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Rik Ossenkoppele

Rik Ossenkoppele

D-Index & Metrics

Neuroscience

D-Index
82
Citations
29609
World Ranking
1495
National Ranking
24

Overview

Rik Ossenkoppele is affiliated with Lund University in Sweden and primarily conducts research in the field of Medicine. Their work focuses significantly on dementia and cognitive impairment, as well as Alzheimer's disease research and treatments.

Their contributions span various subfields, including Psychiatry and Mental Health, Physiology, Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging, and Neurology. These areas support the multidisciplinary nature of their research into neurological diseases and brain function.

Ossenkoppele's research topics encompass:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Medical Imaging Techniques and Applications
  • Neurological Disease Mechanisms and Treatments
  • Parkinson's Disease Mechanisms and Treatments

Frequent collaborators include:

  • Oskar Hansson
  • Ruben Smith
  • Olof Strandberg
  • Wiesje M. van der Flier
  • Sebastian Palmqvist

Their recent papers cover topics related to Alzheimer's disease pathology and neuroimaging biomarkers. Selected publications include:

  • "Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials" (2022, The Lancet Neurology)
  • "Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline" (2022, Nature Medicine)
  • "Four distinct trajectories of tau deposition identified in Alzheimer's disease" (2021, Nature Medicine)
  • "Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias" (2020, The Lancet Neurology)
  • "The probabilistic model of Alzheimer disease: the amyloid hypothesis revised" (2021, Nature Reviews Neuroscience)

Ossenkoppele frequently publishes in venues such as:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Journal of Nuclear Medicine and Molecular Imaging
  • Brain
  • Alzheimer's Research & Therapy

Best Publications

  • Brain charts for the human lifespan

    Unknown

  • Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

    Willemijn J. Jansen;Rik Ossenkoppele;Dirk L. Knol;Betty M. Tijms

  • Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance

    Yaakov Stern;Eider M. Arenaza-Urquijo;David Bartrés-Faz;Sylvie Belleville

  • PET Imaging of Tau Deposition in the Aging Human Brain

    Michael Schöll;Michael Schöll;Samuel N. Lockhart;Daniel R. Schonhaut;James P. O’Neil

  • Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease.

    Rik Ossenkoppele;Rik Ossenkoppele;Rik Ossenkoppele;Daniel R. Schonhaut;Daniel R. Schonhaut;Michael Schöll;Michael Schöll;Samuel N. Lockhart

  • The effect of physical activity on cognitive function in patients with dementia: A meta-analysis of randomized control trials

    C. Groot;A.M. Hooghiemstra;P.G.H.M. Raijmakers;B.N.M. van Berckel

  • Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.

    Rik Ossenkoppele;Willemijn J Jansen;Gil D Rabinovici;Dirk L Knol

  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease

    Jacob W Vogel;Alexandra L Young;Neil P Oxtoby;Ruben Smith

  • The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features.

    Rik Ossenkoppele;Yolande A. L. Pijnenburg;David C. Perry;Brendan I. Cohn-Sheehy

  • Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials

    Unknown

  • Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline

    Unknown

  • Amyloid-β-independent regulators of tau pathology in Alzheimer disease.

    Rik van der Kant;Lawrence S.B. Goldstein;Rik Ossenkoppele;Rik Ossenkoppele

  • Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

    Jacob W. Vogel;Yasser Iturria-Medina;Olof T. Strandberg;Ruben Smith

  • Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias

    Gaël Chételat;Javier Arbizu;Henryk Barthel;Valentina Garibotto

  • The probabilistic model of Alzheimer disease: the amyloid hypothesis revised.

    Giovanni B Frisoni;Giovanni B Frisoni;Daniele Altomare;Daniele Altomare;Dietmar Rudolf Thal;Federica Ribaldi

  • Discriminative accuracy of [18F]flortaucipir positron emission tomography for Alzheimer disease vs other neurodegenerative disorders

    Rik Ossenkoppele;Rik Ossenkoppele;Gil D. Rabinovici;Ruben Smith;Hanna Cho

  • Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

    Unknown

  • Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer's disease.

    Niklas Mattsson-Carlgren;Emelie Andersson;Shorena Janelidze;Rik Ossenkoppele;Rik Ossenkoppele

  • Associations between tau, Aβ, and cortical thickness with cognition in Alzheimer disease.

    Rik Ossenkoppele;Ruben Smith;Tomas Ohlsson;Olof Strandberg

  • Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging.

    Rik Ossenkoppele;Rik Ossenkoppele;Ruben Smith;Niklas Mattsson-Carlgren;Colin Groot

  • Medial temporal lobe connectivity and its associations with cognition in early Alzheimer's disease.

    David Berron;Danielle van Westen;Rik Ossenkoppele;Rik Ossenkoppele;Olof Strandberg

  • Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease

    Rik Ossenkoppele;Brendan I. Cohn-Sheehy;Renaud La Joie;Jacob W. Vogel

  • Impact of molecular imaging on the diagnostic process in a memory clinic

    Rik Ossenkoppele;Niels D. Prins;Yolande A.L. Pijnenburg;Afina W. Lemstra

  • Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease

    Annapaola Prestia;Anna Caroli;Wiesje M. van der Flier;Rik Ossenkoppele

Frequent Co-Authors

Wiesje M. van der Flier
Wiesje M. van der Flier Vrije Universiteit Amsterdam
Frederik Barkhof
Frederik Barkhof University College London
William J. Jagust
William J. Jagust University of California, Berkeley
Ruben Smith
Ruben Smith Lund University
Agneta Nordberg
Agneta Nordberg Karolinska University Hospital
Michael Schöll
Michael Schöll University of Gothenburg
Giovanni B. Frisoni
Giovanni B. Frisoni University of Geneva
Renaud La Joie
Renaud La Joie University of California, San Francisco

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