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Biology and Biochemistry

D-Index
82
Citations
29092
World Ranking
3646
National Ranking
1818

Overview

Terence A. Partridge is affiliated with the Children's National Health System in the United States. Their research primarily focuses on the molecular biology and medical aspects of muscle physiology and disorders. Over their career, they have contributed substantially to the fields of biochemistry, genetics, and molecular biology, with a notable emphasis on muscle physiology intertwined with tissue engineering and regenerative medicine.

The scientist's work spans several core topics including:

  • Muscle Physiology and Disorders
  • Tissue Engineering and Regenerative Medicine
  • Neurogenetic and Muscular Disorders Research
  • Cardiomyopathy and Myosin Studies
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Genetics, Aging, and Longevity in Model Organisms

Key recent publications by Terence A. Partridge include:

  • "TGF-β-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model," 2020, JCI Insight
  • "Skeletal muscle in health and disease," 2020, Disease Models & Mechanisms
  • "A long-read RNA-seq approach to identify novel transcripts of very large genes," 2020, Genome Research
  • "Human muscle stem cells are refractory to aging," 2021, Aging Cell
  • "Interrogation of Dystrophin and Dystroglycan Complex Protein Turnover After Exon Skipping Therapy," 2021, Journal of Neuromuscular Diseases

The frequent co-authors collaborating with them include:

  • James S. Novak
  • Davi A. G. Mázala
  • Eric P. Hoffman
  • Jyoti K. Jaiswal
  • Ravi Hindupur

The primary venues for Terence A. Partridge's publications are:

  • Journal of Neuromuscular Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Muscle Research and Cell Motility
  • JCI Insight
  • Disease Models & Mechanisms

Within their subfields of study, Terence A. Partridge's work is spread across molecular biology, surgery, genetics, cardiology and cardiovascular medicine, and aging. The work reflects a multidisciplinary approach involving genetics and regenerative medical techniques to address muscular and neuromuscular conditions.

Best Publications

  • Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche.

    Charlotte A. Collins;Charlotte A. Collins;Irwin Olsen;Peter S. Zammit;Louise Heslop

  • An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

    Christoph Lepper;Terence A. Partridge;Chen-Ming Fan

  • Muscle satellite cells adopt divergent fates: a mechanism for self-renewal?

    Peter S. Zammit;Jon P. Golding;Yosuke Nagata;Valérie Hudon

  • Direct isolation of satellite cells for skeletal muscle regeneration.

    Didier Montarras;Jennifer Morgan;Charlotte Collins;Frédéric Relaix

  • Expression of Cd34 and Myf5 Defines the Majority of Quiescent Adult Skeletal Muscle Satellite Cells

    Jonathan R. Beauchamp;Louise Heslop;David S.W. Yu;Shahragim Tajbakhsh

  • The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold:

    Peter S. Zammit;Terence A. Partridge;Zipora Yablonka-Reuveni

  • Pax7 and myogenic progression in skeletal muscle satellite cells.

    Peter S. Zammit;Frederic Relaix;Yosuke Nagata;Ana Pérez Ruiz

  • Dynamics of myoblast transplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source.

    Jonathan R. Beauchamp;Jennifer E. Morgan;Charles N. Pagel;Terence A. Partridge

  • Stem and progenitor cells in skeletal muscle development, maintenance, and therapy.

    Bruno Péault;Michael Rudnicki;Yvan Torrente;Giulio Cossu

  • Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

    Julia Alter;Fang Lou;Adam Rabinowitz;HaiFang Yin

  • Culturing satellite cells from living single muscle fiber explants

    J D Rosenblatt;A I Lunt;D J Parry;T A Partridge

  • Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse.

    Qi Long Lu;Christopher J Mann;Fang Lou;George Bou-Gharios

  • Muscle satellite cells.

    Jennifer E. Morgan;Terence A. Partridge

  • Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles

    Qi Long Lu;Adam Rabinowitz;Yun Chao Chen;Toshifumi Yokota

  • Lack of myostatin results in excessive muscle growth but impaired force generation

    Helge Amthor;Raymond Macharia;Roberto Navarrete;Markus Schuelke

  • Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs.

    Toshifumi Yokota;Qi‐long Lu;Terence Partridge;Masanori Kobayashi

  • Dual regulation of the AMP‐activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle

    M. Ponticos;Qi Long Lu;J. E. Morgan;D. G. Hardie

  • Somatic reversion/suppression of the mouse mdx phenotype in vivo.

    Eric P. Hoffman;Jennifer E. Morgan;Simon C. Watkins;Terence A. Partridge

  • A population of myogenic stem cells that survives skeletal muscle aging

    Charlotte A. Collins;Peter S. Zammit;Ana Pérez Ruiz;Jennifer E. Morgan

  • Lack of myostatin results in excessive muscle growth but impaired force generation (vol 104, pg 1835, 2007)

    H Amthor;R Macharia;R Navarrete;M Schuelke

Frequent Co-Authors

Jennifer E. Morgan
Jennifer E. Morgan University College London
Peter S. Zammit
Peter S. Zammit King's College London
Eric P. Hoffman
Eric P. Hoffman Binghamton University
George Bou-Gharios
George Bou-Gharios University of Liverpool
David Abraham
David Abraham University College London
Shin'ichi Takeda
Shin'ichi Takeda National Center of Neurology and Psychiatry
Francesco Muntoni
Francesco Muntoni University College London
Gareth E. Jones
Gareth E. Jones King's College London
Ketan Patel
Ketan Patel University of Reading
Margaret Buckingham
Margaret Buckingham Institut Pasteur

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