World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
31868
World Ranking
9955
National Ranking
724

Overview

Marc Zapatka is affiliated with the German Cancer Research Center in Germany. Their research spans multiple disciplines within medicine and molecular biology, focusing on cancer research and its underlying genetic and immunological mechanisms.

The main fields of study in their work are:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these, their subfields of interest include:

  • Molecular Biology
  • Genetics
  • Oncology
  • Cancer Research
  • Immunology

Zapatka's research topics cover a wide array of cancer-related and immunological subjects such as:

  • Cancer Genomics and Diagnostics
  • Chronic Lymphocytic Leukemia Research
  • DNA Repair Mechanisms
  • Glioma Diagnosis and Treatment
  • Advanced Breast Cancer Therapies
  • Immunodeficiency and Autoimmune Disorders
  • PARP inhibition in cancer therapy

Their contributions are published most frequently in several venues, including:

  • Nature Communications
  • Blood
  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Cancer

Some of the notable recent papers involving Marc Zapatka are:

  • "IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression," 2020, Cell
  • "The landscape of viral associations in human cancers," 2020, Nature Genetics
  • "The landscape of chromothripsis across adult cancer types," 2020, Nature Communications
  • "Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity," 2021, Immunity
  • "Conumee 2.0: enhanced copy-number variation analysis from DNA methylation arrays for humans and mice," 2024, Bioinformatics

Zapatka often collaborates with other researchers in their field. Frequent co-authors include:

  • Peter Lichter
  • Murat Iskar
  • Mario Hlevnjak
  • Verena Thewes
  • Martina Seiffert

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • DNA methylation-based classification of central nervous system tumours

    David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt

  • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

    Jeremy Schwartzentruber;Andrey Korshunov;Xiao Yang Liu;David T.W. Jones

  • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

    Dominik Sturm;Hendrik Witt;Hendrik Witt;Volker Hovestadt;Dong Anh Khuong-Quang

  • The landscape of genomic alterations across childhood cancers

    Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter

  • Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib

    Jennifer A. Woyach;Richard R. Furman;Ta Ming Liu;Hatice Gulcin Ozer

  • The whole-genome landscape of medulloblastoma subtypes

    Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Dissecting the genomic complexity underlying medulloblastoma

    David T. W. Jones;Natalie Jäger;Marcel Kool;Thomas Zichner

  • Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

    Tobias Rausch;David T.W. Jones;Marc Zapatka;Adrian M. Stütz

  • Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

    Sebastian Bender;Sebastian Bender;Yujie Tang;Anders M. Lindroth;Volker Hovestadt

  • Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

    David T W Jones;Barbara Hutter;Natalie Jäger;Andrey Korshunov;Andrey Korshunov

  • Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

    Marcel Kool;David T.W. Jones;Natalie Jäger;Paul A. Northcott

  • Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

    Paul A. Northcott;Catherine Lee;Catherine Lee;Thomas Zichner;Adrian M. Stütz

  • IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

    Ahmed Sadik;Luis F Somarribas Patterson;Selcen Öztürk;Soumya R Mohapatra

  • Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

    Pascal D. Johann;Pascal D. Johann;Serap Erkek;Marc Zapatka;Kornelius Kerl

  • Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

    Volker Hovestadt;David T.W. Jones;Simone Picelli;Wei Wang

  • Active medulloblastoma enhancers reveal subgroup-specific cellular origins

    Charles Y. Lin;Charles Y. Lin;Serap Erkek;Yiai Tong;Linlin Yin

  • The landscape of viral associations in human cancers.

    Marc Zapatka;Ivan Borozan;Daniel S Brewer;Daniel S Brewer;Murat Iskar

  • DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

    Christopher C Oakes;Marc Seifert;Yassen Assenov;Lei Gu

Frequent Co-Authors

Peter Lichter
Peter Lichter German Cancer Research Center
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Roland Eils
Roland Eils Charité - University Medicine Berlin
David T. W. Jones
David T. W. Jones German Cancer Research Center
Marcel Kool
Marcel Kool German Cancer Research Center
Paul A. Northcott
Paul A. Northcott St. Jude Children's Research Hospital
Benedikt Brors
Benedikt Brors German Cancer Research Center
Andreas von Deimling
Andreas von Deimling Heidelberg University
Guido Reifenberger
Guido Reifenberger Heinrich Heine University Düsseldorf
Jan O. Korbel
Jan O. Korbel European Molecular Biology Laboratory

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Career opportunities in Biology and Biochemistry are diverse and often intersect with healthcare, research, and allied sciences. Online degrees are increasingly popular for students seeking flexibility and accelerated learning options.

For those interested in healthcare, many professionals pursue the cheapest rn to bsn online programs to build on existing nursing credentials while balancing work and study. Similarly, leadership roles in health settings are accessible through the fastest online mha programs, which help students quickly gain essential management expertise.

Careers focused on specialized patient populations, such as mental health, are in high demand. Aspiring nurses can consider fast track mental health nursing degrees to address rising mental health needs. Meanwhile, those combining biochemistry with nutrition fields can benefit from a fast track nutrition degree online, opening doors to wellness, research, and clinical support careers.

Each of these online pathways offers flexible schedules, affordability, and the ability to advance your career quickly—making them ideal complements to a foundation in Biology or Biochemistry.

Best Scientists Citing Marc Zapatka

Trending Scientists