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David J. Irwin

D-Index & Metrics

Neuroscience

D-Index
75
Citations
23523
World Ranking
1994
National Ranking
954

David J. Irwin publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where David J. Irwin sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 404 publications — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

David J. Irwin D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where David J. Irwin sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 75 D-Index — 80th percentile

80% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Overview

David J. Irwin is affiliated with the University of Pennsylvania in the United States. Their research spans several domains within medicine, with a particular focus on neurology. The main fields of study covered by David J. Irwin include Medicine, with substantial contributions to the subfields of Neurology, Physiology, Psychiatry and Mental Health, Radiology, Nuclear Medicine and Imaging, and Cognitive Neuroscience.

The research topics addressed by David J. Irwin encompass a wide range of neurological and cognitive disorders as well as advanced neuroimaging techniques. Key topics include:

  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Parkinson's Disease Mechanisms and Treatments
  • Advanced Neuroimaging Techniques and Applications
  • Amyotrophic Lateral Sclerosis Research
  • Functional Brain Connectivity Studies
  • Neurological diseases and metabolism

David J. Irwin has an extensive publication record with frequent contributions to prominent venues such as:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Acta Neuropathologica
  • Brain

Among recent papers authored by or associated with David J. Irwin, the following publications illustrate the scope and focus of the work:

  • "SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network," 2021, Nature Methods
  • "Distribution patterns of tau pathology in progressive supranuclear palsy," 2020, Acta Neuropathologica
  • "Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes," 2020, JAMA Neurology
  • "Neurofilament Light Chain as a Biomarker for Cognitive Decline in Parkinson Disease," 2021, Movement Disorders
  • "Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium," 2020, Alzheimer's & Dementia

David J. Irwin has collaborated extensively with several frequent coauthors, continuing research partnerships with:

  • Murray Grossman
  • Corey T. McMillan
  • David A. Wolk
  • Edward B. Lee
  • John Q. Trojanowski

Best Publications

  • Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria

    Günter U Höglinger;Gesine Respondek;Maria Stamelou;Carolin Kurz

  • Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis

    Johannes Brettschneider;Kelly Del Tredici;Jon B. Toledo;John L. Robinson

  • Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

    David J. Irwin;Virginia M.-Y. Lee;John Q. Trojanowski

  • Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

    John L Robinson;Edward B Lee;Sharon X Xie;Lior Rennert

  • Neuropathologic substrates of Parkinson disease dementia.

    David J. Irwin;Matthew T. White;Jon B. Toledo;Sharon X. Xie

  • Neuropathological and Genetic Correlates of Survival and Dementia Onset in Synucleinopathies: A Retrospective Analysis

    David J Irwin;Murray Grossman;Daniel Weintraub;Daniel Weintraub;Howard I Hurtig

  • APOE ε4 increases risk for dementia in pure synucleinopathies.

    Debby Tsuang;James B. Leverenz;Oscar L. Lopez;Ronald L. Hamilton

  • Distribution patterns of tau pathology in progressive supranuclear palsy

    Gabor G. Kovacs;Gabor G. Kovacs;Gabor G. Kovacs;Milica Jecmenica Lukic;Milica Jecmenica Lukic;David J. Irwin;Thomas Arzberger

  • Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes

    Adam S Fleisher;Michael J Pontecorvo;Michael D Devous;Ming Lu

  • Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau181, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease

    Ju-Hee Kang;Ju-Hee Kang;David J. Irwin;Alice S. Chen-Plotkin;Andrew Siderowf

  • Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)

    Johannes Brettschneider;Johannes Brettschneider;Kelly Del Tredici;David J. Irwin;Murray Grossman

  • Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

    David J. Irwin;Todd J. Cohen;Murray Grossman;Steven E. Arnold

  • Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.

    Katrina M. Moore;Jennifer Nicholas;Murray Grossman;Corey T. McMillan

  • TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

    Johannes Brettschneider;Kimihito Arai;Kelly Del Tredici;Jon B. Toledo

  • Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine

    David J. Irwin;Nigel J. Cairns;Murray Grossman;Corey T. McMillan

  • Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration

    Edward B. Lee;Sílvia Porta;G. Michael Baer;Yan Xu

  • Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders

    Bob Olsson;Bob Olsson;Erik Portelius;Erik Portelius;Nicholas C. Cullen;Nicholas C. Cullen;Åsa Sandelius

  • A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank

    Jon B. Toledo;Vivianna M. Van Deerlin;Edward B. Lee;EunRan Suh

  • Deep clinical and neuropathological phenotyping of Pick disease.

    David J. Irwin;Johannes Brettschneider;Corey T. McMillan;Felicia Cooper

  • Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion

    Johannes Brettschneider;Johannes Brettschneider;Vivianna M. Van Deerlin;John L. Robinson;Linda Kwong

  • C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD

    Elaine Y. Liu;Jenny Russ;Kathryn Wu;Donald Neal

Frequent Co-Authors

Murray Grossman
Murray Grossman University of Pennsylvania
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Corey T. McMillan
Corey T. McMillan University of Pennsylvania
Edward B. Lee
Edward B. Lee University of Pennsylvania
David A. Wolk
David A. Wolk University of Pennsylvania
Vivianna M. Van Deerlin
Vivianna M. Van Deerlin University of Pennsylvania
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
Leslie M. Shaw
Leslie M. Shaw University of Pennsylvania
Bruce L. Miller
Bruce L. Miller University of California, San Francisco
Rosa Rademakers
Rosa Rademakers University of Antwerp

External Links

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Best Scientists Citing David J. Irwin

Kaj Blennow

Kaj Blennow

University of Gothenburg

Publications: 166

James B. Rowe

James B. Rowe

University of Cambridge

Publications: 146

John Q. Trojanowski

John Q. Trojanowski

University of Pennsylvania

Publications: 144

Henrik Zetterberg

Henrik Zetterberg

University of Gothenburg

Publications: 143

Dennis W. Dickson

Dennis W. Dickson

Mayo Clinic

Publications: 113

Glenda M. Halliday

Glenda M. Halliday

University of Sydney

Publications: 104

Albert C. Ludolph

Albert C. Ludolph

University of Ulm

Publications: 96

Virginia M.-Y. Lee

Virginia M.-Y. Lee

University of Pennsylvania

Publications: 93

Günter U. Höglinger

Günter U. Höglinger

Ludwig Maximilian University of Munich

Publications: 90

John R. Hodges

John R. Hodges

University of Sydney

Publications: 83

Keith A. Josephs

Keith A. Josephs

Mayo Clinic

Publications: 83

Bruce L. Miller

Bruce L. Miller

University of California, San Francisco

Publications: 78

Jonathan D. Rohrer

Jonathan D. Rohrer

University College London

Publications: 71

Gil D. Rabinovici

Gil D. Rabinovici

University of California, San Francisco

Publications: 66

Dag Aarsland

Dag Aarsland

King's College London

Publications: 66

Rosa Rademakers

Rosa Rademakers

University of Antwerp

Publications: 65

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