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Biology and Biochemistry

D-Index
88
Citations
21932
World Ranking
2754
National Ranking
1423

Overview

Amnon Altman is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research primarily spans the fields of Immunology and Microbiology as well as Biochemistry, Genetics, and Molecular Biology, with a focus on subfields including Immunology, Molecular Biology, Oncology, Biophysics, and Radiology, Nuclear Medicine and Imaging.

The scientist has contributed notably to topics such as T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Nuclear Structure and Function, RNA Research and Splicing, Signaling Pathways in Disease, Toxin Mechanisms and Immunotoxins, and Peptidase Inhibition and Analysis.

Recent papers authored or co-authored by Amnon Altman include:

  • CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition, 2021, Nature Communications
  • T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1, 2021, eLife
  • CD45 pre-exclusion from the tips of microvilli establishes a phosphatase-free zone for early TCR triggering, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy, 2021, Journal for ImmunoTherapy of Cancer
  • Protein Kinase C-η Deficiency Does Not Impair Antiviral Immunity and CD8+ T Cell Activation, 2020, The Journal of Immunology

Amnon Altman's frequent co-authors include Kok-Fai Kong, Yunmin Jung, Lai Wen, Klaus Ley, and Yujiao He. These collaborations have been reflected in publications across various journals.

The scientist's publications appear regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, eLife, Journal for ImmunoTherapy of Cancer, and The Journal of Immunology.

Best Publications

  • Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor.

    M.Teresa De Magistris;Jeff Alexander;Mark Coggeshall;Amnon Altman

  • Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase.

    T Mustelin;K M Coggeshall;A Altman

  • T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation.

    T Mustelin;KM Coggeshall;N Isakov;A Altman

  • Protein kinase C(theta) in T cell activation.

    Noah Isakov;Amnon Altman

  • FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway.

    Erich Gulbins;Reid Bissonnette;Artin Mahboubi;Seamus Martin

  • NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-θ

    Nolwenn Coudronniere;Martin Villalba;Nathan Englund;Amnon Altman

  • Molecular Events Mediating T Cell Activation

    A Altman;K M Coggeshall;T Mustelin

  • NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta.

    N Coudronniere;M Villalba;N Englund;A Altman

  • Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2.

    Amnon Altman;Argyrios N. Theofilopoulos;Robin Weiner;David H. Katz

  • Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation.

    Bi K;Tanaka Y;Coudronniere N;Sugie K

  • Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

    E Gulbins;KM Coggeshall;G Baier;S Katzav

  • Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells.

    G. Baier;D. Telford;L. Giampa;K.M. Coggeshall

  • Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes.

    G Baier-Bitterlich;F Uberall;B Bauer;F Fresser

  • Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product.

    Marcel Deckert;Sophie Tartare-Deckert;Clément Couture;Tomas Mustelin

  • Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon.

    Robert D. Schreiber;Judith L. Pace;Stephen W. Russell;Amnon Altman

  • Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells

    Martin Villalba;Kun Bi;Fernando Rodriguez;Yoshihiko Tanaka

  • PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcRγ to induce slow leukocyte rolling

    Alexander Zarbock;Clare L. Abram;Matthias Hundt;Amnon Altman

  • A Novel Functional Interaction between Vav and PKCθ Is Required for TCR-Induced T Cell Activation

    Martin Villalba;Nolwenn Coudronniere;Marcel Deckert;Emma Teixeiro

  • Protein kinase C-theta phosphorylation of moesin in the actin-binding sequence.

    Salvatore F. Pietromonaco;Peter C. Simons;Amnon Altman;Laurence Elias

  • Protein kinase C theta (PKCθ) : A key player in T cell life and death

    Keitaro Hayashi;Amnon Altman

Frequent Co-Authors

Gottfried Baier
Gottfried Baier Innsbruck Medical University
Yun-Cai Liu
Yun-Cai Liu La Jolla Institute For Allergy & Immunology
Tomas Mustelin
Tomas Mustelin University of Washington
David H. Katz
David H. Katz National Institutes of Health
Erich Gulbins
Erich Gulbins University of Duisburg-Essen
Michael Croft
Michael Croft La Jolla Institute For Allergy & Immunology
Toshiaki Kawakami
Toshiaki Kawakami University of California, San Diego
Emily M. Mace
Emily M. Mace Columbia University
Robert V. Stahelin
Robert V. Stahelin Purdue University West Lafayette
Frank J. Dixon
Frank J. Dixon Scripps Health

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