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Biology and Biochemistry

D-Index
66
Citations
13605
World Ranking
8801
National Ranking
29

Research.com Recognitions

  • 2002 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1995 - Fellow, The World Academy of Sciences

Overview

Paulo A.S. Mourão is a researcher affiliated with the Federal University of Rio de Janeiro in Brazil. Their work primarily focuses on the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with significant contributions in multiple subfields including Cell Biology, Aquatic Science, Molecular Biology, Internal Medicine, and Surgery.

The research areas of Paulo A.S. Mourão cover a broad spectrum of topics related to the study of complex biological molecules and their medical applications. Key topics include:

  • Proteoglycans and glycosaminoglycans research
  • Seaweed-derived Bioactive Compounds
  • Venous Thromboembolism Diagnosis and Management
  • Marine Sponges and Natural Products
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Blood properties and coagulation
  • Echinoderm biology and ecology

Mourão has published research in a variety of venues, with frequent contributions to journals such as:

  • TH Open
  • Glycobiology
  • Research and Practice in Thrombosis and Haemostasis
  • International Journal of Biological Macromolecules
  • Marine Drugs

Significant recent papers include:

  • Structural characterization of anticoagulant and antithrombotic polysaccharides isolated from Caesalpinia ferrea stem barks, 2021, International Journal of Biological Macromolecules
  • Pharmacological Activities of Sulfated Fucose-Rich Polysaccharides after Oral Administration: Perspectives for the Development of New Carbohydrate-Based Drugs, 2021, Marine Drugs
  • Anticoagulant Activity of Heparins from Different Animal Sources are Driven by a Synergistic Combination of Physical-chemical Factors, 2022, TH Open
  • Inhaled nebulised unfractionated heparin (UFH) for the treatment of hospitalised patients with COVID-19: A randomised controlled pilot study, 2023, Pulmonary Pharmacology & Therapeutics
  • A low-anticoagulant heparin suppresses metastatic dissemination through the inhibition of tumor cell-platelets association, 2024, Biomedicine & Pharmacotherapy

They frequently collaborate with other researchers such as Francisco Felipe Bezerra, Ana Tovar, Eduardo Vilanova, Nina V. Capillé, and Adriana A. Piquet.

Throughout their career, Paulo A.S. Mourão has been recognized by prestigious organizations, including being named a Fellow of the John Simon Guggenheim Memorial Foundation in 2002 and a Fellow of The World Academy of Sciences in 1995.

Best Publications

  • Structure and Anticoagulant Activity of Sulfated Galactans ISOLATION OF A UNIQUE SULFATED GALACTAN FROM THE RED ALGAEBOTRYOCLADIA OCCIDENTALIS AND COMPARISON OF ITS ANTICOAGULANT ACTION WITH THAT OF SULFATED GALACTANS FROM INVERTEBRATES

    Wladimir R.L. Farias;Wladimir R.L. Farias;Ana-Paula Valente;Mariana S. Pereira;Paulo A.S. Mourão

  • Structure and Anticoagulant Activity of Sulfated Fucans COMPARISON BETWEEN THE REGULAR, REPETITIVE, AND LINEAR FUCANS FROM ECHINODERMS WITH THE MORE HETEROGENEOUS AND BRANCHED POLYMERS FROM BROWN ALGAE

    Mariana S. Pereira;Barbara Mulloy;Paulo A. S. Mourão

  • Structure and Anticoagulant Activity of a Fucosylated Chondroitin Sulfate from Echinoderm SULFATED FUCOSE BRANCHES ON THE POLYSACCHARIDE ACCOUNT FOR ITS HIGH ANTICOAGULANT ACTION

    Paulo A.S. Mourão;Mariana S. Pereira;Mauro S.G. Pavão;Barbara Mulloy

  • Structure, biology, evolution, and medical importance of sulfated fucans and galactans.

    Vitor H Pomin;Paulo A S Mourão

  • Structure of a fucose-branched chondroitin sulfate from sea cucumber. Evidence for the presence of 3-O-sulfo-beta-D-glucuronosyl residues.

    R P Vieira;B Mulloy;P A Mourão

  • Occurrence of a unique fucose-branched chondroitin sulfate in the body wall of a sea cucumber.

    R. P. Vieira;P. A. S. Mourao

  • Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives.

    Paulo A S Mourão

  • Searching for Alternatives to Heparin: Sulfated Fucans from Marine Invertebrates

    Paulo A.S. Mourão;Mariana S. Pereira

  • Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans

    Mariana S. Pereira;Fábio R. Melo;Paulo A.S. Mourão

  • The nontoxic mushroom Auricularia auricula contains a polysaccharide with anticoagulant activity mediated by antithrombin.

    Seon Joo Yoon;Seon Joo Yoon;Myeong Ae Yu;Yu Ryang Pyun;Jae Kwan Hwang

  • Sulfated fucans from echinoderms have a regular tetrasaccharide repeating unit defined by specific patterns of sulfation at the 0-2 and 0-4 positions.

    B. Mulloy;A.-C. Ribeiro;A.-P. Alves;R. P. Vieira

  • Highly Sulfated Dermatan Sulfates from Ascidians STRUCTURE VERSUS ANTICOAGULANT ACTIVITY OF THESE GLYCOSAMINOGLYCANS

    Mauro S.G. Pavão;Karin R.M. Aiello;Claudio C. Werneck;Luiz Claudio F. Silva

  • Selectin Blocking Activity of a Fucosylated Chondroitin Sulfate Glycosaminoglycan from Sea Cucumber EFFECT ON TUMOR METASTASIS AND NEUTROPHIL RECRUITMENT

    Lubor Borsig;Lianchun Wang;Moises C M Cavalcante;Larissa Cardilo-Reis

  • Sulfated Polysaccharides from the Egg Jelly Layer Are Species-specific Inducers of Acrosomal Reaction in Sperms of Sea Urchins

    Ana-Paula Alves;Barbara Mulloy;José A. Diniz;Paulo A.S. Mourão

  • Structure and anticoagulant activity of a sulfated galactan from the red alga, Gelidium crinale. Is there a specific structural requirement for the anticoagulant action?

    Maria G. Pereira;Norma M.B. Benevides;Marcia R.S. Melo;Ana Paula Valente

  • Structural and hemostatic activities of a sulfated galactofucan from the brown alga Spatoglossum schroederi. An ideal antithrombotic agent

    Hugo A.O. Rocha;Fábio A. Moraes;Edvaldo S. Trindade;Célia R.C. Franco

  • Antithrombin-mediated anticoagulant activity of sulfated polysaccharides: different mechanisms for heparin and sulfated galactans.

    Fábio R. Melo;Mariana S. Pereira;Débora Foguel;Paulo A.S. Mourão

  • A sulfated α-l-fucan from sea cucumber

    Ana-Cristina Ribeiro;Ricardo P. Vieira;Paulo A.S. Mourão;Barbara Mulloy

  • Glycosaminoglycan fractions from human arteries presenting diverse susceptibilities to atherosclerosis have different binding affinities to plasma LDL.

    L E Cardoso;P A Mourão

  • Structure/function studies of anticoagulant sulphated polysaccharides using NMR.

    B Mulloy;P.A.S Mourão;E Gray

Frequent Co-Authors

Barbara Mulloy
Barbara Mulloy Imperial College London
Radovan Borojevic
Radovan Borojevic Federal University of Rio de Janeiro
Helena B. Nader
Helena B. Nader Federal University of Sao Paulo
Jae-Kwan Hwang
Jae-Kwan Hwang Yonsei University
Victor D. Vacquier
Victor D. Vacquier University of California, San Diego
Douglas M. Tollefsen
Douglas M. Tollefsen Washington University in St. Louis
Lubor Borsig
Lubor Borsig University of Zurich
Anne-Marie Fischer
Anne-Marie Fischer Université Paris Cité
Stevens K. Rehen
Stevens K. Rehen Federal University of Rio de Janeiro
Wilson Savino
Wilson Savino Oswaldo Cruz Foundation

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