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Vivianna M. Van Deerlin

Vivianna M. Van Deerlin

D-Index & Metrics

Medicine

D-Index
113
Citations
52033
World Ranking
4913
National Ranking
2661

Overview

Vivianna M. Van Deerlin is affiliated with the University of Pennsylvania in the United States and conducts research primarily in the fields of Medicine and Neuroscience. Their work spans multiple subfields, including Neurology, Physiology, Genetics, Molecular Biology, and Psychiatry and Mental Health. The core focus areas of their research include Parkinson's Disease Mechanisms and Treatments, Alzheimer's Disease Research and Treatments, Neurological Diseases and Metabolism, Amyotrophic Lateral Sclerosis Research, Neuroinflammation and Neurodegeneration Mechanisms, Lysosomal Storage Disorders Research, and Neurogenetic and Muscular Disorders Research.

Van Deerlin has published extensively in a range of scientific venues. Frequent publishing platforms include bioRxiv (Cold Spring Harbor Laboratory), Acta Neuropathologica, Alzheimer's & Dementia, Brain, and Neurology. These venues have hosted numerous contributions from Van Deerlin, reflecting an active engagement with neurological and neuropathological research communities.

Recent papers by Van Deerlin demonstrate a focus on neurodegenerative diseases and genetic factors influencing these conditions. Notable publications include:

  • "TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A," 2022, Nature
  • "Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture," 2021, Nature Genetics
  • "APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease," 2020, Acta Neuropathologica
  • "T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy," 2024, Nature Medicine
  • "The development and convergence of co-pathologies in Alzheimer's disease," 2020, Brain

Van Deerlin collaborates frequently with several researchers, exemplifying a multidisciplinary approach to neuroscience and neuropathology. Frequent coauthors include Edward B. Lee, John Q. Trojanowski, David J. Irwin, Corey T. McMillan, and EunRan Suh, highlighting ongoing research partnerships.

The breadth of Van Deerlin's work reflects in both the volume and variety of research topics and venues. Their contributions address the mechanisms and treatment strategies of neurodegenerative diseases like Alzheimer's and Parkinson's, as well as genetic influences and disease pathology. The scientist's publication record reinforces an emphasis on understanding complex neurological disorders at molecular, genetic, and clinical levels.

Best Publications

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

    Andrew C. Elden;Hyung Jun Kim;Michael P. Hart;Alice S. Chen-Plotkin

  • Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

    Janel O. Johnson;Jessica Mandrioli;Michael Benatar;Yevgeniya Abramzon

  • Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

    Elisa Majounie;Alan E. Renton;Kin Mok;Elise G. P. Dopper;Elise G. P. Dopper

  • Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis

    Johannes Brettschneider;Kelly Del Tredici;Jon B. Toledo;John L. Robinson

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

    Elizabeth T. Cirulli;Brittany N Lasseigne;Slave Petrovski;Peter C Sapp

  • TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

    Vivianna M. Van Deerlin;James B. Leverenz;James B. Leverenz;Lynn M. Bekris;Thomas D. Bird;Thomas D. Bird

  • Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

    John L Robinson;Edward B Lee;Sharon X Xie;Lior Rennert

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

    Wouter van Rheenen;Aleksey Shatunov;Annelot M. Dekker;Russell L. McLaughlin

  • Neuropathologic substrates of Parkinson disease dementia.

    David J. Irwin;Matthew T. White;Jon B. Toledo;Sharon X. Xie

  • Neuropathological and Genetic Correlates of Survival and Dementia Onset in Synucleinopathies: A Retrospective Analysis

    David J Irwin;Murray Grossman;Daniel Weintraub;Daniel Weintraub;Howard I Hurtig

  • Frontotemporal dementia: clinicopathological correlations.

    Mark S. Forman;Jennifer Farmer;Julene K. Johnson;Christopher M. Clark

  • A yeast functional screen predicts new candidate ALS disease genes

    Julien Couthouis;Michael P. Hart;James Shorter;Mariely DeJesus-Hernandez

  • Frontotemporal dementia and its subtypes: a genome-wide association study

    Raffaele Ferrari;Raffaele Ferrari;Dena G Hernandez;Dena G Hernandez;Michael A Nalls;Jonathan D Rohrer

  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

    David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

Frequent Co-Authors

John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
Murray Grossman
Murray Grossman University of Pennsylvania
David J. Irwin
David J. Irwin University of Pennsylvania
Steven E. Arnold
Steven E. Arnold Harvard University
Sharon X. Xie
Sharon X. Xie University of Pennsylvania
Corey T. McMillan
Corey T. McMillan University of Pennsylvania
Edward B. Lee
Edward B. Lee University of Pennsylvania
Bruce L. Miller
Bruce L. Miller University of California, San Francisco

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