World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
10407
World Ranking
17945
National Ranking
7344

Overview

Douglas M. Tollefsen is affiliated with Washington University in St. Louis in the United States. Their body of research spans multiple areas within the broad field of Biochemistry, Genetics, and Molecular Biology, with specific contributions to Molecular Biology and Cell Biology.

Their main topics of work focus on Fibroblast Growth Factor Research and Proteoglycans and glycosaminoglycans research. These areas are central to understanding key biochemical processes involving cellular signaling and extracellular matrix components.

Tollefsen has contributed to scholarly literature, authoring research that includes the paper titled "Role of lysine 173 in heparin binding to heparin cofactor II," published in 2021 through UNC Libraries.

Their collaborations have involved frequent co-authorship with:

  • Herbert C. Whinna
  • Morey A. Blinder
  • Mark Szewczyk
  • Frank Church

Tollefsen's research outputs are recorded primarily within the UNC Libraries publication venue.

Best Publications

  • Development of the human coagulation system in the full-term infant

    Maureen Andrew;Bosco Paes;Ruth Milner;Marilyn Johnston;Marilyn Johnston

  • Development of the human coagulation system in the healthy premature infant

    M Andrew;B Paes;R Milner;M Johnston

  • Activation of heparin cofactor II by dermatan sulfate.

    D M Tollefsen;C A Pestka;W J Monafo

  • Heparin cofactor II. Purification and properties of a heparin-dependent inhibitor of thrombin in human plasma.

    D M Tollefsen;D W Majerus;M K Blank

  • Structure of a dermatan sulfate hexasaccharide that binds to heparin cofactor II with high affinity.

    M M Maimone;D M Tollefsen

  • The Binding of Thrombin to the Surface of Human Platelets

    Douglas M. Tollefsen;John R. Feagler;Philip W. Majerus

  • Structure and Anticoagulant Activity of a Fucosylated Chondroitin Sulfate from Echinoderm SULFATED FUCOSE BRANCHES ON THE POLYSACCHARIDE ACCOUNT FOR ITS HIGH ANTICOAGULANT ACTION

    Paulo A.S. Mourão;Mariana S. Pereira;Mauro S.G. Pavão;Barbara Mulloy

  • Highly Sulfated Dermatan Sulfates from Ascidians STRUCTURE VERSUS ANTICOAGULANT ACTIVITY OF THESE GLYCOSAMINOGLYCANS

    Mauro S.G. Pavão;Karin R.M. Aiello;Claudio C. Werneck;Luiz Claudio F. Silva

  • Detection of a new heparin-dependent inhibitor of thrombin in human plasma.

    Douglas M. Tollefsen;Mary K. Blank

  • The protease specificity of heparin cofactor II. Inhibition of thrombin generated during coagulation.

    K A Parker;D M Tollefsen

  • The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans.

    V. M. D. Van Deerlin;D. M. Tollefsen

  • The contributions of the α2β1 integrin to vascular thrombosis in vivo

    Li He;Loretta K. Pappan;David G. Grenache;Zhengzhi Li

  • Heparin cofactor II inhibits arterial thrombosis after endothelial injury

    Li He;Cristina P. Vicente;Randal J. Westrick;Daniel T. Eitzman

  • A Unique Dermatan Sulfate-like Glycosaminoglycan from Ascidian: ITS STRUCTURE AND THE EFFECT OF ITS UNUSUAL SULFATION PATTERN ON ANTICOAGULANT ACTIVITY

    Mauro S.G. Pavão;Paulo A.S. Mourão;Barbara Mulloy;Douglas M. Tollefsen

  • Insight into the mechanism of action of heparin cofactor II.

    Douglas M Tollefsen

  • N-desulfated/acetylated heparin ameliorates the progression of renal disease in rats with subtotal renal ablation.

    M. L. Purkerson;Douglas Tollefsen;S. Klahr

  • Activation of heparin cofactor II by fibroblasts and vascular smooth muscle cells.

    E A McGuire;D M Tollefsen

  • Heparin cofactor II: cDNA sequence, chromosome localization, restriction fragment length polymorphism, and expression in Escherichia coli.

    Morey A. Blinder;Jayne C. Marasa;Craig H. Reynolds;Larry L. Deaven

  • Heparin Cofactor IIOslo: Mutation of Arg-189 to His Decreases the Affinity for Dermatan Sulfate

    M A Blinder;T R Andersson;U Abildgaard;D M Tollefsen

  • Heparin Cofactor II

    Douglas M. Tollefsen

Frequent Co-Authors

Philip W. Majerus
Philip W. Majerus Washington University in St. Louis
Vivianna M. Van Deerlin
Vivianna M. Van Deerlin University of Pennsylvania
Samuel A. Wickline
Samuel A. Wickline University of South Florida
Paulo A.S. Mourão
Paulo A.S. Mourão Federal University of Rio de Janeiro
Samuel A. Santoro
Samuel A. Santoro Vanderbilt University
Frank C. Church
Frank C. Church University of North Carolina at Chapel Hill
Robert P. Mecham
Robert P. Mecham Washington University in St. Louis
Barbara Mulloy
Barbara Mulloy Imperial College London
Eric A. Jaffe
Eric A. Jaffe Cornell University
J. E. Sadler
J. E. Sadler Washington University in St. Louis

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry in the USA opens doors to a wide range of educational and professional opportunities in healthcare, research, and administration. Many students now prefer flexible online options to further their careers in this evolving field. For those interested in leading healthcare organizations, online mha programs cahme accredited provide advanced skills in health administration with recognized credentials.

Nursing professionals may be drawn to online dnp programs that do not require clinical hours, offering flexibility for working nurses seeking leadership roles. Similarly, individuals aspiring to manage complex health services can pursue a doctorate in healthcare administration online, equipping them with strategic and organizational expertise.

For those passionate about pharmaceuticals, online pharmacy schools deliver advanced knowledge without geographical limitations. Each pathway offers unique career prospects, catering to diverse interests in biology, health sciences, and leadership. Whether you choose research, administration, or clinical practice, online degrees provide flexible options to advance your education and career.

Best Scientists Citing Douglas M. Tollefsen

Recently Published Articles