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Neuroscience

D-Index
94
Citations
32775
World Ranking
943
National Ranking
506

Overview

David A. Wolk is affiliated with the University of Pennsylvania in the United States. Their research spans several fields, with a primary focus in Medicine and Neuroscience. Within these fields, their work particularly addresses Psychiatry and Mental Health, Physiology, Radiology, Nuclear Medicine and Imaging, Neurology, and Cognitive Neuroscience.

Their research targets multiple topics related to brain health and neurodegenerative diseases. Key areas of study include:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's Disease Research and Treatments
  • Advanced Neuroimaging Techniques and Applications
  • Functional Brain Connectivity Studies
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological Disease Mechanisms and Treatments
  • Advanced MRI Techniques and Applications

They have published frequently in several scientific venues, with notable publication counts in:

  • Alzheimer's & Dementia (180 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (32 publications)
  • Brain (12 publications)
  • Neurology (12 publications)
  • Acta Neuropathologica (9 publications)

Among their recent papers are:

  • "MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14,468 individuals worldwide" (2020, Brain)
  • "The development and convergence of co-pathologies in Alzheimer's disease" (2020, Brain)
  • "Disentangling Heterogeneity in Alzheimer's Disease and Related Dementias Using Data-Driven Methods" (2020, Biological Psychiatry)
  • "The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans" (2020, Alzheimer's & Dementia)
  • "Neurofilament Light Chain as a Biomarker for Cognitive Decline in Parkinson Disease" (2021, Movement Disorders)

Frequently collaborating co-authors include:

  • Sandhitsu R. Das
  • Paul A. Yushkevich
  • David J. Irwin
  • Corey T. McMillan
  • Laura E.M. Wisse

Best Publications

  • Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

    Willemijn J. Jansen;Rik Ossenkoppele;Dirk L. Knol;Betty M. Tijms

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.

    Rik Ossenkoppele;Willemijn J Jansen;Gil D Rabinovici;Dirk L Knol

  • Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

    John L Robinson;Edward B Lee;Sharon X Xie;Lior Rennert

  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease

    Jacob W Vogel;Alexandra L Young;Neil P Oxtoby;Ruben Smith

  • Automated Volumetry and Regional Thickness Analysis of Hippocampal Subfields and Medial Temporal Cortical Structures in Mild Cognitive Impairment

    Paul A. Yushkevich;John B. Pluta;Hongzhi Wang;Long Xie

  • Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

    Jacob W. Vogel;Yasser Iturria-Medina;Olof T. Strandberg;Ruben Smith

  • Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan.

    Raymond Pomponio;Guray Erus;Mohamad Habes;Jimit Doshi

  • Comparative accuracies of two common screening instruments for classification of Alzheimer's disease, mild cognitive impairment, and healthy aging.

    David R. Roalf;Paul J. Moberg;Sharon X. Xie;David A. Wolk

  • Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

    Unknown

  • Amyloid imaging in mild cognitive impairment subtypes

    David A. Wolk;David A. Wolk;Julie C. Price;Judy A. Saxton;Beth E. Snitz

  • Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.

    Aaron M. Koenig;Dawn Mechanic-Hamilton;Sharon X. Xie;Martha F. Combs

  • Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease

    Oscar L Lopez;James T Becker;Abdus S Wahed;Judith Saxton

  • MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide.

    Vishnu M Bashyam;Guray Erus;Jimit Doshi;Mohamad Habes

  • Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology.

    Taylor W. Schmitz;R. Nathan Spreng;Michael W. Weiner;Paul Aisen

  • Detection of cortical thickness correlates of cognitive performance: Reliability across MRI scan sessions, scanners, and field strengths.

    B.C. Dickerson;E. Fenstermacher;D.H. Salat;D.A. Wolk

  • A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease.

    Andres M. Lozano;Lisa Fosdick;M. Mallar Chakravarty;Jeannie Marie Leoutsakos

  • Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias

    Mark Yarchoan;Sharon X. Xie;Mitchel A. Kling;Mitchel A. Kling;Jon B. Toledo

  • Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease

    Y. Chen;D. A. Wolk;J. S. Reddin;M. Korczykowski

  • Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

    Alzheimer's Disease Neuroimaging Initiative

  • Basal Cerebral Metabolism May Modulate the Cognitive Effects of Aβ in Mild Cognitive Impairment: An Example of Brain Reserve

    Ann D. Cohen;Julie C. Price;Lisa A. Weissfeld;Jeffrey James

  • Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's disease

    David A. Wolk;Bradford C. Dickerson

Frequent Co-Authors

John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Murray Grossman
Murray Grossman University of Pennsylvania
David J. Irwin
David J. Irwin University of Pennsylvania
Corey T. McMillan
Corey T. McMillan University of Pennsylvania
Daniel Weintraub
Daniel Weintraub University of Pennsylvania
Jon B. Toledo
Jon B. Toledo Houston Methodist
Bradford C. Dickerson
Bradford C. Dickerson Harvard Medical School
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
Andrew E. Budson
Andrew E. Budson Boston University
Kaj Blennow
Kaj Blennow University of Gothenburg

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