World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
143
Citations
79721
World Ranking
1510
National Ranking
878

Overview

Leslie M. Shaw is affiliated with the University of Pennsylvania in the United States and has contributed extensively to research in medicine, with a particular focus on physiology, psychiatry and mental health, neurology, cognitive neuroscience, and molecular biology.

Their research is prominently centered on topics such as Alzheimer's disease research and treatments, dementia and cognitive impairment research, functional brain connectivity studies, Parkinson's disease mechanisms and treatments, advanced neuroimaging techniques and applications, health, environment, cognitive aging, and metabolomics and mass spectrometry studies.

Recent papers authored or co-authored by Leslie M. Shaw include:

  • Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease (2020, Nature Communications)
  • Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative (2020, Molecular Psychiatry)
  • Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease (2020, Nature Communications)
  • Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease (2021, JAMA Neurology)
  • Characterization of pre-analytical sample handling effects on a panel of Alzheimer's disease-related blood-based biomarkers: Results from the Standardization of Alzheimer's Blood Biomarkers (SABB) working group (2021, Alzheimer s & Dementia)

Frequent collaborators of Leslie M. Shaw include:

  • John C. Morris
  • Clifford R. Jack
  • Andrew J. Saykin
  • Michael W. Weiner
  • Arthur W. Toga

Leslie M. Shaw publishes regularly in several venues with notable frequency, which include:

  • Alzheimer s & Dementia
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • JAMA Neurology

Best Publications

  • Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

    Clifford R Jack;David S Knopman;William J Jagust;Leslie M Shaw

  • Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers.

    Clifford R Jack;David S Knopman;William J Jagust;Ronald C Petersen

  • Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects.

    Leslie M. Shaw;Hugo Vanderstichele;Malgorzata Knapik-Czajka;Christopher M. Clark

  • Alzheimer's Disease Neuroimaging Initiative (ADNI): clinical characterization.

    R. C. Petersen;P. S. Aisen;Laurel A Beckett;M. C. Donohue

  • The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.

    Michael W. Weiner;Michael W. Weiner;Dallas P. Veitch;Paul S. Aisen;Laurel A Beckett

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers.

    N. Schuff;N. Schuff;N. Woerner;L. Boreta;T. Kornfield

  • CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

    Oskar Hansson;John Seibyl;Erik Stomrud;Henrik Zetterberg

  • Comparing predictors of conversion and decline in mild cognitive impairment

    S. M. Landau;Danielle J Harvey;C. M. Madison;E. M. Reiman

  • Prediction of MCI to AD conversion, via MRI, CSF biomarkers, and pattern classification.

    Christos Davatzikos;Priyanka Bhatt;Leslie M. Shaw;Kayhan N. Batmanghelich

  • Vascular Endothelial Growth Factor Is an Autocrine Survival Factor for Neuropilin-expressing Breast Carcinoma Cells

    Robin E. Bachelder;Aimee Crago;Jun Chung;Melissa A. Wendt

  • Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer’s disease

    Clifford R. Jack;Heather J. Wiste;Prashanthi Vemuri;Stephen D. Weigand

  • The Alzheimer's Disease Neuroimaging Initiative: Progress report and future plans

    Michael W. Weiner;Michael W. Weiner;Paul S. Aisen;Clifford R. Jack;William J. Jagust

  • Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People

    Geert De Meyer;Fred Shapiro;Hugo Vanderstichele;Eugeen Vanmechelen

  • Relationships between biomarkers in aging and dementia.

    William J. Jagust;S. M. Landau;L. M. Shaw;J. Q. Trojanowski

  • Clinical core of the Alzheimer's disease neuroimaging initiative: Progress and plans

    Paul S. Aisen;Ronald C. Petersen;Michael C. Donohue;Anthony Gamst

  • The role of NFAT transcription factors in integrin-mediated carcinoma invasion.

    Sebastien Jauliac;Cristina López-Rodriguez;Cristina López-Rodriguez;Leslie M. Shaw;Lawrence F. Brown

  • MRI and CSF biomarkers in normal, MCI, and AD subjects: predicting future clinical change.

    P. Vemuri;H. J. Wiste;S. D. Weigand;L. M. Shaw

  • Total and Phosphorylated Tau Protein as Biological Markers of Alzheimer's Disease

    Harald Hampel;Kaj Blennow;Leslie M. Shaw;Yvonne C. Hoessler

  • Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics.

    Irena Nowak;Leslie M. Shaw

Frequent Co-Authors

John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Michael W. Weiner
Michael W. Weiner University of California, San Francisco
Kaj Blennow
Kaj Blennow University of Gothenburg
Ronald C. Petersen
Ronald C. Petersen University of Pennsylvania
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Paul S. Aisen
Paul S. Aisen University of Southern California
Andrew J. Saykin
Andrew J. Saykin Indiana University
William J. Jagust
William J. Jagust University of California, Berkeley
Clifford R. Jack
Clifford R. Jack Mayo Clinic
Arthur W. Toga
Arthur W. Toga University of Southern California

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