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D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
24450
World Ranking
2866
National Ranking
1471

Overview

Nissi M. Varki is affiliated with the University of California, San Diego in the United States. Their research spans primarily the fields of biochemistry, genetics, and molecular biology, with additional contributions in medicine. Within these broader categories, their work focuses on several subfields including molecular biology, immunology, cell biology, genetics, and endocrinology.

The scientist's published topics reflect a concentrated interest in areas related to glycobiology and cellular function. Main topics of research include:

  • Glycosylation and glycoproteins research
  • Proteoglycans and glycosaminoglycans research
  • Galectins and cancer biology
  • RNA modifications and cancer
  • Immune cell function and interaction
  • Yersinia bacterium, plague, and ectoparasites research
  • Escherichia coli research studies

The scientist publishes frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Glycobiology, Arteriosclerosis Thrombosis and Vascular Biology, Life Science Alliance, and FASEB BioAdvances. Their recent papers include:

  • "Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss-Brief Report," 2021, Arteriosclerosis Thrombosis and Vascular Biology
  • "DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis," 2020, Life Science Alliance
  • "Human-specific polymorphic pseudogenization of SIGLEC12 protects against advanced cancer progression," 2020, FASEB BioAdvances
  • "Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis," 2021, mBio
  • "Multiple Genomic Events Altering Hominin SIGLEC Biology and Innate Immunity Predated the Common Ancestor of Humans and Archaic Hominins," 2020, Genome Biology and Evolution

The scientist collaborates frequently with a set of coauthors, including Ajit Varki, Naazneen Khan, Andrea Verhagen, Aniruddha Sasmal, and Zahra Khedri. These collaborations suggest an active network within glycobiology and molecular immunology research communities.

Best Publications

  • Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

    Lubor Borsig;Richard Wong;James Feramisco;David R. Nadeau

  • Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

    Taisuke Hosaka;William H. Biggs;David Tieu;Antonia D. Boyer

  • Diversity in cell surface sialic acid presentations: implications for biology and disease

    Nissi M Varki;Ajit Varki

  • Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid

    Pam Tangvoranuntakul;Pascal Gagneux;Sandra Diaz;Muriel Bardor

  • P-selectin deficiency attenuates tumor growth and metastasis.

    Young J. Kim;Lubor Borsig;Nissi M. Varki;Ajit Varki

  • Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody

    Rebecca A. Fleck;L. Vijaya Mohan Rao;Samuel I. Rapaport;Nissi Varki

  • Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis

    Lubor Borsig;Richard Wong;Richard O. Hynes;Nissi M. Varki

  • Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients.

    Gregor Schulz;David A. Cheresh;Nissi M. Varki;Alice Yu

  • A red meat-derived glycan promotes inflammation and cancer progression.

    Annie N. Samraj;Oliver M. T. Pearce;Heinz Läubli;Alyssa N. Crittenden

  • The Ashwell receptor mitigates the lethal coagulopathy of sepsis

    Prabhjit K Grewal;Satoshi Uchiyama;David Ditto;Nissi Varki

  • Cell Differentiation Is a Key Determinant of Cathelicidin LL-37/Human Cationic Antimicrobial Protein 18 Expression by Human Colon Epithelium

    Koji Hase;Lars Eckmann;John D. Leopard;Nissi Varki

  • Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease

    Vered Padler-Karavani;Hai Yu;Hongzhi Cao;Harshal Chokhawala

  • RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

    Olga Turovskaya;Dirk Foell;Pratima Sinha;Thomas Vogl

  • Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.

    Emilie A. Bard-Chapeau;Emilie A. Bard-Chapeau;Shuangwei Li;Jin Ding;Sharon S. Zhang

  • The ST3Gal-I Sialyltransferase Controls CD8+ T Lymphocyte Homeostasis by Modulating O-Glycan Biosynthesis

    John J Priatel;Daniel Chui;Nobuyoshi Hiraoka;Collan J.T Simmons

  • Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas

    Mark Wahrenbrock;Lubor Borsig;Dzung Le;Nissi Varki

  • Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials.

    D. R. Shalinsky;J. Brekken;H. Zou;C. D. Mcdermott

  • Regulated MIP-3α/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity

    Arash Izadpanah;Michael B. Dwinell;Lars Eckmann;Nissi M. Varki

  • Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase

    Miriam Cohen;Xing-Quan Zhang;Hooman P Senaati;Hui-Wen Chen;Hui-Wen Chen

  • Molecular basis of metastasis.

    Ajit Varki;Nissi M Varki;Lubor Borsig

Frequent Co-Authors

Ajit Varki
Ajit Varki University of California, San Diego
Victor Nizet
Victor Nizet University of California, San Diego
Ralph A. Reisfeld
Ralph A. Reisfeld Scripps Research Institute
Xi Chen
Xi Chen University of California, Davis
Lubor Borsig
Lubor Borsig University of Zurich
Lars Eckmann
Lars Eckmann University of California, San Diego
Martin F. Kagnoff
Martin F. Kagnoff University of California, San Diego
Hai Yu
Hai Yu University of California, Davis
Rong Xiang
Rong Xiang Nankai University
Stephen D. Gillies
Stephen D. Gillies MSD (United States)

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