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Genetics

D-Index
59
Citations
16134
World Ranking
3218
National Ranking
1399

Overview

Michele P. Calos is affiliated with Stanford University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with particular attention to molecular biology and genetics as subfields.

Their work encompasses several key topics within genetic engineering and molecular biology, including:

  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery
  • Virus-based Gene Therapy Research

The scientist has contributed findings published in the Journal of Molecular Biology, a venue in which they have at least one recorded publication.

A notable recent paper authored includes:

  • "Nucleofection of phiC31 Integrase Protein Mediates Sequence-Specific Genomic Integration in Human Cells," published in 2020 in the Journal of Molecular Biology

Within their collaborative network, Michele P. Calos has frequently worked with Tuhin K. Guha.

Best Publications

  • Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.

    R B DuBridge;P Tang;H C Hsia;P M Leong

  • Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31.

    Amy C Groth;Matthew Fish;Roel Nusse;Michele P Calos

  • On the formation of spontaneous deletions: the importance of short sequence homologies in the generation of large deletions.

    Alessandra M. Albertini;Murielle Hofer;Michèle P. Calos;Jeffrey H. Miller

  • A phage integrase directs efficient site-specific integration in human cells

    Amy C. Groth;Eric C. Olivares;Bhaskar Thyagarajan;Michele P. Calos

  • Phage integrases: biology and applications.

    Amy C. Groth;Michele P. Calos

  • Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase.

    Bhaskar Thyagarajan;Eric C. Olivares;Roger P. Hollis;Daniel S. Ginsburg

  • Mammalian genomes contain active recombinase recognition sites.

    B. Thyagarajan;M.J. Guimarães;A.C. Groth;M.P. Calos

  • High mutation frequency in DNA transfected into mammalian cells

    Michele P. Calos;Jane S. Lebkowski;Michael R. Botchan

  • Site-specific genomic integration produces therapeutic Factor IX levels in mice

    Eric C. Olivares;Roger P. Hollis;Thomas W. Chalberg;Leonard Meuse

  • DNA sequence for a low-level promoter of the lac repressor gene and an ‘up’ promoter mutation

    Michèle P. Calos

  • Stable nonviral genetic correction of inherited human skin disease

    Susana Ortiz-Urda;Bhaskar Thyagarajan;Douglas R. Keene;Qun Lin

  • Isolation of human sequences that replicate autonomously in human cells.

    P J Krysan;S B Haase;M P Calos

  • Integration specificity of phage phiC31 integrase in the human genome.

    Thomas W. Chalberg;Joylette L. Portlock;Eric C. Olivares;Bhaskar Thyagarajan

  • Directed evolution of a recombinase for improved genomic integration at a native human sequence

    Christopher R. Sclimenti;Bhaskar Thyagarajan;Michele P. Calos

  • Phage R4 integrase mediates site-specific integration in human cells.

    Eric C Olivares;Roger P Hollis;Michele P Calos

  • Autonomous DNA replication in human cells is affected by the size and the source of the DNA.

    S S Heinzel;P J Krysan;C T Tran;M P Calos

  • DNA sequence at the integration sites of the insertion element IS1

    Michèle P. Calos;Lorraine Johnsrud;Jeffrey H. Miller

  • The phiC31 integrase system for gene therapy.

    Michele P Calos

  • Transfected DNA is mutated in monkey, mouse, and human cells.

    J S Lebkowski;R B DuBridge;E A Antell;K S Greisen

  • Replication initiates at multiple locations on an autonomously replicating plasmid in human cells.

    P J Krysan;M P Calos

Frequent Co-Authors

Thomas A. Rando
Thomas A. Rando Stanford University
Jeffrey H Miller
Jeffrey H Miller University of California, Los Angeles
Mark A. Kay
Mark A. Kay Stanford University
Jacques P. Tremblay
Jacques P. Tremblay Université Laval
Paul A. Khavari
Paul A. Khavari Stanford University
Douglas R. Keene
Douglas R. Keene Shriners Hospitals for Children - Portland
Joseph C. Wu
Joseph C. Wu Stanford University
Douglas Vollrath
Douglas Vollrath Stanford University
Christopher H. Contag
Christopher H. Contag Michigan State University
Michael R. Botchan
Michael R. Botchan University of California, Berkeley

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