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Carsten J. Kirschning

Carsten J. Kirschning

D-Index & Metrics

Immunology

D-Index
91
Citations
40237
World Ranking
1023
National Ranking
64

Overview

Carsten J. Kirschning is affiliated with the University of Duisburg-Essen in Germany. Their research contributions span multiple areas within medicine, immunology, and molecular biology, reflecting interdisciplinary expertise and collaboration across these fields.

The scientist's main fields of study include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Key subfields that characterize their work are:

  • Immunology
  • Molecular Biology
  • Epidemiology
  • Genetics
  • Cancer Research

Their research prominently addresses topics such as:

  • Immune Response and Inflammation
  • Immunotherapy and Immune Responses
  • Extracellular vesicles in disease
  • Mesenchymal stem cell research
  • Inflammasome and immune disorders
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction

Frequent co-authors of Carsten J. Kirschning include:

  • Jan Buer
  • Rabea J. Madel
  • Peter A. Horn
  • Astrid M. Westendorf
  • Heba Islam

The scientist's publications have appeared in various journals, with the most common venues being:

  • Frontiers in Immunology
  • Cytotherapy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • The Journal of Experimental Medicine

Notable papers by Carsten J. Kirschning include:

  • "Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life," 2021, The Journal of Experimental Medicine
  • "Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model," 2023, Cytotherapy
  • "Hepatitis B virus particles activate B cells through the TLR2-MyD88-mTOR axis," 2021, Cell Death and Disease
  • "Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially affect symptoms in an advanced murine Graft-versus-Host-Disease model," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway," 2022, Frontiers in Immunology

Best Publications

  • Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

    Florian Heil;Hiroaki Hemmi;Hubertus Hochrein;Franziska Ampenberger

  • Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

    Ralf Schwandner;Roman Dziarski;Holger Wesche;Mike Rothe

  • Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

    Stefan Bauer;Carsten J. Kirschning;Hans Häcker;Vanessa Redecke

  • HSP70 as Endogenous Stimulus of the Toll/Interleukin-1 Receptor Signal Pathway

    Ramunas M. Vabulas;Parviz Ahmad-Nejad;Sanghamitra Ghose;Carsten J. Kirschning

  • Human Toll-like Receptor 2 Confers Responsiveness to Bacterial Lipopolysaccharide

    Carsten J. Kirschning;Holger Wesche;T. Merrill Ayres;Mike Rothe

  • Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells

    Ramunas M. Vabulas;Parviz Ahmad-Nejad;Clarissa da Costa;Thomas Miethke

  • Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.

    Catherine Werts;Catherine Werts;Richard I. Tapping;John C. Mathison;Tsung Hsien Chuang

  • Cutting Edge: Inflammatory Signaling by Borrelia burgdorferi Lipoproteins Is Mediated by Toll-Like Receptor 2

    M Hirschfeld;C J Kirschning;R Schwandner;H Wesche

  • Bacterial Lipopolysaccharide Activates NF-κB through Toll-like Receptor 4 (TLR-4) in Cultured Human Dermal Endothelial Cells DIFFERENTIAL EXPRESSION OF TLR-4 AND TLR-2 IN ENDOTHELIAL CELLS

    Emmanuelle Faure;Ozlem Equils;Peter A. Sieling;Lisa Thomas

  • Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of Nuclear Factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

    Ho Yeong Song;Catherine H. Régnier;Carsten J. Kirschning;David V. Goeddel

  • Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes

    Frank X. Zhang;Carsten J. Kirschning;Roberta Mancinelli;Xiao Ping Xu

  • Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling

    Karen Bieback;Egil Lien;Ingo M. Klagge;Elita Avota

  • Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

    Jaklien C. Leemans;Geurt Stokman;Nike Claessen;Kasper M. Rouschop

  • IRAK-M Is a Novel Member of the Pelle/Interleukin-1 Receptor-associated Kinase (IRAK) Family

    Holger Wesche;Xiong Gao;Xiaoxia Li;Carsten J. Kirschning

  • The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway.

    Ramunas M Vabulas;Sibylla Braedel;Norbert Hilf;Harpreet Singh-Jasuja

  • Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

    Vilma Urbonaviciute;Barbara G. Fürnrohr;Silke Meister;Luis Munoz

  • Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota

    Stephanie C. Ganal;Stephanie L. Sanos;Carsten Kallfass;Karin Oberle

  • Cutting Edge: Toll-Like Receptor (TLR)2- and TLR4-Mediated Pathogen Recognition in Resistance to Airborne Infection with Mycobacterium tuberculosis

    Norbert Reiling;Christoph Hölscher;Alexandra Fehrenbach;Svenja Kröger

  • TLR13 Recognizes Bacterial 23S rRNA Devoid of Erythromycin Resistance–Forming Modification

    Marina Oldenburg;Anne Krüger;Ruth Ferstl;Andreas Kaufmann

  • Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis

    Marco Prinz;Folker Garbe;Hauke Schmidt;Alexander Mildner

  • Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection.

    Michael B. Drennan;Delphine Nicolle;Valerie J.F. Quesniaux;Muazzam Jacobs

Frequent Co-Authors

Hermann Wagner
Hermann Wagner Technical University of Munich
Stefan Bauer
Stefan Bauer Philipp University of Marburg
Jan Buer
Jan Buer University of Duisburg-Essen
Shizuo Akira
Shizuo Akira Osaka University
Hubertus Hochrein
Hubertus Hochrein Technical University of Munich
Uwe Koedel
Uwe Koedel Ludwig-Maximilians-Universität München
Ulf Dittmer
Ulf Dittmer University of Duisburg-Essen
Hans-Walter Pfister
Hans-Walter Pfister Ludwig-Maximilians-Universität München
Marina A. Freudenberg
Marina A. Freudenberg University of Freiburg
Thomas Hartung
Thomas Hartung Johns Hopkins University

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