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Biology and Biochemistry

D-Index
48
Citations
13227
World Ranking
18226
National Ranking
168

Overview

Wilfried Ellmeier is affiliated with the Medical University of Vienna in Austria. Their research spans multiple domains within biochemistry, genetics, molecular biology, immunology, microbiology, and medicine. Over the course of their career, the scientist has produced a diverse portfolio of publications, focusing on immune cell functions, epigenetics, and molecular signaling pathways.

Their recent notable papers include:

  • "CD4+ Cytotoxic T cells - Phenotype, Function and Transcriptional Networks Controlling Their Differentiation Pathways" (2022) published in Immunology Letters
  • "24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation" (2021) published in Journal of Hepatology
  • "Histone deacetylases as targets in autoimmune and autoinflammatory diseases" (2020) published in Advances in Immunology
  • "Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation" (2020) published in JCI Insight
  • "PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation" (2020) published in Cell Reports

Ellmeier's research focuses on multiple core topics:

  • Immune Cell Function and Interaction
  • Histone Deacetylase Inhibitors Research
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Protein Degradation and Inhibitors
  • PI3K/AKT/mTOR signaling in cancer
  • Epigenetics and DNA Methylation

The scientist has contributed to research in various subfields including immunology, molecular biology, oncology, genetics, and epidemiology. Their work is often published in journals such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Hepatology, Cell Reports, Frontiers in Immunology, and Nature Communications.

Among frequent collaborators associated with Ellmeier are Nicole Boucheron, Ramona Rîca, Shinya Sakaguchi, Marlis Alteneder, and Michael Trauner. These collaborations reflect sustained partnerships in advancing immunological and molecular biological research.

Best Publications

  • Identification of a major co-receptor for primary isolates of HIV-1

    H Deng;R Liu;W Ellmeier;S Choe

  • PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes.

    Zuoming Sun;Christopher W. Arendt;Wilfried Ellmeier;Wilfried Ellmeier;Edward M. Schaeffer;Edward M. Schaeffer

  • Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

    Daniel Mucida;Mohammad Mushtaq Husain;Sawako Muroi;Femke Van Wijk

  • Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

    Masahiro Shinohara;Takako Koga;Kazuo Okamoto;Shinya Sakaguchi

  • The regulation of CD4 and CD8 coreceptor gene expression during T cell development.

    Wilfried Ellmeier;Shinichiro Sawada;Dan R. Littman

  • The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

    Oliver Hantschel;Uwe Rix;Uwe Schmidt;Tilmann Bürckstümmer

  • Mature mRNA 3' end formation stimulates RNA export from the nucleus.

    R Eckner;W Ellmeier;M L Birnstiel

  • Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

    Wilfried Ellmeier;Steffen Jung;Mary Jean Sunshine;Farah Hatam

  • CD8αα-Mediated Survival and Differentiation of CD8 Memory T Cell Precursors

    Loui T. Madakamutil;Urs Christen;Christopher J. Lena;Yiran Wang-Zhu

  • 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR

    Jung-Hyun Park;Stanley Adoro;Stanley Adoro;Philip J Lucas;Sophia D Sarafova;Sophia D Sarafova

  • Tec regulates platelet activation by GPVI in the absence of Btk.

    Ben T. Atkinson;Wilfried Ellmeier;Wilfried Ellmeier;Steve P. Watson;Steve P. Watson

  • Conditional Deletion of Histone Deacetylase 1 in T Cells Leads to Enhanced Airway Inflammation and Increased Th2 Cytokine Production

    Reinhard Grausenburger;Ivan Bilic;Nicole Boucheron;Gordin Zupkovitz

  • An Enhancer That Directs Lineage-Specific Expression of CD8 in Positively Selected Thymocytes and Mature T Cells

    Wilfried Ellmeier;Mary Jean Sunshine;Kasia Losos;Farah Hatam

  • Multiple Developmental Stage–Specific Enhancers Regulate CD8 Expression in Developing Thymocytes and in Thymus-Independent T Cells

    Wilfried Ellmeier;Mary Jean Sunshine;Kasia Losos;Dan R Littman

  • Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation

    Dimitris Kioussis;Wilfried Ellmeier

  • Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development.

    W. Ellmeier;A. Aguzzi;E. Kleiner;R. Kurzbauer

  • Negative regulation of CD8 expression via CD8 enhancer-mediated recruitment of the zinc finger protein MAZR

    Ivan Bilic;Christina Koesters;Christina Koesters;Bernd Unger;Masayuki Sekimata

  • Progress Toward a Human CD4/CCR5 Transgenic Rat Model for De Novo Infection by Human Immunodeficiency Virus Type 1

    Oliver T. Keppler;Frank J. Welte;Tuan A. Ngo;Peggy S. Chin

  • Histone deacetylase function in CD4+ T cells

    Wilfried Ellmeier;Christian Seiser

  • G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof

    Dan R. Littman;Hongkui Deng;Wilfried Ellmeier;Nathaniel R. Landau

Frequent Co-Authors

Dan R. Littman
Dan R. Littman New York University
Christoph Bock
Christoph Bock Austrian Academy of Sciences
Christian Seiser
Christian Seiser Medical University of Vienna
Ichiro Taniuchi
Ichiro Taniuchi RIKEN Center for Integrative Medical Sciences
Sylvia Knapp
Sylvia Knapp Medical University of Vienna
Patrick Matthias
Patrick Matthias Friedrich Miescher Institute
Michael Trauner
Michael Trauner Medical University of Vienna
Peter Valent
Peter Valent Medical University of Vienna
Günter Steiner
Günter Steiner Medical University of Vienna
Keiryn L. Bennett
Keiryn L. Bennett Medical University of Vienna

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