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Biology and Biochemistry

D-Index
59
Citations
12319
World Ranking
12547
National Ranking
114

Overview

Gottfried Baier is affiliated with Innsbruck Medical University in Austria and has an extensive publication record primarily in the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Their research focus spans several subfields including Immunology, Oncology, Molecular Biology, Public Health, Environmental and Occupational Health, and Epidemiology.

The scientist's work explores key topics related to Immune Cell Function and Interaction, CAR-T cell therapy research, Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, T-cell and B-cell Immunology, Mitochondrial Function and Pathology, and Malaria Research and Control.

Recent publications by Gottfried Baier cover a range of current immunological and oncological issues. Some of these include:

  • A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection, 2024, Nature
  • Cerebral Malaria: Current Clinical and Immunological Aspects, 2022, Frontiers in Immunology
  • Tumor rejection in Cblb −/− mice depends on IL-9 and Th9 cells, 2021, Journal for ImmunoTherapy of Cancer
  • Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy, 2020, Cell Communication and Signaling
  • Loss of the orphan nuclear receptor NR2F6 enhances CD8+ T-cell memory via IFN-γ, 2021, Cell Death and Disease

Frequent collaborators include Victoria Klepsch, Kerstin Siegmund, Sebastian Peer, Niκolaus Thuille, and Natascha Hermann-Kleiter. These coauthors appear in multiple joint publications, indicating ongoing research partnerships.

The scientist's work is regularly published in specialized journals with repeated contributions to Frontiers in Immunology, Journal for ImmunoTherapy of Cancer, Cell Communication and Signaling, Cell Death and Disease, and Cancer Immunology Research.

Best Publications

  • A Novel ε-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing†

    Andreas Weidemann;Simone Eggert;Friedrich B M Reinhard;Markus Vogel

  • FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway.

    Erich Gulbins;Reid Bissonnette;Artin Mahboubi;Seamus Martin

  • The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

    Magdalena Paolino;Axel Choidas;Stephanie Wallner;Blanka Pranjic

  • The MAGUK family protein CARD11 is essential for lymphocyte activation.

    Hiromitsu Hara;Teiji Wada;Teiji Wada;Chris Bakal;Ivona Kozieradzki;Ivona Kozieradzki

  • Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

    Marlies Meisel;Reinhard Hinterleitner;Alain Pacis;Li Chen

  • Protein Kinase C θ Affects Ca2+ Mobilization and NFAT Activation in Primary Mouse T Cells

    Christa Pfeifhofer;Kurt Kofler;Thomas Gruber;Nassim Ghaffari Tabrizi

  • Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

    E Gulbins;KM Coggeshall;G Baier;S Katzav

  • Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.

    G. Baier;D. Telford;L. Giampa;K.M. Coggeshall

  • Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes.

    G Baier-Bitterlich;F Uberall;B Bauer;F Fresser

  • Exacerbated vein graft arteriosclerosis in protein kinase Cδ–null mice

    Michael Leitges;Manuel Mayr;Ursula Braun;Ursula Mayr

  • Syk kinase-coupled C-type lectin receptors engage protein kinase C-δ to elicit Card9 adaptor-mediated innate immunity

    Dominikus Strasser;Konstantin Neumann;Hanna Bergmann;Mohlopheni J. Marakalala

  • NFAT pulls the strings during CD4+ T helper cell effector functions

    Natascha Hermann-Kleiter;Gottfried Baier

  • Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution.

    Mirjana Efremova;Dietmar Rieder;Victoria Klepsch;Pornpimol Charoentong

  • Protein kinase Cθ: a new essential superstar on the T-cell stage

    Amnon Altman;Noah Isakov;Gottfried Baier

  • Protein Kinase C θ and ε Promote T-cell Survival by a Rsk-dependent Phosphorylation and Inactivation of BAD

    Corine Bertolotto;Laurence Maulon;Nathalie Filippa;Gottfried Baier

  • Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function.

    N Meller;Y C Liu;T L Collins;N Bonnefoy-Bérard

  • Translocation of PKCθ in T cells is mediated by a nonconventional, PI3-K– and Vav-dependent pathway, but does not absolutely require phospholipase C

    Martin Villalba;Martin Villalba;Kun Bi;Junru Hu;Yoav Altman

  • Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides.

    E Gulbins;K M Coggeshall;G Baier;D Telford

  • Evidence That Atypical Protein Kinase C-λ and Atypical Protein Kinase C-ζ Participate in Ras-mediated Reorganization of the F-actin Cytoskeleton

    Florian Überall;Karina Hellbert;Sonja Kampfer;Karl Maly

  • The potent protein kinase C selective inhibitor AEB071 (Sotrastaurin)represents a new class of immunosuppressive agents affecting early T cell activation

    Jean-Pierre Evenou;Jürgen Wagner;Gerhard Zenke;Volker Brinkmann

Frequent Co-Authors

Michael Leitges
Michael Leitges University of Oslo
Amnon Altman
Amnon Altman La Jolla Institute For Allergy & Immunology
Gerd Utermann
Gerd Utermann Innsbruck Medical University
Josef M. Penninger
Josef M. Penninger University of British Columbia
Andreas Villunger
Andreas Villunger Innsbruck Medical University
Erich Gulbins
Erich Gulbins University of Duisburg-Essen
Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital
Zlatko Trajanoski
Zlatko Trajanoski Innsbruck Medical University
Tomas Mustelin
Tomas Mustelin University of Washington
Dietmar Fuchs
Dietmar Fuchs Innsbruck Medical University

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