World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
88
Citations
27419
World Ranking
13194
National Ranking
6725

Overview

Sharon X. Xie is affiliated with the University of Pennsylvania in the United States and contributes extensively to the field of medicine, with a primary focus on neurology and related disciplines. Their research spans various subfields such as neurology, psychiatry and mental health, physiology, cognitive neuroscience, and statistics and probability.

The scientist's work addresses core topics including dementia and cognitive impairment research, Alzheimer's disease research and treatments, Parkinson's disease mechanisms and treatments, advanced neuroimaging techniques and applications, functional brain connectivity studies, amyotrophic lateral sclerosis research, and neurological disorders and treatments.

Sharon X. Xie has published multiple papers in notable venues. Recent publications include:

  • Distribution patterns of tau pathology in progressive supranuclear palsy, 2020, Acta Neuropathologica
  • The development and convergence of co-pathologies in Alzheimer's disease, 2020, Brain
  • Neurofilament Light Chain as a Biomarker for Cognitive Decline in Parkinson Disease, 2021, Movement Disorders
  • Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated, 2023, Brain
  • Tau deposition patterns are associated with functional connectivity in primary tauopathies, 2022, Nature Communications

The frequent co-authors in Xie's research collaborations include David J. Irwin, Corey T. McMillan, Edward B. Lee, David A. Wolk, and John Q. Trojanowski.

In terms of publication venues, Xie has contributed to journals with significant frequency, such as bioRxiv (Cold Spring Harbor Laboratory), Alzheimer's & Dementia, Acta Neuropathologica, Brain, and Movement Disorders.

Best Publications

  • Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease

    S. Hoops;S. Nazem;A. D. Siderowf;J. E. Duda

  • Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial.

    Gregory K. Brown;Thomas Ten Have;Gregg R. Henriques;Sharon X. Xie

  • Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre

    Jon B. Toledo;Steven E. Arnold;Kevin Raible;Johannes Brettschneider

  • Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

    John L Robinson;Edward B Lee;Sharon X Xie;Lior Rennert

  • Neuropathologic substrates of Parkinson disease dementia.

    David J. Irwin;Matthew T. White;Jon B. Toledo;Sharon X. Xie

  • Neuropathological and Genetic Correlates of Survival and Dementia Onset in Synucleinopathies: A Retrospective Analysis

    David J Irwin;Murray Grossman;Daniel Weintraub;Daniel Weintraub;Howard I Hurtig

  • Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases.

    Hanae Nakashima-Yasuda;Kunihiro Uryu;John Robinson;Sharon X. Xie

  • The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

    Bin Zhang;Jenna Carroll;John Q. Trojanowski;Yuemang Yao

  • Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

    Bin Zhang;Arpita Maiti;Sharon Shively;Fara Lakhani

  • Cerebrospinal Fluid Tau and β-Amyloid: How Well Do These Biomarkers Reflect Autopsy-Confirmed Dementia Diagnoses?

    Christopher M. Clark;Sharon Xie;Jesse Chittams;Douglas Ewbank

  • Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging.

    David R. Roalf;Paul J. Moberg;Sharon X. Xie;David A. Wolk

  • White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities

    Jessica Alber;Suvarna Alladi;Hee Joon Bae;David A. Barton

  • Distribution patterns of tau pathology in progressive supranuclear palsy

    Gabor G. Kovacs;Gabor G. Kovacs;Gabor G. Kovacs;Milica Jecmenica Lukic;Milica Jecmenica Lukic;David J. Irwin;Thomas Arzberger

  • CSF amyloid {beta} 1-42 predicts cognitive decline in Parkinson disease.

    A. Siderowf;S.X. Xie;H. Hurtig;D. Weintraub

  • Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.

    Aaron M. Koenig;Dawn Mechanic-Hamilton;Sharon X. Xie;Martha F. Combs

  • Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis.

    Felix Geser;Nicholas J. Brandmeir;Linda K. Kwong;Maria Martinez-Lage

  • Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale

    Daniel Weintraub;Eugenia Mamikonyan;Kimberly Papay;Judith A. Shea;Judith A. Shea

  • Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy

    Kurt R. Brunden;Bin Zhang;Jenna Carroll;Yuemang Yao

  • Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias

    Mark Yarchoan;Sharon X. Xie;Mitchel A. Kling;Mitchel A. Kling;Jon B. Toledo

  • Cognitive Therapy for the Prevention of Suicide Attempts

    Gregory K. Brown;Gregg R. Henriques;Sharon X. Xie;Judd E. Hollander

Frequent Co-Authors

John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Murray Grossman
Murray Grossman University of Pennsylvania
Steven E. Arnold
Steven E. Arnold Harvard University
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
Daniel Weintraub
Daniel Weintraub University of Pennsylvania
Vivianna M. Van Deerlin
Vivianna M. Van Deerlin University of Pennsylvania
Andrew Siderowf
Andrew Siderowf University of Pennsylvania
David A. Wolk
David A. Wolk University of Pennsylvania
David J. Irwin
David J. Irwin University of Pennsylvania
John E. Duda
John E. Duda University of Pennsylvania

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring healthcare education doesn’t end with traditional medical school. There are several flexible online degree options and pathways that can play a pivotal role in expanding your skills and launching specialized careers in healthcare.

Interested in disease prevention and wellness? An online degree nutrition program can open doors to careers in dietetics, public health, and wellness coaching. Those looking to step into healthcare administration might benefit from pursuing one of the many online mha programs available, many of which are CAHME-accredited. These programs are ideal for future healthcare managers and leaders.

For registered nurses, moving forward professionally doesn’t have to mean putting your career on hold. Innovative rn to bsn programs no clinicals allow RNs to advance their qualifications without the need for extra clinical hours. Additionally, those already holding a master’s in nursing can find the shortest post master's dnp program to efficiently earn their Doctor of Nursing Practice and open doors to advanced roles in clinical practice or education.

These flexible online options provide valuable, diverse career pathways within the evolving healthcare landscape.

Best Scientists Citing Sharon X. Xie

Trending Scientists