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Immunology

D-Index
94
Citations
27833
World Ranking
939
National Ranking
36

Medicine

D-Index
96
Citations
29432
World Ranking
9788
National Ranking
381

Overview

Sandrine Florquin is affiliated with the University of Amsterdam in the Netherlands and has an extensive publication record primarily in the field of medicine, with a focused expertise in nephrology and immunology. Their research spans multiple subfields including molecular biology, pulmonary and respiratory medicine, and surgery.

Their recent publications cover a range of topics related to kidney diseases, immunopathology, and transplant pathology. Some notable papers include:

  • Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study (2020, The Lancet Microbe)
  • Deep learning-based classification of kidney transplant pathology: a retrospective, multicentre, proof-of-concept study (2021, The Lancet Digital Health)
  • Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration (2020, Frontiers in Immunology)
  • Immunometabolic rewiring of tubular epithelial cells in kidney disease (2022, Nature Reviews Nephrology)
  • The dysregulation of metabolic pathways and induction of the pentose phosphate pathway in renal ischaemia-reperfusion injury (2020, The Journal of Pathology)

The main topics addressed in their work include:

  • Renal Diseases and Glomerulopathies
  • Renal Transplantation Outcomes and Treatments
  • Renal and Vascular Pathologies
  • Chronic Kidney Disease and Diabetes
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Air Quality and Health Impacts
  • Acute Kidney Injury Research

Throughout their career, Florquin has collaborated frequently with a number of coauthors, including Jesper Kers, Joris J. T. H. Roelofs, Nike Claessen, Alessandra Tammaro, and Loes M. Butter. These collaborators have worked closely with Florquin on multiple research projects, contributing to an interconnected body of research.

Their work has been disseminated through various scientific journals and publication venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Pathology
  • Transplantation
  • Journal of the American Society of Nephrology
  • Frontiers in Immunology

Florquin's research focuses on the pathophysiology of kidney diseases, metabolic and immunologic mechanisms underlying renal injury, and the outcomes of renal transplantation. Recent studies also incorporate computational techniques such as deep learning for pathology classification. Their work reflects an interdisciplinary approach combining molecular biology, immunology, and clinical nephrology.

Best Publications

  • The Oxford classification of IgA nephropathy: Rationale, clinicopathological correlations, and classification

    Daniel C. Cattran;Rosanna Coppo;H. Terence Cook;John Feehally

  • The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility

    Ian S.D. Roberts;H. Terence Cook;Stéphan Troyanov;Charles E. Alpers

  • Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

    Shankar S. Iyer;Wilco P. Pulskens;Jeffrey J. Sadler;Loes M. Butter

  • Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

    Jaklien C. Leemans;Geurt Stokman;Nike Claessen;Kasper M. Rouschop

  • Correction: Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation

    Alessandra Tammaro;Jesper Kers;Diba Emal;Ingrid Stroo

  • Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study.

    Bernadette Schurink;Eva Roos;Teodora Radonic;Ellis Barbe

  • The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice

    David J. van Westerloo;Ilona A. Giebelen;Sandrine Florquin;Marco J. Bruno

  • The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis

    David J. van Westerloo;Ilona A. J. Giebelen;Sandrine Florquin;Joost Daalhuisen

  • IL-10 Is an Important Mediator of the Enhanced Susceptibility to Pneumococcal Pneumonia after Influenza Infection

    Koenraad F. van der Sluijs;Leontine J. R. van Elden;Monique Nijhuis;Rob Schuurman

  • Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia

    Sylvia Knapp;Jaklien C. Leemans;Sandrine Florquin;Judith Branger

  • Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo

    Marieke A.D. van Zoelen;Huan Yang;Sandrine Florquin;Joost C.M. Meijers

  • Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis

    N.P. Juffermans;S. Florquin;L. Camoglio;A. Verbon

  • Toll-Like Receptor 2 Plays a Role in the Early Inflammatory Response to Murine Pneumococcal Pneumonia but Does Not Contribute to Antibacterial Defense

    Sylvia Knapp;Catharina W. Wieland;Cornelis van ’t Veer;Osamu Takeuchi

  • Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1–7) or an angiotensin II receptor antagonist†

    Roelie M. Woesten-van Asperen;Rene Lutter;Patricia A. Specht;Gert N. Moll

  • Deep Learning-Based Histopathologic Assessment of Kidney Tissue

    Meyke Hermsen;Thomas de Bel;Marjolijn den Boer;Eric J. Steenbergen

  • Role of Toll-Like Receptor 4 in Gram-Positive and Gram-Negative Pneumonia in Mice

    Judith Branger;Sylvia Knapp;Sebastiaan Weijer;Jaklien C. Leemans

  • The MEST score provides earlier risk prediction in lgA nephropathy

    Sean J. Barbour;Sean J. Barbour;Gabriela Espino-Hernandez;Heather N. Reich;Rosanna Coppo

  • Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury

    Wilco P. Pulskens;Gwendoline J. Teske;Loes M. Butter;Joris J. Roelofs

  • TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives

    Alessandra Tammaro;Marc Derive;Sebastien Gibot;Jaklien C. Leemans

  • Divergent effect of bacillus Calmette–Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: Implications for primate models in tuberculosis vaccine research

    Jan A. M. Langermans;Peter Andersen;Dick van Soolingen;Richard A. W. Vervenne

  • Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice.

    J C Leemans;N P Juffermans;S Florquin;N van Rooijen

Frequent Co-Authors

Tom van der Poll
Tom van der Poll University of Amsterdam
Alex F. de Vos
Alex F. de Vos University of Amsterdam
Joris J. T. H. Roelofs
Joris J. T. H. Roelofs University of Amsterdam
Cornelis van 't Veer
Cornelis van 't Veer University of Amsterdam
Peter Speelman
Peter Speelman University of Amsterdam
Sylvia Knapp
Sylvia Knapp Medical University of Vienna
Ineke J. M. ten Berge
Ineke J. M. ten Berge University of Amsterdam
Michel Goldman
Michel Goldman Université Libre de Bruxelles
Shizuo Akira
Shizuo Akira Osaka University
René Lutter
René Lutter University of Amsterdam

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