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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
11391
World Ranking
16073
National Ranking
303

Overview

Lubor Borsig is affiliated with the University of Zurich in Switzerland. Their research spans multiple fields with a focus on Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. The scientist has contributed significantly to Oncology, Immunology, Molecular Biology, Cancer Research, and Biotechnology.

The main topics of Lubor Borsig's work include:

  • Immune cells in cancer
  • Peptidase Inhibition and Analysis
  • Virus-based gene therapy research
  • Ubiquitin and proteasome pathways
  • Cancer Cells and Metastasis
  • Glycosylation and Glycoproteins Research
  • Monoclonal and Polyclonal Antibodies Research

Lubor Borsig has published research in a variety of scientific venues. The most frequent venues include:

  • Frontiers in Oncology
  • Neoplasia
  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Host & Microbe

Their recent papers reflect a focus on cancer immunology and tumor microenvironment, with notable publications such as:

  • Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors, 2021, Cell Host & Microbe
  • An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer, 2020, Nature Communications
  • Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels, 2022, Proceedings of the National Academy of Sciences
  • Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells, 2022, Cancers
  • FAP-retargeted Ad5 enables in vivo gene delivery to stromal cells in the tumor microenvironment, 2023, Molecular Therapy

Among frequent collaborators, Lubor Borsig has worked extensively with Merel van Gogh, Marko Roblek, Jesus F. Glaus Garzon, Onur Boyman, and Markus G. Manz.

Best Publications

  • Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

    Lubor Borsig;Richard Wong;James Feramisco;David R. Nadeau

  • P-selectin deficiency attenuates tumor growth and metastasis.

    Young J. Kim;Lubor Borsig;Nissi M. Varki;Ajit Varki

  • Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins.

    Gerd Bendas;Lubor Borsig

  • Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis

    Lubor Borsig;Richard Wong;Richard O. Hynes;Nissi M. Varki

  • Selectins promote tumor metastasis

    Heinz Läubli;Lubor Borsig

  • Altered tumor-cell glycosylation promotes metastasis

    Irina Häuselmann;Lubor Borsig

  • Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas

    Mark Wahrenbrock;Lubor Borsig;Dzung Le;Nissi Varki

  • Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

    Monika Julia Wolf;Alexandra Hoos;Judith Bauer;Steffen Boettcher

  • P-selectin mediates the adhesion of sickle erythrocytes to the endothelium

    Neil M. Matsui;Lubor Borsig;Steven D. Rosen;Mitra Yaghmai

  • Gut microbiota modulate T cell trafficking into human colorectal cancer

    Eleonora Cremonesi;Valeria Governa;Jesus Francisco Glaus Garzon;Valentina Mele

  • Inflammatory chemokines and metastasis—tracing the accessory

    L Borsig;Monika Julia Wolf;Marko Roblek;A Lorentzen

  • Distinct Selectin Ligands on Colon Carcinoma Mucins Can Mediate Pathological Interactions among Platelets, Leukocytes, and Endothelium

    Young J. Kim;Lubor Borsig;Hui-Ling Han;Nissi M. Varki

  • The role of platelet activation in tumor metastasis

    Lubor Borsig

  • Selectin Blocking Activity of a Fucosylated Chondroitin Sulfate Glycosaminoglycan from Sea Cucumber EFFECT ON TUMOR METASTASIS AND NEUTROPHIL RECRUITMENT

    Lubor Borsig;Lianchun Wang;Moises C M Cavalcante;Larissa Cardilo-Reis

  • Altered Cell Adhesion and Glycosylation Promote Cancer Immune Suppression and Metastasis.

    Heinz Läubli;Lubor Borsig

  • L-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrest.

    Heinz Läubli;Jennifer L. Stevenson;Ajit Varki;Nissi M. Varki

  • Milk sialyllactose influences colitis in mice through selective intestinal bacterial colonization

    Andrea Fuhrer;Norbert Sprenger;Ekaterina Kurakevich;Lubor Borsig

  • CCL2-CCR2 Signaling in Disease Pathogenesis

    Tracy O’Connor;Lubor Borsig;Mathias Heikenwalder

  • Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes

    Heinz Läubli;Katharina-Susanne Spanaus;Lubor Borsig

  • Molecular basis of metastasis.

    Ajit Varki;Nissi M Varki;Lubor Borsig

Frequent Co-Authors

Mathias Heikenwalder
Mathias Heikenwalder German Cancer Research Center
Ajit Varki
Ajit Varki University of California, San Diego
Nissi M. Varki
Nissi M. Varki University of California, San Diego
Eric G. Berger
Eric G. Berger University of Zurich
Giulio C. Spagnoli
Giulio C. Spagnoli University Hospital of Basel
Thierry Hennet
Thierry Hennet University of Zurich
Michael O. Hottiger
Michael O. Hottiger University of Zurich
Roland H. Wenger
Roland H. Wenger University of Zurich
Israel Vlodavsky
Israel Vlodavsky Technion – Israel Institute of Technology
Klaus-Peter Janssen
Klaus-Peter Janssen Technical University of Munich

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