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Immunology

D-Index
63
Citations
10555
World Ranking
3076
National Ranking
34

Overview

Sylvia Knapp is affiliated with the Medical University of Vienna in Austria. Their research predominantly spans the fields of Medicine and Immunology and Microbiology, with significant contributions to subfields such as Immunology, Infectious Diseases, Epidemiology, Surgery, and Neurology.

Their main topics of work include:

  • Immune cells in cancer
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Inflammation biomarkers and pathways
  • Immune Cell Function and Interaction
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Transplantation: Methods and Outcomes

Knapp has frequently published in several key scientific venues, among them:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • eLife
  • Science Immunology
  • The Journal of Heart and Lung Transplantation

Significant recent publications include:

  • Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH, 2022, Journal of Hepatology
  • Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient, 2020, The Lancet Respiratory Medicine
  • TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms, 2020, Gut
  • Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling, 2022, Mucosal Immunology
  • IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcus aureus, 2020, Immunity

Collaborations have been a notable aspect of their research career. Frequent coauthors include:

  • Anastasiya Hladik
  • Philipp Starkl
  • Karin Lakovits
  • Riem Gawish
  • Anna-Dorothea Gorki

Best Publications

  • Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

    Merav Cohen;Amir Giladi;Anna-Dorothea Gorki;Dikla Gelbard Solodkin

  • Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia

    Sylvia Knapp;Jaklien C. Leemans;Sandrine Florquin;Judith Branger

  • Diabetes and infection: is there a link?--A mini-review.

    Sylvia Knapp

  • Toll-Like Receptor 2 Plays a Role in the Early Inflammatory Response to Murine Pneumococcal Pneumonia but Does Not Contribute to Antibacterial Defense

    Sylvia Knapp;Catharina W. Wieland;Cornelis van ’t Veer;Osamu Takeuchi

  • Role of Toll-Like Receptor 4 in Gram-Positive and Gram-Negative Pneumonia in Mice

    Judith Branger;Sylvia Knapp;Sebastiaan Weijer;Jaklien C. Leemans

  • Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man

    Alexander Jais;Elisa Einwallner;Omar Sharif;Omar Sharif;Klaus Gossens

  • CD14 is a coreceptor of Toll-like receptors 7 and 9

    Christoph L. Baumann;Irene M. Aspalter;Omar Sharif;Andreas Pichlmair

  • From expression to signaling: roles of TREM-1 and TREM-2 in innate immunity and bacterial infection.

    Omar Sharif;Sylvia Knapp;Sylvia Knapp

  • Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS) : an international expert consensus initiative for improvement of animal modeling in sepsis

    Marcin F. Osuchowski;Alfred Ayala;Soheyl Bahrami;Michael Bauer

  • First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment

    Simona Saluzzo;Simona Saluzzo;Simona Saluzzo;Anna-Dorothea Gorki;Anna-Dorothea Gorki;Batika M.J. Rana;Rui Martins;Rui Martins

  • Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH.

    Unknown

  • Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia.

    Sylvia Knapp;Catharina W. Wieland;Sandrine Florquin;Ralph Pantophlet

  • Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis

    Marcin F. Osuchowski;Alfred Ayala;Soheyl Bahrami;Michael Bauer

  • Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia.

    Sylvia Knapp;Sébastien Gibot;Alex de Vos;Henri H. Versteeg

  • Early-Life Formation of the Microbial and Immunological Environment of the Human Airways.

    Céline Pattaroni;Martin L. Watzenboeck;Sabrina Schneidegger;Silas Kieser

  • Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes.

    Joanna M. Warszawska;Riem Gawish;Omar Sharif;Stefanie Sigel

  • Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection.

    Nina Gratz;Harald Hartweger;Ulrich Matt;Franz Kratochvill

  • Successful treatment of familial Mediterranean fever with Anakinra and outcome after renal transplantation

    Christian Moser;Gudrun Pohl;Isabella Haslinger;Sylvia Knapp

  • The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection

    Christopher Schliehe;Elizabeth K Flynn;Bojan Vilagos;Udochuku Richson

  • Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

    Rui Martins;Rui Martins;Julia Maier;Julia Maier;Anna-Dorothea Gorki;Anna-Dorothea Gorki;Kilian V M Huber

  • PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas

    Daniela Laimer;Helmut Dolznig;Karoline Kollmann;Paul W. Vesely;Paul W. Vesely

Frequent Co-Authors

Tom van der Poll
Tom van der Poll University of Amsterdam
Sandrine Florquin
Sandrine Florquin University of Amsterdam
Giulio Superti-Furga
Giulio Superti-Furga Medical University of Vienna
Fiona Oakley
Fiona Oakley Newcastle University
Alex F. de Vos
Alex F. de Vos University of Amsterdam
Derek A. Mann
Derek A. Mann Newcastle University
Jacques Colinge
Jacques Colinge University of Montpellier
Wilfried Ellmeier
Wilfried Ellmeier Medical University of Vienna
Christoph J. Binder
Christoph J. Binder Medical University of Vienna
Christoph Bock
Christoph Bock Austrian Academy of Sciences

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