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Jacques P. Tremblay

Jacques P. Tremblay

D-Index & Metrics

Molecular Biology

D-Index
62
Citations
10409
World Ranking
1870
National Ranking
55

Overview

Jacques P. Tremblay is affiliated with Université Laval in Canada and contributes extensively to research in biochemistry, genetics, and molecular biology. With a strong focus on molecular biology, their work spans over 130 publications in this field, alongside significant research in medicine.

Their research topics prominently include:

  • CRISPR and Genetic Engineering
  • Muscle Physiology and Disorders
  • Virus-based gene therapy research
  • RNA Interference and Gene Delivery
  • Pluripotent Stem Cells Research
  • RNA and protein synthesis mechanisms
  • Genetic Neurodegenerative Diseases

Among their recent publications are:

  • Current Clinical Applications of In Vivo Gene Therapy with AAVs (2020, Molecular Therapy)
  • CRISPR-Cas9 delivery strategies with engineered extracellular vesicles (2023, Molecular Therapy - Nucleic Acids)
  • CRISPR-Cas9 Gene Therapy for Duchenne Muscular Dystrophy (2022, Neurotherapeutics)
  • Limb-Girdle Muscular Dystrophies Classification and Therapies (2023, Journal of Clinical Medicine)
  • Delivery of RNAs to Specific Organs by Lipid Nanoparticles for Gene Therapy (2022, Pharmaceutics)

The scientist collaborates regularly with various coauthors, including:

  • Joël Rousseau (25 co-publications)
  • Gabriel Lamothe (15 co-publications)
  • Kelly Godbout (11 co-publications)
  • Cédric Happi Mbakam (11 co-publications)
  • Camille Bouchard (10 co-publications)

Jacques P. Tremblay publishes frequently in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory) with 6 publications
  • Molecular Therapy with 4 publications
  • Frontiers in Medicine with 4 publications
  • Molecular Therapy - Nucleic Acids with 3 publications
  • The CRISPR Journal with 3 publications

Best Publications

  • Stem and progenitor cells in skeletal muscle development, maintenance, and therapy.

    Bruno Péault;Michael Rudnicki;Yvan Torrente;Giulio Cossu

  • Current Clinical Applications of In Vivo Gene Therapy with AAVs.

    Jerry R. Mendell;Jerry R. Mendell;Samiah A. Al-Zaidy;Louise R. Rodino-Klapac;Kimberly Goodspeed

  • Intraarterial Injection of Muscle-Derived Cd34+Sca-1+ Stem Cells Restores Dystrophin in mdx Mice

    Yuan Torrente;Jacques P. Tremblay;Federica Pisati;Marzia Belicchi

  • First test of a ''high-density injection'' protocol for myogenic cell transplantation throughout large volumes of muscles in a Duchenne muscular dystrophy patient: eighteen months follow-up

    Daniel Skuk;Marlyne Goulet;Brigitte Roy;Vincent Piette

  • Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.

    Christophe Pichavant;Annemieke Aartsma-Rus;Paula R Clemens;Kay E Davies

  • Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

    David G Ousterout;Pablo Perez-Pinera;Pratiksha I Thakore;Ami M Kabadi

  • Efficacy of myoblast transplantation in nonhuman primates following simple intramuscular cell injections: toward defining strategies applicable to humans.

    Daniel Skuk;Marlyne Goulet;Brigitte Roy;Jacques P. Tremblay

  • Myoblast transplantation: the current status of a potential therapeutic tool for myopathies.

    Daniel Skuk;Jacques P. Tremblay

  • Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies

    J T Vilquin;P F Kennel;M Paturneau-Jouas;P Chapdelaine

  • Successful Myoblast Transplantation in Primates Depends on Appropriate Cell Delivery and Induction of Regeneration in the Host Muscle

    Daniel Skuk;Brigitte Roy;Marlyne Goulet;Jacques P. Tremblay

  • Resetting the problem of cell death following muscle-derived cell transplantation: detection, dynamics and mechanisms.

    Daniel Skuk;Nicolas J. Caron;Marlyne Goulet;Brigitte Roy

  • Autologous transplantation of muscle precursor cells modified with a lentivirus for muscular dystrophy: human cells and primate models.

    Simon P Quenneville;Pierre Chapdelaine;Daniel Skuk;Matin Paradis

  • Tumor necrosis factor-alpha (TNF-alpha) stimulates chemotactic response in mouse myogenic cells.

    Y Torrente;E El Fahime;N J Caron;R Del Bo

  • Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin.

    J T Vilquin;E Wagner;I Kinoshita;R Roy

  • Transfection of large plasmids in primary human myoblasts.

    P Campeau;P Chapdelaine;S Seigneurin-Venin;B Massie

  • Interleukin-4 improves the migration of human myogenic precursor cells in vitro and in vivo.

    J.F. Lafreniere;P. Mills;M. Bouchentouf;J.P. Tremblay

  • Nucleofection of muscle-derived stem cells and myoblasts with ϕC31 integrase: stable expression of a full-length-dystrophin fusion gene by human myoblasts

    Simon P. Quenneville;Pierre Chapdelaine;Joël Rousseau;Jean Beaulieu

  • Meganucleases can restore the reading frame of a mutated dystrophin.

    P Chapdelaine;C Pichavant;J Rousseau;F Pâques

  • Progress in myoblast transplantation: a potential treatment of dystrophies.

    Daniel Skuk;Jacques P. Tremblay

  • A new pro-migratory activity on human myogenic precursor cells for a synthetic peptide within the E domain of the mechano growth factor

    Philippe Mills;Jean-François Lafrenière;Basma Fattouma Benabdallah;El Mostafa El Fahime

Frequent Co-Authors

Johnny Huard
Johnny Huard The University of Texas Health Science Center at Houston
Richard Robitaille
Richard Robitaille University of Montreal
Jerry R. Mendell
Jerry R. Mendell The Ohio State University
Michele P. Calos
Michele P. Calos Stanford University
Xiao Xiao
Xiao Xiao University of North Carolina at Chapel Hill
Nereo Bresolin
Nereo Bresolin University of Milan
Laurent Grégoire
Laurent Grégoire Université Laval
Elie Haddad
Elie Haddad University of Montreal
Bernard Massie
Bernard Massie National Research Council Canada
Charles A. Gersbach
Charles A. Gersbach Duke University

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