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Biology and Biochemistry

D-Index
55
Citations
17509
World Ranking
14788
National Ranking
101

Overview

Iiris Hovatta is affiliated with the University of Helsinki in Finland and has contributed extensively to research in the fields of neuroscience, biochemistry, genetics, molecular biology, and medicine. Their work spans various subfields including molecular biology, genetics, neurology, biological psychiatry, and physiology.

Their research topics cover a range of areas such as:

  • Tryptophan and brain disorders
  • Neuroinflammation and neurodegeneration mechanisms
  • Genetic associations and epidemiology
  • Telomeres, telomerase, and senescence
  • Epigenetics and DNA methylation
  • Neuroscience and neuropharmacology research
  • Stress responses and cortisol

Frequent coauthors in their published work include:

  • Kalevi Trontti
  • Jaana Suvisaari
  • Jaakko Kaprio
  • Joonas Naamanka
  • Sandra Meier

They have published in a variety of scientific venues, with notable frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Neuropsychopharmacology
  • Nature
  • Neuroscience Applied
  • Psychoneuroendocrinology

Significant papers authored or coauthored by Iiris Hovatta include:

  • FinnGen provides genetic insights from a well-phenotyped isolated population, 2023, Nature
  • FinnGen: Unique genetic insights from combining isolated population and national health register data, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses, 2023, Nature Medicine
  • Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length, 2020, The American Journal of Human Genetics
  • Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population, 2023, Nature

Best Publications

  • Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

    Cathryn M. Lewis;Douglas F. Levinson;Lesley H. Wise;Lynn E. DeLisi

  • Identification of seven loci affecting mean telomere length and their association with disease

    Veryan Codd;Christopher P Nelson;Eva Albrecht;Massimo Mangino

  • The transcriptional landscape of age in human peripheral blood

    Marjolein J. Peters;Roby Joehanes;Luke C. Pilling;Claudia Schurmann;Claudia Schurmann

  • Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice

    Iiris Hovatta;Richard S. Tennant;Robert Helton;Robert A. Marr

  • Chromosome 1 loci in Finnish schizophrenia families

    Jesper Ekelund;Iiris Hovatta;Alex Parker;Tiina Paunio

  • Oxidative stress in anxiety and comorbid disorders.

    Iiris Hovatta;Iiris Hovatta;Juuso Juhila;Jonas Donner;Jonas Donner

  • A Genomewide Screen for Schizophrenia Genes in an Isolated Finnish Subpopulation, Suggesting Multiple Susceptibility Loci

    Iiris Hovatta;Teppo Varilo;Jaana Suvisaari;Joseph D. Terwilliger

  • Mitochondrial myopathy induces a starvation-like response

    Henna Tyynismaa;Christopher J. Carroll;Nuno Raimundo;Sofia Tuulikki Ahola-Erkkilä

  • Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22

    Jesper Ekelund;Dirk Lichtermann;Iiris Hovatta;Pekka Ellonen

  • Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathways

    Margarita Muiños-Gimeno;Yolanda Espinosa-Parrilla;Yolanda Espinosa-Parrilla;Monica Guidi;Birgit Kagerbauer

  • The semaphorin 3A receptor may directly regulate the activity of small GTPases.

    Beate Rohm;Belquis Rahim;Bedriska Kleiber;Iiris Hovatta

  • A Susceptibility Locus for Migraine with Aura, on Chromosome 4q24

    Maija Wessman;Mikko Kallela;Mari A. Kaunisto;Pia Marttila

  • Adult mouse brain gene expression patterns bear an embryologic imprint

    Matthew A. Zapala;Iiris Hovatta;Julie A. Ellison;Lisa Wodicka

  • Antagonistic Effects of Rnd1 and RhoD GTPases Regulate Receptor Activity in Semaphorin 3A-Induced Cytoskeletal Collapse

    Silvio M. Zanata;Iiris Hovatta;Beate Rohm;Andreas W. Püschel;Andreas W. Püschel

  • Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q

    Tiina Paunio;Jesper Ekelund;Teppo Varilo;Alex Parker

  • Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study

    Sandra Melanie Meier;Kalevi Trontti;Kirstin Lee Purves;Thomas Damms Als;Thomas Damms Als

  • Mutations in CTC1, Encoding the CTS Telomere Maintenance Complex Component 1, Cause Cerebroretinal Microangiopathy with Calcifications and Cysts

    Anne Polvi;Tarja Linnankivi;Tero Kivelä;Riitta Herva

  • Body mass index is negatively associated with telomere length : a collaborative cross-sectional meta-analysis of 87 observational studies

    Marij Gielen;Geja J Hageman;Evangelia E Antoniou;Katarina Nordfjall

  • Telomere length in circulating leukocytes is associated with lung function and disease

    Eva Albrecht;Elina Sillanpaa;Stefan Karrasch;Alexessander Couto Alves

  • Schizophrenia in the genetic isolate of Finland.

    Iiris Hovatta;Joseph D. Terwilliger;Dirk Lichtermann;Taru Mäkikyrö

Frequent Co-Authors

Jouko Lönnqvist
Jouko Lönnqvist Finnish Institute for Health and Welfare (THL)
Jaana Suvisaari
Jaana Suvisaari Finnish Institute for Health and Welfare (THL)
Jaakko Kaprio
Jaakko Kaprio University of Helsinki
Leena Peltonen
Leena Peltonen University of Helsinki
Joseph D. Terwilliger
Joseph D. Terwilliger Columbia University
Tiina Paunio
Tiina Paunio University of Helsinki
Samuli Ripatti
Samuli Ripatti University of Helsinki
Timo Partonen
Timo Partonen Finnish Institute for Health and Welfare (THL)
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Christian Gieger
Christian Gieger Helmholtz Zentrum München

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