D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 8,917 118 World Ranking 9087 National Ranking 311

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Gene expression

Lori Frappier focuses on Molecular biology, Cell biology, Replication protein A, DNA replication and Binding domain. Her study in Molecular biology is interdisciplinary in nature, drawing from both Mutation, Virus, Origin of replication and Epstein–Barr virus nuclear antigen 1. Her work carried out in the field of Virus brings together such families of science as Plasma protein binding and Antigen.

Her research integrates issues of Plasmid, IL-2 receptor, CD40, Immunology and DNA-binding domain in her study of Cell biology. Lori Frappier has included themes like HMG-box, Protein subunit, Origin recognition complex and DNA in her Replication protein A study. Her Binding domain study integrates concerns from other disciplines, such as Protein domain and Single-stranded binding protein.

Her most cited work include:

  • Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA (463 citations)
  • Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. (265 citations)
  • Human CD8+ T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing. (229 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Molecular biology, Cell biology, DNA replication, Epstein–Barr virus and Virology. Her studies deal with areas such as Plasmid, Origin of replication, Replication protein A, Mitosis and Nuclear protein as well as Molecular biology. Her Cell biology research is multidisciplinary, incorporating perspectives in Gene expression, MCM complex, Chromatin, Cell cycle and Transcription.

Her DNA replication study combines topics from a wide range of disciplines, such as HMG-box and DNA-binding protein. Her Epstein–Barr virus research is multidisciplinary, incorporating perspectives in Gene silencing, Lytic cycle, DNA damage and Cancer research. Her Origin recognition complex research focuses on SeqA protein domain and how it relates to DNA-binding domain and Ter protein.

She most often published in these fields:

  • Molecular biology (38.98%)
  • Cell biology (33.90%)
  • DNA replication (26.27%)

What were the highlights of her more recent work (between 2013-2021)?

  • Cell biology (33.90%)
  • Epstein–Barr virus (22.88%)
  • Lytic cycle (15.25%)

In recent papers she was focusing on the following fields of study:

Lori Frappier focuses on Cell biology, Epstein–Barr virus, Lytic cycle, Virology and Molecular biology. Her Cell biology research includes elements of Gene expression, DNA damage, Viral replication, Ubiquitin ligase and Viral protein. Epstein–Barr virus is a subfield of Virus that she studies.

Her Lytic cycle study combines topics in areas such as Cell cycle, Cell Cycle Protein, DNA and F-box protein. Lori Frappier performs multidisciplinary study on Molecular biology and GTPase-activating protein in her works. Her work in Histone addresses subjects such as Chromatin, which are connected to disciplines such as DNA replication.

Between 2013 and 2021, her most popular works were:

  • Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation (83 citations)
  • Epstein-Barr Virus EBNA1 Protein Regulates Viral Latency through Effects on let-7 MicroRNA and Dicer (48 citations)
  • Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity. (43 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Gene expression

Lori Frappier spends much of her time researching Epstein–Barr virus, Lytic cycle, Molecular biology, Genome and Regulation of gene expression. Virus and Virology are inextricably linked to her Epstein–Barr virus research. The Virus study combines topics in areas such as RNA, APOBEC, Somatic hypermutation and DNA.

Her research integrates issues of Cell cycle, Cell Cycle Protein and Cell biology in her study of Lytic cycle. Borrowing concepts from GTPase-activating protein, Lori Frappier weaves in ideas under Molecular biology. Her work deals with themes such as Virus latency, Cancer research, microRNA, Messenger RNA and Gene silencing, which intersect with Regulation of gene expression.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA

Alexey Bochkarev;Richard A. Pfuetzner;Aled M. Edwards;Lori Frappier.
Nature (1997)

688 Citations

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization.

Vivian Saridakis;Yi Sheng;Feroz Sarkari;Melissa N. Holowaty.
Molecular Cell (2005)

401 Citations

Human CD8+ T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing.

Neil Blake;Steven Lee;Irina Redchenko;Wendy Thomas.
Immunity (1997)

300 Citations

Structural Basis for the Recognition of DNA Repair Proteins UNG2, XPA, and RAD52 by Replication Factor RPA

Georges Mer;Alexey Bochkarev;Alexey Bochkarev;Rajesh Gupta;Elena Bochkareva.
Cell (2000)

287 Citations

Molecular recognition of p53 and MDM2 by USP7/HAUSP

Yi Sheng;Vivian Saridakis;Feroz Sarkari;Shili Duan.
Nature Structural & Molecular Biology (2006)

278 Citations

Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7.

Melissa N. Holowaty;Mahel Zeghouf;Hong Wu;Judy Tellam.
Journal of Biological Chemistry (2003)

271 Citations

Crystal Structure of the DNA-Binding Domain of the Epstein–Barr Virus Origin-Binding Protein, EBNA1, Bound to DNA

Alexey Bochkarev;Jean A Barwell;Richard A Pfuetzner;Elena Bochkareva.
Cell (1996)

256 Citations

The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single‐stranded DNA binding

Alexey Bochkarev;Alexey Bochkarev;Elena Bochkareva;Elena Bochkareva;Lori Frappier;Aled M. Edwards;Aled M. Edwards.
The EMBO Journal (1999)

216 Citations

EBP2, a Human Protein That Interacts with Sequences of the Epstein-Barr Virus Nuclear Antigen 1 Important for Plasmid Maintenance

Kathy Shire;Derek F. J. Ceccarelli;Tina M. Avolio-Hunter;Lori Frappier.
Journal of Virology (1999)

204 Citations

Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA1

Alexey Bochkarev;Jean A. Barwell;Richard A. Pfuetzner;William Furey.
Cell (1995)

197 Citations

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