibody and Bacteria with his study of Microbiology. His research is interdisciplinary, bridging the disciplines of Carcinogenesis and Immunology.

His Proinflammatory cytokine research includes themes of Tumor necrosis factor alpha, Interleukin 8, Cytokine, Chemokine and Molecular biology. As a part of the same scientific family, Lars Eckmann mostly works in the field of Cytokine, focusing on Cancer research and, on occasion, Interleukin 6 and STAT3. His research investigates the connection with Innate immune system and areas like Cell biology which intersect with concerns in Secretion.

His most cited work include:

  • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. (2034 citations)
  • IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer (1523 citations)
  • A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. (1079 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Microbiology, Immunology, Cell biology, Epithelium and Inflammation. Lars Eckmann works mostly in the field of Microbiology, limiting it down to topics relating to Intestinal mucosa and, in certain cases, Cancer research. His study in Innate immune system, Immune system, Proinflammatory cytokine, Cytokine and Immunity are all subfields of Immunology.

Lars Eckmann has included themes like Tumor necrosis factor alpha, Molecular biology and Chemokine in his Proinflammatory cytokine study. Lars Eckmann interconnects Interleukin 22 and Cellular differentiation in the investigation of issues within Cell biology. Lars Eckmann has researched Epithelium in several fields, including Cathelicidin and Bacteria.

He most often published in these fields:

  • Microbiology (35.62%)
  • Immunology (32.62%)
  • Cell biology (20.60%)

What were the highlights of his more recent work (between 2014-2021)?

  • Immunology (32.62%)
  • Microbiology (35.62%)
  • Cell biology (20.60%)

In recent papers he was focusing on the following fields of study:

Lars Eckmann spends much of his time researching Immunology, Microbiology, Cell biology, Internal medicine and Trichomonas vaginalis. His Immunology study frequently draws connections to adjacent fields such as Liver disease. His Microbiology study integrates concerns from other disciplines, such as Nitroimidazole derivatives, Cell type specific, Intestinal mucosa and Bacterial clearance.

His study in Cell biology is interdisciplinary in nature, drawing from both Mast cell, Cellular differentiation, Intestinal epithelium and Microfold cell. His studies deal with areas such as Tumor necrosis factor alpha, Small intestine, Colitis, Lipopolysaccharide and Salmonella enterica as well as Cytokine. His biological study spans a wide range of topics, including Proinflammatory cytokine and Molecular biology.

Between 2014 and 2021, his most popular works were:

  • Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease (143 citations)
  • Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice (97 citations)
  • Gut-liver axis at the frontier of host-microbial interactions (67 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

Lars Eckmann mainly investigates Immunology, Microbiology, Inflammation, Innate immune system and Immune system. His Immunology research incorporates themes from Liver disease, Portal circulation, Host and Secretion. His study on Metronidazole, Entamoeba histolytica and Trichomonas vaginalis is often connected to Antiparasitic agent as part of broader study in Microbiology.

Lars Eckmann merges Inflammation with Steatohepatitis in his research. His research integrates issues of Fibrosis, Oxidative stress, Genetic model and Hepatic stellate cell in his study of Innate immune system. His biological study deals with issues like Antigen, which deal with fields such as Cell culture, Intestinal epithelium, Stem cell and Intestinal mucosa.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.

Florian R. Greten;Lars Eckmann;Tim F. Greten;Jin Mo Park.
Cell (2004)

2911 Citations

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei Grivennikov;Eliad Karin;Janos Terzic;Janos Terzic;Daniel Mucida.
Cancer Cell (2009)

2011 Citations

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

Hyun Chae Jung;L. Eckmann;Suk-Kyun Yang;Asit Panja.
Journal of Clinical Investigation (1995)

1425 Citations

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth.

Sergei I. Grivennikov;Kepeng Wang;Daniel Mucida;C. Andrew Stewart.
Nature (2012)

980 Citations

Nod2 Mutation in Crohn's Disease Potentiates NF-κB Activity and IL-1ß Processing

Shin Maeda;Li-Chung Hsu;Hongjun Liu;Laurie A. Bankston.
Science (2005)

977 Citations

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface.

Shipra Vaishnava;Cassie L. Behrendt;Anisa S. Ismail;Lars Eckmann.
Proceedings of the National Academy of Sciences of the United States of America (2008)

956 Citations

Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry

L Eckmann;M F Kagnoff;J Fierer.
Infection and Immunity (1993)

806 Citations

Expression and Regulation of the Human β-Defensins hBD-1 and hBD-2 in Intestinal Epithelium

Deborah A. O’Neil;Edith Martin Porter;Dirk Elewaut;G. Mark Anderson.
Journal of Immunology (1999)

804 Citations

EPITHELIAL CELLS AS SENSORS FOR MICROBIAL INFECTION

M F Kagnoff;L Eckmann.
Journal of Clinical Investigation (1997)

754 Citations

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

Florian R. Greten;Florian R. Greten;Melek C. Arkan;Melek C. Arkan;Julia Bollrath;Li-Chung Hsu.
Cell (2007)

723 Citations

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